Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5T3T

Ebola virus VP30 CTD bound to nucleoprotein

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0008270	molecular_function	zinc ion binding
B	0003723	molecular_function	RNA binding
B	0008270	molecular_function	zinc ion binding
C	0003723	molecular_function	RNA binding
C	0008270	molecular_function	zinc ion binding
D	0003723	molecular_function	RNA binding
D	0008270	molecular_function	zinc ion binding
E	0003723	molecular_function	RNA binding
E	0008270	molecular_function	zinc ion binding
F	0003723	molecular_function	RNA binding
F	0008270	molecular_function	zinc ion binding
G	0003723	molecular_function	RNA binding
G	0008270	molecular_function	zinc ion binding
H	0003723	molecular_function	RNA binding
H	0008270	molecular_function	zinc ion binding
I	0003723	molecular_function	RNA binding
I	0008270	molecular_function	zinc ion binding
J	0003723	molecular_function	RNA binding
J	0008270	molecular_function	zinc ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	binding site for residue SO4 A 301

Chain	Residue
A	PHE181
B	HOH446
A	SER182
A	LYS183
A	HIS215
A	HOH404
A	HOH406
A	HOH419
B	ARG179
B	HOH422

site_id	AC2
Number of Residues	5
Details	binding site for residue SO4 A 302

Chain	Residue
A	LYS183
A	HIS215
A	SER216
A	HOH402
A	HOH447

site_id	AC3
Number of Residues	5
Details	binding site for residue SO4 B 301

Chain	Residue
B	LYS183
B	HIS215
B	SER216
B	HOH404
B	HOH410

site_id	AC4
Number of Residues	10
Details	binding site for residue SO4 B 302

Chain	Residue
A	HOH423
A	HOH448
B	PHE181
B	SER182
B	LYS183
B	HIS215
B	HOH401
B	HOH410
B	HOH413
B	HOH422

site_id	AC5
Number of Residues	9
Details	binding site for residue SO4 C 301

Chain	Residue
C	PHE181
C	SER182
C	LYS183
C	HIS215
C	HOH407
C	HOH414
C	HOH423
C	HOH425
C	HOH426

site_id	AC6
Number of Residues	7
Details	binding site for residue SO4 C 302

Chain	Residue
C	LYS183
C	HIS215
C	SER216
C	HOH420
C	HOH423
C	HOH434
C	HOH450

site_id	AC7
Number of Residues	9
Details	binding site for residue SO4 D 301

Chain	Residue
C	ARG179
D	PHE181
D	SER182
D	LYS183
D	HIS215
D	HOH403
D	HOH421
D	HOH429
D	HOH449

site_id	AC8
Number of Residues	5
Details	binding site for residue SO4 D 302

Chain	Residue
C	HOH447
D	LYS183
D	HIS215
D	SER216
D	HOH413

site_id	AC9
Number of Residues	9
Details	binding site for residue SO4 E 301

Chain	Residue
E	PHE181
E	SER182
E	LYS183
E	HIS215
E	HOH403
E	HOH420
E	HOH446
F	ARG179
F	HOH427

site_id	AD1
Number of Residues	4
Details	binding site for residue SO4 E 302

Chain	Residue
E	LYS183
E	HIS215
E	SER216
E	HOH419

site_id	AD2
Number of Residues	5
Details	binding site for residue SO4 E 303

Chain	Residue
E	ARG213
E	PHE222
E	HOH404
E	HOH421
F	THR114

site_id	AD3
Number of Residues	9
Details	binding site for residue SO4 F 301

Chain	Residue
E	HOH437
E	HOH438
F	PHE181
F	SER182
F	LYS183
F	HIS215
F	HOH406
F	HOH409
F	HOH411

site_id	AD4
Number of Residues	4
Details	binding site for residue SO4 F 302

Chain	Residue
F	LYS183
F	HIS215
F	SER216
F	HOH405

site_id	AD5
Number of Residues	2
Details	binding site for residue SO4 F 303

Chain	Residue
F	ASP231
F	ARG232

site_id	AD6
Number of Residues	4
Details	binding site for residue SO4 F 304

Chain	Residue
E	THR114
F	ARG213
F	PHE222
F	HOH401

site_id	AD7
Number of Residues	8
Details	binding site for residue SO4 G 301

Chain	Residue
G	LYS183
G	HIS215
G	HOH412
G	HOH414
G	HOH420
G	HOH424
G	PHE181
G	SER182

site_id	AD8
Number of Residues	4
Details	binding site for residue SO4 G 302

Chain	Residue
G	LYS183
G	HIS215
G	SER216
G	HOH418

site_id	AD9
Number of Residues	2
Details	binding site for residue SO4 G 303

Chain	Residue
G	ARG196
G	ASN244

site_id	AE1
Number of Residues	8
Details	binding site for residue SO4 H 301

Chain	Residue
G	ARG179
H	PHE181
H	SER182
H	LYS183
H	HIS215
H	HOH426
H	HOH427
H	HOH429

site_id	AE2
Number of Residues	4
Details	binding site for residue SO4 H 302

Chain	Residue
H	LYS183
H	HIS215
H	SER216
H	HOH413

site_id	AE3
Number of Residues	3
Details	binding site for residue SO4 H 303

Chain	Residue
G	THR114
H	ARG213
H	HOH411

site_id	AE4
Number of Residues	9
Details	binding site for residue SO4 I 301

Chain	Residue
I	SER182
I	LYS183
I	HIS215
I	HOH408
I	HOH411
I	HOH423
J	ARG179
J	HOH431
J	HOH462

site_id	AE5
Number of Residues	5
Details	binding site for residue SO4 I 302

Chain	Residue
I	LYS183
I	HIS215
I	SER216
I	HOH409
I	HOH425

site_id	AE6
Number of Residues	3
Details	binding site for residue SO4 I 303

Chain	Residue
H	ASP231
H	ARG232
I	ARG160

site_id	AE7
Number of Residues	10
Details	binding site for residue SO4 J 301

Chain	Residue
I	ARG179
I	HOH437
I	HOH455
J	PHE181
J	SER182
J	LYS183
J	HIS215
J	HOH408
J	HOH409
J	HOH431

site_id	AE8
Number of Residues	6
Details	binding site for residue SO4 J 302

Chain	Residue
J	LYS183
J	HIS215
J	SER216
J	HOH403
J	HOH429
J	HOH438

site_id	AE9
Number of Residues	4
Details	binding site for residue SO4 J 303

Chain	Residue
I	THR114
J	ARG213
J	PHE222
J	HOH414

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	50
Details	Motif: {"description":"VP30-binding motif","evidences":[{"source":"PubMed","id":"29290611","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	350
Details	Region: {"description":"Interaction with the nucleoprotein","evidences":[{"source":"PubMed","id":"28593988","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)