5SZK
Structure of human N-terminally engineered Rab1b in complex with the bMERB domain of Mical-cL
Functional Information from GO Data
Chain | GOid | namespace | contents |
B | 0000045 | biological_process | autophagosome assembly |
B | 0000139 | cellular_component | Golgi membrane |
B | 0003924 | molecular_function | GTPase activity |
B | 0003925 | molecular_function | G protein activity |
B | 0005515 | molecular_function | protein binding |
B | 0005525 | molecular_function | GTP binding |
B | 0005737 | cellular_component | cytoplasm |
B | 0005789 | cellular_component | endoplasmic reticulum membrane |
B | 0005794 | cellular_component | Golgi apparatus |
B | 0005829 | cellular_component | cytosol |
B | 0006886 | biological_process | intracellular protein transport |
B | 0006888 | biological_process | endoplasmic reticulum to Golgi vesicle-mediated transport |
B | 0006914 | biological_process | autophagy |
B | 0007030 | biological_process | Golgi organization |
B | 0012505 | cellular_component | endomembrane system |
B | 0015031 | biological_process | protein transport |
B | 0016020 | cellular_component | membrane |
B | 0016787 | molecular_function | hydrolase activity |
B | 0019068 | biological_process | virion assembly |
B | 0030133 | cellular_component | transport vesicle |
B | 0033116 | cellular_component | endoplasmic reticulum-Golgi intermediate compartment membrane |
B | 0034045 | cellular_component | phagophore assembly site membrane |
B | 0048471 | cellular_component | perinuclear region of cytoplasm |
B | 0070062 | cellular_component | extracellular exosome |
B | 0090557 | biological_process | establishment of endothelial intestinal barrier |
B | 1903020 | biological_process | positive regulation of glycoprotein metabolic process |
B | 2000785 | biological_process | regulation of autophagosome assembly |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | binding site for residue MG B 301 |
Chain | Residue |
B | SER22 |
B | ILE38 |
B | THR40 |
B | GNP302 |
site_id | AC2 |
Number of Residues | 22 |
Details | binding site for residue GNP B 302 |
Chain | Residue |
B | SER22 |
B | CYS23 |
B | TYR33 |
B | THR34 |
B | GLU35 |
B | SER36 |
B | TYR37 |
B | SER39 |
B | THR40 |
B | GLY66 |
B | ASN121 |
B | LYS122 |
B | ASP124 |
B | SER151 |
B | ALA152 |
B | LYS153 |
B | MG301 |
B | SER17 |
B | GLY18 |
B | VAL19 |
B | GLY20 |
B | LYS21 |
Functional Information from PROSITE/UniProt
site_id | PS00675 |
Number of Residues | 14 |
Details | SIGMA54_INTERACT_1 Sigma-54 interaction domain ATP-binding region A signature. LLLiGDSGVGKscL |
Chain | Residue | Details |
B | LEU11-LEU24 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | BINDING: BINDING => ECO:0000269|PubMed:20064470, ECO:0000269|PubMed:20651120, ECO:0000269|PubMed:23236136, ECO:0000269|PubMed:27552051, ECO:0007744|PDB:3JZA, ECO:0007744|PDB:3NKV, ECO:0007744|PDB:4HLQ, ECO:0007744|PDB:4I1O, ECO:0007744|PDB:5SZH, ECO:0007744|PDB:5SZK |
Chain | Residue | Details |
B | GLY15 |
site_id | SWS_FT_FI2 |
Number of Residues | 1 |
Details | BINDING: BINDING => ECO:0000269|PubMed:20651120, ECO:0000269|PubMed:23236136, ECO:0000269|PubMed:27552051, ECO:0007744|PDB:3NKV, ECO:0007744|PDB:4HLQ, ECO:0007744|PDB:5SZH, ECO:0007744|PDB:5SZK |
Chain | Residue | Details |
B | TYR33 |
site_id | SWS_FT_FI3 |
Number of Residues | 1 |
Details | BINDING: BINDING => ECO:0000269|PubMed:20651120, ECO:0000269|PubMed:27552051, ECO:0007744|PDB:3NKV, ECO:0007744|PDB:5SZH, ECO:0007744|PDB:5SZK |
Chain | Residue | Details |
B | ASP63 |
site_id | SWS_FT_FI4 |
Number of Residues | 2 |
Details | BINDING: BINDING => ECO:0000269|PubMed:20651120, ECO:0000269|PubMed:23236136, ECO:0000269|PubMed:27552051, ECO:0007744|PDB:3NKV, ECO:0007744|PDB:4HLQ, ECO:0007744|PDB:4I1O, ECO:0007744|PDB:5SZH, ECO:0007744|PDB:5SZK |
Chain | Residue | Details |
B | ASN121 | |
B | SER151 |
site_id | SWS_FT_FI5 |
Number of Residues | 1 |
Details | MOD_RES: N-acetylmethionine => ECO:0000269|Ref.5 |
Chain | Residue | Details |
B | MET1 |
site_id | SWS_FT_FI6 |
Number of Residues | 1 |
Details | MOD_RES: (Microbial infection) O-(2-cholinephosphoryl)serine => ECO:0000269|PubMed:21822290, ECO:0000269|PubMed:22158903, ECO:0000269|PubMed:22307087 |
Chain | Residue | Details |
B | SER76 |
site_id | SWS_FT_FI7 |
Number of Residues | 1 |
Details | MOD_RES: (Microbial infection) O-AMP-tyrosine => ECO:0000269|PubMed:20651120 |
Chain | Residue | Details |
B | TYR77 |
site_id | SWS_FT_FI8 |
Number of Residues | 1 |
Details | MOD_RES: Cysteine methyl ester => ECO:0000255 |
Chain | Residue | Details |
B | CYS201 |
site_id | SWS_FT_FI9 |
Number of Residues | 2 |
Details | LIPID: S-geranylgeranyl cysteine => ECO:0000269|PubMed:8836150 |
Chain | Residue | Details |
B | CYS200 | |
B | CYS201 |