5SZH
Structure of human Rab1b in complex with the bMERB domain of Mical-cL
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0000045 | biological_process | autophagosome assembly |
| B | 0000139 | cellular_component | Golgi membrane |
| B | 0003924 | molecular_function | GTPase activity |
| B | 0003925 | molecular_function | G protein activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005525 | molecular_function | GTP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005789 | cellular_component | endoplasmic reticulum membrane |
| B | 0005794 | cellular_component | Golgi apparatus |
| B | 0005829 | cellular_component | cytosol |
| B | 0006886 | biological_process | intracellular protein transport |
| B | 0006888 | biological_process | endoplasmic reticulum to Golgi vesicle-mediated transport |
| B | 0006914 | biological_process | autophagy |
| B | 0007030 | biological_process | Golgi organization |
| B | 0012505 | cellular_component | endomembrane system |
| B | 0015031 | biological_process | protein transport |
| B | 0016020 | cellular_component | membrane |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0019068 | biological_process | virion assembly |
| B | 0030133 | cellular_component | transport vesicle |
| B | 0033116 | cellular_component | endoplasmic reticulum-Golgi intermediate compartment membrane |
| B | 0034045 | cellular_component | phagophore assembly site membrane |
| B | 0048471 | cellular_component | perinuclear region of cytoplasm |
| B | 0070062 | cellular_component | extracellular exosome |
| B | 0090557 | biological_process | establishment of endothelial intestinal barrier |
| B | 1903020 | biological_process | positive regulation of glycoprotein metabolic process |
| B | 2000785 | biological_process | regulation of autophagosome assembly |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 25 |
| Details | binding site for residue GNP B 301 |
| Chain | Residue |
| B | SER17 |
| B | GLU35 |
| B | TYR37 |
| B | SER39 |
| B | THR40 |
| B | GLY66 |
| B | ASN121 |
| B | LYS122 |
| B | ASP124 |
| B | LEU125 |
| B | SER151 |
| B | GLY18 |
| B | ALA152 |
| B | LYS153 |
| B | MG302 |
| B | HOH404 |
| B | HOH408 |
| B | HOH410 |
| B | VAL19 |
| B | GLY20 |
| B | LYS21 |
| B | SER22 |
| B | CYS23 |
| B | TYR33 |
| B | THR34 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 302 |
| Chain | Residue |
| B | SER22 |
| B | THR40 |
| B | GNP301 |
| B | HOH404 |
| B | HOH410 |
Functional Information from PROSITE/UniProt
| site_id | PS00675 |
| Number of Residues | 14 |
| Details | SIGMA54_INTERACT_1 Sigma-54 interaction domain ATP-binding region A signature. LLLiGDSGVGKscL |
| Chain | Residue | Details |
| B | LEU11-LEU24 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:20064470, ECO:0000269|PubMed:20651120, ECO:0000269|PubMed:23236136, ECO:0000269|PubMed:27552051, ECO:0007744|PDB:3JZA, ECO:0007744|PDB:3NKV, ECO:0007744|PDB:4HLQ, ECO:0007744|PDB:4I1O, ECO:0007744|PDB:5SZH, ECO:0007744|PDB:5SZK |
| Chain | Residue | Details |
| B | GLY15 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:20651120, ECO:0000269|PubMed:23236136, ECO:0000269|PubMed:27552051, ECO:0007744|PDB:3NKV, ECO:0007744|PDB:4HLQ, ECO:0007744|PDB:5SZH, ECO:0007744|PDB:5SZK |
| Chain | Residue | Details |
| B | TYR33 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:20651120, ECO:0000269|PubMed:27552051, ECO:0007744|PDB:3NKV, ECO:0007744|PDB:5SZH, ECO:0007744|PDB:5SZK |
| Chain | Residue | Details |
| B | ASP63 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:20651120, ECO:0000269|PubMed:23236136, ECO:0000269|PubMed:27552051, ECO:0007744|PDB:3NKV, ECO:0007744|PDB:4HLQ, ECO:0007744|PDB:4I1O, ECO:0007744|PDB:5SZH, ECO:0007744|PDB:5SZK |
| Chain | Residue | Details |
| B | ASN121 | |
| B | SER151 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | MOD_RES: N-acetylmethionine => ECO:0000269|Ref.5 |
| Chain | Residue | Details |
| B | MET1 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | MOD_RES: (Microbial infection) O-(2-cholinephosphoryl)serine => ECO:0000269|PubMed:21822290, ECO:0000269|PubMed:22158903, ECO:0000269|PubMed:22307087 |
| Chain | Residue | Details |
| B | SER76 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | MOD_RES: (Microbial infection) O-AMP-tyrosine => ECO:0000269|PubMed:20651120 |
| Chain | Residue | Details |
| B | TYR77 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | MOD_RES: Cysteine methyl ester => ECO:0000255 |
| Chain | Residue | Details |
| B | CYS201 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 2 |
| Details | LIPID: S-geranylgeranyl cysteine => ECO:0000269|PubMed:8836150 |
| Chain | Residue | Details |
| B | CYS200 | |
| B | CYS201 |
