Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue YW7 A 301 |
| Chain | Residue |
| A | TRP81 |
| A | ILE146 |
| A | MET149 |
| A | HOH410 |
| A | HOH423 |
| A | PRO82 |
| A | PHE83 |
| A | GLN85 |
| A | PRO86 |
| A | ASP88 |
| A | LYS91 |
| A | LEU92 |
| A | ASN140 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 302 |
| Chain | Residue |
| A | MET43 |
| A | ASN44 |
| A | VAL90 |
| A | ILE161 |
| A | ASN162 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | binding site for residue YW7 B 301 |
| Chain | Residue |
| B | TRP81 |
| B | PRO82 |
| B | PHE83 |
| B | GLN85 |
| B | PRO86 |
| B | ASP88 |
| B | LYS91 |
| B | LEU92 |
| B | ASN140 |
| B | ILE146 |
| B | MET149 |
| B | HOH406 |
| B | HOH414 |
| site_id | AC4 |
| Number of Residues | 17 |
| Details | binding site for residue YW7 D 301 |
| Chain | Residue |
| B | GLN78 |
| B | HOH409 |
| D | TRP81 |
| D | PRO82 |
| D | PHE83 |
| D | GLN85 |
| D | PRO86 |
| D | ASP88 |
| D | LYS91 |
| D | LEU92 |
| D | ASN140 |
| D | ILE146 |
| D | MET149 |
| D | HOH401 |
| D | HOH417 |
| D | HOH421 |
| D | HOH425 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue EDO D 302 |
| Chain | Residue |
| D | PHE79 |
| D | ASP145 |
| D | HOH417 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO D 303 |
| Chain | Residue |
| D | ILE100 |
| D | ILE101 |
| D | LYS102 |
| D | THR103 |
| D | ASN135 |
| site_id | AC7 |
| Number of Residues | 13 |
| Details | binding site for residue YW7 E 301 |
| Chain | Residue |
| E | TRP81 |
| E | PRO82 |
| E | PHE83 |
| E | GLN85 |
| E | PRO86 |
| E | VAL87 |
| E | ASP88 |
| E | LEU92 |
| E | ASN140 |
| E | ILE146 |
| E | MET149 |
| E | HOH403 |
| E | HOH427 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue EDO E 302 |
| Chain | Residue |
| D | ASN116 |
| E | ILE100 |
| E | ILE101 |
| E | LYS102 |
| E | THR103 |
| E | ASN135 |
Functional Information from PROSITE/UniProt
| site_id | PS00633 |
| Number of Residues | 60 |
| Details | BROMODOMAIN_1 Bromodomain signature. AwpFqqpvDavklnlpDYYkiIktpMdmgtIkkrlenny..Ywnaqeciqdfnt.MftNCyiY |
| Chain | Residue | Details |
| A | ALA80-TYR139 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 424 |
| Details | Domain: {"description":"Bromo 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00035","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Site: {"description":"Acetylated histone binding","evidences":[{"source":"PubMed","id":"22464331","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]} |
