5RJQ

PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with NCL-00024665

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005158	molecular_function	insulin receptor binding
A	0008286	biological_process	insulin receptor signaling pathway

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	binding site for residue HHT A 1501

Chain	Residue
A	LEU1331
A	HOH1709
A	CYS1335
A	ASP1337
A	ARG1409
A	LEU1410
A	PHE1413
A	SER1423
A	ASP1424
A	HOH1682

---

site_id	AC2
Number of Residues	11
Details	binding site for residue HHT A 1502

Chain	Residue
A	PRO1340
A	PHE1341
A	VAL1345
A	TYR1350
A	SER1392
A	TYR1395
A	THR1396
A	ILE1403
A	HOH1602
A	HOH1605
A	HOH1613

---

Functional Information from PROSITE/UniProt

site_id	PS00633
Number of Residues	58
Details	BROMODOMAIN_1 Bromodomain signature. SepFrqpvDlleyp..DYRdiIdtpMdfatVretleagn..Yespmelckdvrl.IfsNSkaY

Chain	Residue	Details
A	SER1338-TYR1395

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	105
Details	Domain: {"description":"Bromo 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00035","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---