Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | binding site for residue RDV A 401 |
| Chain | Residue |
| A | ASP33 |
| A | ASP219 |
| A | GLY221 |
| A | THR222 |
| A | RDV402 |
| A | HOH536 |
| A | ASP35 |
| A | GLY37 |
| A | SER38 |
| A | ILE77 |
| A | TYR79 |
| A | GLY80 |
| A | PHE116 |
| A | LEU125 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | binding site for residue RDV A 402 |
| Chain | Residue |
| A | ASP15 |
| A | GLY80 |
| A | ASP81 |
| A | GLY221 |
| A | THR222 |
| A | THR223 |
| A | ILE300 |
| A | RDV401 |
| A | HOH502 |
| A | HOH573 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. LDFDTGSSDLWV |
| Chain | Residue | Details |
| A | LEU32-VAL43 | |
| A | GLY216-LEU227 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: |
| Chain | Residue | Details |
| A | ASP35 | |
| A | SER199 | |
