Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000184 | biological_process | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |
A | 0000290 | biological_process | deadenylation-dependent decapping of nuclear-transcribed mRNA |
A | 0016787 | molecular_function | hydrolase activity |
A | 0140933 | molecular_function | 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | binding site for residue EDO A 301 |
Chain | Residue |
A | ALA142 |
A | ASP152 |
A | HOH440 |
A | HOH448 |
site_id | AC2 |
Number of Residues | 6 |
Details | binding site for residue EDO A 302 |
Chain | Residue |
A | HOH449 |
A | PRO222 |
A | ASN223 |
A | LYS224 |
A | ACT305 |
A | HOH404 |
site_id | AC3 |
Number of Residues | 2 |
Details | binding site for residue DMS A 303 |
Chain | Residue |
A | ASN111 |
A | TRP199 |
site_id | AC4 |
Number of Residues | 3 |
Details | binding site for residue ACT A 304 |
Chain | Residue |
A | SER122 |
A | TYR156 |
A | HOH414 |
site_id | AC5 |
Number of Residues | 5 |
Details | binding site for residue ACT A 305 |
Chain | Residue |
A | ARG209 |
A | PRO222 |
A | ASN223 |
A | PHE226 |
A | EDO302 |
site_id | AC6 |
Number of Residues | 8 |
Details | binding site for residue PEG A 306 |
Chain | Residue |
A | VAL115 |
A | GLY117 |
A | LYS121 |
A | GLY123 |
A | GLY125 |
A | LYS128 |
A | GLU148 |
A | MET227 |
site_id | AC7 |
Number of Residues | 3 |
Details | binding site for residue JGD A 307 |
Chain | Residue |
A | PHE186 |
A | ASN196 |
A | ILE197 |
Functional Information from PROSITE/UniProt
site_id | PS00893 |
Number of Residues | 22 |
Details | NUDIX_BOX Nudix box signature. GkvnkeEaphdCAaREVfEEtG |
Chain | Residue | Details |
A | GLY129-GLY150 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | BINDING: BINDING => ECO:0000250 |
Chain | Residue | Details |
A | GLU144 | |
A | GLU148 | |
Chain | Residue | Details |
A | SER246 | |
A | SER247 | |
Chain | Residue | Details |
A | SER249 | |