Functional Information from GO Data
| Chain | GOid | namespace | contents |
| D | 0004252 | molecular_function | serine-type endopeptidase activity |
| D | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 301 |
| Chain | Residue |
| A | PRO189 |
| A | THR190 |
| A | VAL191 |
| A | HOH411 |
| A | HOH426 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 302 |
| Chain | Residue |
| D | TRP416 |
| D | GOL506 |
| D | HOH607 |
| D | HOH752 |
| A | LYS197 |
| A | ILE198 |
| A | LEU201 |
| A | GLU202 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 303 |
| Chain | Residue |
| A | CYS174 |
| A | SER179 |
| A | LEU180 |
| A | HOH413 |
| D | GLU454 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue CA D 501 |
| Chain | Residue |
| D | GLU270 |
| D | ASP272 |
| D | GLU275 |
| D | GLU280 |
| D | HOH634 |
| D | HOH829 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 D 502 |
| Chain | Residue |
| D | ARG283 |
| D | ARG284 |
| D | HIS309 |
| D | GLN310 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 D 503 |
| Chain | Residue |
| D | THR315 |
| D | ASP316 |
| D | HIS317 |
| D | HOH740 |
| D | HOH763 |
| D | HOH797 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 D 504 |
| Chain | Residue |
| D | MET366 |
| D | THR367 |
| D | ARG439 |
| D | HOH630 |
| D | HOH712 |
| D | HOH733 |
| D | HOH826 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 D 505 |
| Chain | Residue |
| D | GLN281 |
| D | VAL313 |
| D | THR315 |
| D | HOH655 |
| D | HOH734 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | binding site for residue GOL D 506 |
| Chain | Residue |
| A | ILE198 |
| A | GOL302 |
| D | LYS217 |
| D | GLU223 |
| D | LEU340 |
| D | TRP416 |
| D | HOH608 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue GOL D 507 |
| Chain | Residue |
| D | SER374 |
| D | TRP424 |
| D | GLN426 |
| D | HIS433 |
| D | PHE434 |
| site_id | AD2 |
| Number of Residues | 10 |
| Details | binding site for residue BEN D 508 |
| Chain | Residue |
| D | ASP398 |
| D | SER399 |
| D | SER404 |
| D | VAL422 |
| D | SER423 |
| D | TRP424 |
| D | GLY425 |
| D | GLY427 |
| D | GLY435 |
| D | HOH700 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 D 509 |
| Chain | Residue |
| D | HIS253 |
| D | LYS401 |
| D | GLY402 |
| D | SER404 |
| D | HOH690 |
| D | HOH739 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
| Chain | Residue | Details |
| D | VAL249-CYS254 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DSckGDSGGPHA |
| Chain | Residue | Details |
| D | ASP398-ALA409 | |
| site_id | PS01186 |
| Number of Residues | 16 |
| Details | EGF_2 EGF-like domain signature 2. CrCheGYslladgvsC |
| Chain | Residue | Details |
| A | CYS172-CYS187 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Charge relay system","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19167329","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"3264725","evidenceCode":"ECO:0000269"}]} |
