5OXH

C-terminally retracted ubiquitin T66V/L67N mutant

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue SO4 A 101

Chain	Residue
A	THR12
A	ILE13
A	THR14
A	ARG54
A	HOH219
A	HOH225
A	HOH287

---

site_id	AC2
Number of Residues	5
Details	binding site for residue SO4 A 102

Chain	Residue
A	GLY75
A	HOH205
A	HOH291
A	ARG42
A	ARG74

---

site_id	AC3
Number of Residues	3
Details	binding site for residue SO4 A 103

Chain	Residue
A	ARG42
A	ARG72
A	HOH204

---

site_id	AC4
Number of Residues	3
Details	binding site for residue SO4 A 104

Chain	Residue
A	GLN49
A	ARG74
A	HOH264

---

site_id	AC5
Number of Residues	6
Details	binding site for residue SO4 A 105

Chain	Residue
A	GLU51
A	ARG54
A	HOH207
A	HOH213
A	HOH223
A	HOH292

---

site_id	AC6
Number of Residues	6
Details	binding site for residue SO4 A 106

Chain	Residue
A	LYS33
A	ASN60
A	LYS63
A	HOH228
A	HOH279
A	HOH300

---

site_id	AC7
Number of Residues	6
Details	binding site for residue SO4 A 107

Chain	Residue
A	SER20
A	ARG72
A	HOH248
A	HOH260
A	HOH271
A	HOH273

---

site_id	AC8
Number of Residues	8
Details	binding site for residue SO4 A 108

Chain	Residue
A	LYS6
A	ASP21
A	THR22
A	ASN25
A	HOH201
A	HOH203
A	HOH239
A	HOH249

---

Functional Information from PROSITE/UniProt

site_id	PS00299
Number of Residues	26
Details	UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD

Chain	Residue	Details
A	LYS27-ASP52

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	SITE: Interacts with activating enzyme

Chain	Residue	Details
A	ARG54
A	ARG72

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	SITE: Essential for function

Chain	Residue	Details
A	HIS68

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphoserine; by PINK1 => ECO:0000269|PubMed:24660806, ECO:0000269|PubMed:24751536, ECO:0000269|PubMed:24784582, ECO:0000269|PubMed:25527291

Chain	Residue	Details
A	SEP65

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: (Microbial infection) ADP-ribosylthreonine => ECO:0000269|PubMed:32330457

Chain	Residue	Details
A	VAL66

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: ADP-ribosylglycine => ECO:0000269|PubMed:28525742

Chain	Residue	Details
A	GLY76

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16443603

Chain	Residue	Details
A	LYS6

---

site_id	SWS_FT_FI7
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)

Chain	Residue	Details
A	GLY76

---

site_id	SWS_FT_FI8
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16443603, ECO:0000269|PubMed:16543144

Chain	Residue	Details
A	LYS11
A	LYS48

---

site_id	SWS_FT_FI9
Number of Residues	1
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000305|PubMed:15466860

Chain	Residue	Details
A	LYS27

---

site_id	SWS_FT_FI10
Number of Residues	1
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16543144, ECO:0000269|PubMed:25752573, ECO:0000269|PubMed:25752577, ECO:0000269|PubMed:34239127

Chain	Residue	Details
A	LYS29

---

site_id	SWS_FT_FI11
Number of Residues	1
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:25752577

Chain	Residue	Details
A	LYS33

---

site_id	SWS_FT_FI12
Number of Residues	1
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16543144, ECO:0000269|PubMed:18719106

Chain	Residue	Details
A	LYS63

---