5OXD
Complex of a C. perfringens O-GlcNAcase with a fragment hit
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue CD A 701 |
| Chain | Residue |
| A | GLU51 |
| A | ASN450 |
| A | ASP452 |
| A | HOH823 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue CD A 702 |
| Chain | Residue |
| A | ASP58 |
| A | GLU272 |
| A | CD710 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue CD A 703 |
| Chain | Residue |
| A | LEU68 |
| A | GLU71 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue CD A 704 |
| Chain | Residue |
| A | GLU73 |
| A | GLU108 |
| A | ASP111 |
| A | HOH811 |
| A | HOH838 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue CD A 705 |
| Chain | Residue |
| A | ASP112 |
| A | ASP197 |
| A | GLU550 |
| A | CD722 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue CD A 706 |
| Chain | Residue |
| A | ASP117 |
| A | THR124 |
| A | GLU145 |
| A | GLU545 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue CD A 707 |
| Chain | Residue |
| A | ASP268 |
| A | HOH808 |
| A | HOH843 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue CD A 708 |
| Chain | Residue |
| A | ASP150 |
| A | ASP252 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue CD A 709 |
| Chain | Residue |
| A | GLU170 |
| A | HOH801 |
| A | HOH831 |
| A | HOH851 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue CD A 710 |
| Chain | Residue |
| A | ARG264 |
| A | GLU272 |
| A | HIS276 |
| A | CD702 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue CD A 711 |
| Chain | Residue |
| A | GLU282 |
| A | ASP286 |
| A | GLU588 |
| A | HOH810 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue CD A 712 |
| Chain | Residue |
| A | GLU362 |
| A | HOH824 |
| A | HOH862 |
| site_id | AD4 |
| Number of Residues | 1 |
| Details | binding site for residue CD A 713 |
| Chain | Residue |
| A | ASP388 |
| site_id | AD5 |
| Number of Residues | 1 |
| Details | binding site for residue CD A 714 |
| Chain | Residue |
| A | HIS413 |
| site_id | AD6 |
| Number of Residues | 2 |
| Details | binding site for residue CD A 715 |
| Chain | Residue |
| A | ASP474 |
| A | ARG531 |
| site_id | AD7 |
| Number of Residues | 2 |
| Details | binding site for residue CD A 716 |
| Chain | Residue |
| A | ASP457 |
| A | ASN461 |
| site_id | AD8 |
| Number of Residues | 5 |
| Details | binding site for residue CD A 717 |
| Chain | Residue |
| A | ASP117 |
| A | GLU545 |
| A | GLU549 |
| A | CD719 |
| A | HOH844 |
| site_id | AD9 |
| Number of Residues | 1 |
| Details | binding site for residue CD A 718 |
| Chain | Residue |
| A | ASP401 |
| site_id | AE1 |
| Number of Residues | 7 |
| Details | binding site for residue CD A 719 |
| Chain | Residue |
| A | GLU108 |
| A | VAL109 |
| A | ASP111 |
| A | GLU145 |
| A | GLU545 |
| A | GLU549 |
| A | CD717 |
| site_id | AE2 |
| Number of Residues | 4 |
| Details | binding site for residue CD A 722 |
| Chain | Residue |
| A | ASP112 |
| A | GLU550 |
| A | CD705 |
| A | HOH803 |
| site_id | AE3 |
| Number of Residues | 2 |
| Details | binding site for residue B2W A 723 |
| Chain | Residue |
| A | TYR189 |
| A | ASP401 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 272 |
| Details | Domain: {"description":"GH84","evidences":[{"source":"PROSITE-ProRule","id":"PRU01353","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 290 |
| Details | Region: {"description":"Catalytic domain","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 52 |
| Details | Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"PROSITE-ProRule","id":"PRU01353","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16541109","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16541109","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
