5OVJ
Structure of the apo form of Mycobacterium smegmatis MabA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004316 | molecular_function | 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0006631 | biological_process | fatty acid metabolic process |
| A | 0006633 | biological_process | fatty acid biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0018454 | molecular_function | acetoacetyl-CoA reductase activity |
| A | 0030497 | biological_process | fatty acid elongation |
| A | 0032787 | biological_process | monocarboxylic acid metabolic process |
| A | 0050661 | molecular_function | NADP binding |
| B | 0004316 | molecular_function | 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity |
| B | 0005576 | cellular_component | extracellular region |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0006631 | biological_process | fatty acid metabolic process |
| B | 0006633 | biological_process | fatty acid biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0018454 | molecular_function | acetoacetyl-CoA reductase activity |
| B | 0030497 | biological_process | fatty acid elongation |
| B | 0032787 | biological_process | monocarboxylic acid metabolic process |
| B | 0050661 | molecular_function | NADP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 301 |
| Chain | Residue |
| A | THR109 |
| A | ARG112 |
| A | HOH409 |
| A | HOH491 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 302 |
| Chain | Residue |
| A | HOH545 |
| B | HOH408 |
| A | ASN32 |
| A | ARG33 |
| A | ARG55 |
| A | GLY56 |
| A | SER57 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 303 |
| Chain | Residue |
| A | THR109 |
| A | GLU110 |
| A | GLU111 |
| A | HOH405 |
| A | HOH416 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 304 |
| Chain | Residue |
| A | ARG18 |
| A | PRO19 |
| A | HOH440 |
| B | ARG18 |
| B | HOH492 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 B 301 |
| Chain | Residue |
| B | ASN32 |
| B | ARG33 |
| B | HIS54 |
| B | ARG55 |
| B | GLY56 |
| B | SER57 |
| B | HOH416 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 302 |
| Chain | Residue |
| A | ARG200 |
| B | ARG78 |
| B | HOH463 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 303 |
| Chain | Residue |
| B | THR109 |
| B | ARG112 |
| B | HOH402 |
Functional Information from PROSITE/UniProt
| site_id | PS00061 |
| Number of Residues | 29 |
| Details | ADH_SHORT Short-chain dehydrogenases/reductases family signature. SvsgmwgignQanYAAAKAGLiGMArSIS |
| Chain | Residue | Details |
| A | SER148-SER176 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU10001","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"29717709","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P9WGT3","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Site: {"description":"Important for activity","evidences":[{"source":"UniProtKB","id":"P9WGT3","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
