Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004672 | molecular_function | protein kinase activity |
A | 0004674 | molecular_function | protein serine/threonine kinase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0006468 | biological_process | protein phosphorylation |
B | 0004672 | molecular_function | protein kinase activity |
B | 0004674 | molecular_function | protein serine/threonine kinase activity |
B | 0005524 | molecular_function | ATP binding |
B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 3 |
Details | binding site for residue MG B 401 |
Chain | Residue |
B | ASN161 |
B | ASP175 |
B | ADP403 |
site_id | AC2 |
Number of Residues | 3 |
Details | binding site for residue MG B 402 |
Chain | Residue |
B | PHE113 |
B | ASP175 |
B | ADP403 |
site_id | AC3 |
Number of Residues | 16 |
Details | binding site for residue ADP B 403 |
Chain | Residue |
B | SER51 |
B | VAL53 |
B | VAL66 |
B | LYS68 |
B | ILE95 |
B | GLU114 |
B | VAL116 |
B | HIS160 |
B | ASN161 |
B | ILE174 |
B | ASP175 |
B | MG401 |
B | MG402 |
B | GLY48 |
B | LYS49 |
B | TYR50 |
site_id | AC4 |
Number of Residues | 7 |
Details | binding site for residue A4Q B 404 |
Chain | Residue |
B | PHE121 |
B | ILE140 |
B | PRO159 |
B | VAL162 |
B | MET221 |
B | MET225 |
B | HOH526 |
site_id | AC5 |
Number of Residues | 3 |
Details | binding site for residue MG A 401 |
Chain | Residue |
A | ASP175 |
A | ADP404 |
A | HOH501 |
site_id | AC6 |
Number of Residues | 5 |
Details | binding site for residue MG A 402 |
Chain | Residue |
A | TYR50 |
A | LYS77 |
A | ASP175 |
A | GLY177 |
A | ADP404 |
site_id | AC7 |
Number of Residues | 3 |
Details | binding site for residue MG A 403 |
Chain | Residue |
A | ASN161 |
A | ASP175 |
A | ADP404 |
site_id | AC8 |
Number of Residues | 18 |
Details | binding site for residue ADP A 404 |
Chain | Residue |
A | GLY48 |
A | LYS49 |
A | TYR50 |
A | SER51 |
A | VAL53 |
A | VAL66 |
A | LYS68 |
A | ILE95 |
A | GLU114 |
A | VAL116 |
A | HIS160 |
A | ASN161 |
A | MET163 |
A | ILE174 |
A | ASP175 |
A | MG401 |
A | MG402 |
A | MG403 |
site_id | AC9 |
Number of Residues | 8 |
Details | binding site for residue A4Q A 405 |
Chain | Residue |
A | ASN118 |
A | PHE121 |
A | ILE140 |
A | PRO159 |
A | VAL162 |
A | ILE164 |
A | MET221 |
A | MET225 |
site_id | AD1 |
Number of Residues | 8 |
Details | binding site for residue A4Q A 406 |
Chain | Residue |
A | GLN36 |
A | ASP37 |
A | TYR39 |
A | ILE69 |
A | ASP103 |
A | THR108 |
A | ALA110 |
A | HOH526 |
site_id | AD2 |
Number of Residues | 4 |
Details | binding site for residue IHP A 407 |
Chain | Residue |
A | LYS229 |
A | HIS234 |
A | HIS236 |
A | ARG244 |
Functional Information from PROSITE/UniProt
site_id | PS00107 |
Number of Residues | 24 |
Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGRGKYSEVFeAinitnnek..........VVVK |
Chain | Residue | Details |
B | LEU45-LYS68 | |
site_id | PS00108 |
Number of Residues | 13 |
Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. ImHrDVKphNVMI |
Chain | Residue | Details |
B | ILE152-ILE164 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: Proton acceptor |
Chain | Residue | Details |
B | ASP156 | |
A | ASP156 | |
Chain | Residue | Details |
B | LEU45 | |
B | LYS68 | |
A | LEU45 | |
A | LYS68 | |