5OPX

Crystal structure of the GroEL mutant A109C in complex with GroES and ADP BeF2

Functional Information from GO Data

Chain	GOid	namespace	contents
1	0005515	molecular_function	protein binding
1	0005524	molecular_function	ATP binding
1	0005737	cellular_component	cytoplasm
1	0005829	cellular_component	cytosol
1	0006457	biological_process	protein folding
1	0009408	biological_process	response to heat
1	0019068	biological_process	virion assembly
1	0042802	molecular_function	identical protein binding
1	0044183	molecular_function	protein folding chaperone
1	0046872	molecular_function	metal ion binding
1	0051082	molecular_function	unfolded protein binding
1	0051085	biological_process	chaperone cofactor-dependent protein refolding
1	0051087	molecular_function	protein-folding chaperone binding
1	1990220	cellular_component	GroEL-GroES complex
2	0005515	molecular_function	protein binding
2	0005524	molecular_function	ATP binding
2	0005737	cellular_component	cytoplasm
2	0005829	cellular_component	cytosol
2	0006457	biological_process	protein folding
2	0009408	biological_process	response to heat
2	0019068	biological_process	virion assembly
2	0042802	molecular_function	identical protein binding
2	0044183	molecular_function	protein folding chaperone
2	0046872	molecular_function	metal ion binding
2	0051082	molecular_function	unfolded protein binding
2	0051085	biological_process	chaperone cofactor-dependent protein refolding
2	0051087	molecular_function	protein-folding chaperone binding
2	1990220	cellular_component	GroEL-GroES complex
A	0000287	molecular_function	magnesium ion binding
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006457	biological_process	protein folding
A	0009314	biological_process	response to radiation
A	0009408	biological_process	response to heat
A	0016020	cellular_component	membrane
A	0016853	molecular_function	isomerase activity
A	0016887	molecular_function	ATP hydrolysis activity
A	0019068	biological_process	virion assembly
A	0042026	biological_process	protein refolding
A	0042802	molecular_function	identical protein binding
A	0051082	molecular_function	unfolded protein binding
A	0051085	biological_process	chaperone cofactor-dependent protein refolding
A	0140662	molecular_function	ATP-dependent protein folding chaperone
A	1990220	cellular_component	GroEL-GroES complex
B	0000287	molecular_function	magnesium ion binding
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006457	biological_process	protein folding
B	0009314	biological_process	response to radiation
B	0009408	biological_process	response to heat
B	0016020	cellular_component	membrane
B	0016853	molecular_function	isomerase activity
B	0016887	molecular_function	ATP hydrolysis activity
B	0019068	biological_process	virion assembly
B	0042026	biological_process	protein refolding
B	0042802	molecular_function	identical protein binding
B	0051082	molecular_function	unfolded protein binding
B	0051085	biological_process	chaperone cofactor-dependent protein refolding
B	0140662	molecular_function	ATP-dependent protein folding chaperone
B	1990220	cellular_component	GroEL-GroES complex
C	0000287	molecular_function	magnesium ion binding
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006457	biological_process	protein folding
C	0009314	biological_process	response to radiation
C	0009408	biological_process	response to heat
C	0016020	cellular_component	membrane
C	0016853	molecular_function	isomerase activity
C	0016887	molecular_function	ATP hydrolysis activity
C	0019068	biological_process	virion assembly
C	0042026	biological_process	protein refolding
C	0042802	molecular_function	identical protein binding
C	0051082	molecular_function	unfolded protein binding
C	0051085	biological_process	chaperone cofactor-dependent protein refolding
C	0140662	molecular_function	ATP-dependent protein folding chaperone
C	1990220	cellular_component	GroEL-GroES complex
D	0000287	molecular_function	magnesium ion binding
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006457	biological_process	protein folding
D	0009314	biological_process	response to radiation
D	0009408	biological_process	response to heat
D	0016020	cellular_component	membrane
D	0016853	molecular_function	isomerase activity
D	0016887	molecular_function	ATP hydrolysis activity
D	0019068	biological_process	virion assembly
D	0042026	biological_process	protein refolding
D	0042802	molecular_function	identical protein binding
D	0051082	molecular_function	unfolded protein binding
D	0051085	biological_process	chaperone cofactor-dependent protein refolding
D	0140662	molecular_function	ATP-dependent protein folding chaperone
D	1990220	cellular_component	GroEL-GroES complex
E	0000287	molecular_function	magnesium ion binding
E	0005515	molecular_function	protein binding
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0006457	biological_process	protein folding
E	0009314	biological_process	response to radiation
E	0009408	biological_process	response to heat
E	0016020	cellular_component	membrane
E	0016853	molecular_function	isomerase activity
E	0016887	molecular_function	ATP hydrolysis activity
E	0019068	biological_process	virion assembly
E	0042026	biological_process	protein refolding
E	0042802	molecular_function	identical protein binding
E	0051082	molecular_function	unfolded protein binding
E	0051085	biological_process	chaperone cofactor-dependent protein refolding
E	0140662	molecular_function	ATP-dependent protein folding chaperone
E	1990220	cellular_component	GroEL-GroES complex
F	0000287	molecular_function	magnesium ion binding
F	0005515	molecular_function	protein binding
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0006457	biological_process	protein folding
F	0009314	biological_process	response to radiation
F	0009408	biological_process	response to heat
F	0016020	cellular_component	membrane
F	0016853	molecular_function	isomerase activity
F	0016887	molecular_function	ATP hydrolysis activity
F	0019068	biological_process	virion assembly
F	0042026	biological_process	protein refolding
F	0042802	molecular_function	identical protein binding
F	0051082	molecular_function	unfolded protein binding
F	0051085	biological_process	chaperone cofactor-dependent protein refolding
F	0140662	molecular_function	ATP-dependent protein folding chaperone
F	1990220	cellular_component	GroEL-GroES complex
G	0000287	molecular_function	magnesium ion binding
G	0005515	molecular_function	protein binding
G	0005524	molecular_function	ATP binding
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0006457	biological_process	protein folding
G	0009314	biological_process	response to radiation
G	0009408	biological_process	response to heat
G	0016020	cellular_component	membrane
G	0016853	molecular_function	isomerase activity
G	0016887	molecular_function	ATP hydrolysis activity
G	0019068	biological_process	virion assembly
G	0042026	biological_process	protein refolding
G	0042802	molecular_function	identical protein binding
G	0051082	molecular_function	unfolded protein binding
G	0051085	biological_process	chaperone cofactor-dependent protein refolding
G	0140662	molecular_function	ATP-dependent protein folding chaperone
G	1990220	cellular_component	GroEL-GroES complex
H	0000287	molecular_function	magnesium ion binding
H	0005515	molecular_function	protein binding
H	0005524	molecular_function	ATP binding
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0006457	biological_process	protein folding
H	0009314	biological_process	response to radiation
H	0009408	biological_process	response to heat
H	0016020	cellular_component	membrane
H	0016853	molecular_function	isomerase activity
H	0016887	molecular_function	ATP hydrolysis activity
H	0019068	biological_process	virion assembly
H	0042026	biological_process	protein refolding
H	0042802	molecular_function	identical protein binding
H	0051082	molecular_function	unfolded protein binding
H	0051085	biological_process	chaperone cofactor-dependent protein refolding
H	0140662	molecular_function	ATP-dependent protein folding chaperone
H	1990220	cellular_component	GroEL-GroES complex
I	0000287	molecular_function	magnesium ion binding
I	0005515	molecular_function	protein binding
I	0005524	molecular_function	ATP binding
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0006457	biological_process	protein folding
I	0009314	biological_process	response to radiation
I	0009408	biological_process	response to heat
I	0016020	cellular_component	membrane
I	0016853	molecular_function	isomerase activity
I	0016887	molecular_function	ATP hydrolysis activity
I	0019068	biological_process	virion assembly
I	0042026	biological_process	protein refolding
I	0042802	molecular_function	identical protein binding
I	0051082	molecular_function	unfolded protein binding
I	0051085	biological_process	chaperone cofactor-dependent protein refolding
I	0140662	molecular_function	ATP-dependent protein folding chaperone
I	1990220	cellular_component	GroEL-GroES complex
J	0000287	molecular_function	magnesium ion binding
J	0005515	molecular_function	protein binding
J	0005524	molecular_function	ATP binding
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0006457	biological_process	protein folding
J	0009314	biological_process	response to radiation
J	0009408	biological_process	response to heat
J	0016020	cellular_component	membrane
J	0016853	molecular_function	isomerase activity
J	0016887	molecular_function	ATP hydrolysis activity
J	0019068	biological_process	virion assembly
J	0042026	biological_process	protein refolding
J	0042802	molecular_function	identical protein binding
J	0051082	molecular_function	unfolded protein binding
J	0051085	biological_process	chaperone cofactor-dependent protein refolding
J	0140662	molecular_function	ATP-dependent protein folding chaperone
J	1990220	cellular_component	GroEL-GroES complex
K	0000287	molecular_function	magnesium ion binding
K	0005515	molecular_function	protein binding
K	0005524	molecular_function	ATP binding
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0006457	biological_process	protein folding
K	0009314	biological_process	response to radiation
K	0009408	biological_process	response to heat
K	0016020	cellular_component	membrane
K	0016853	molecular_function	isomerase activity
K	0016887	molecular_function	ATP hydrolysis activity
K	0019068	biological_process	virion assembly
K	0042026	biological_process	protein refolding
K	0042802	molecular_function	identical protein binding
K	0051082	molecular_function	unfolded protein binding
K	0051085	biological_process	chaperone cofactor-dependent protein refolding
K	0140662	molecular_function	ATP-dependent protein folding chaperone
K	1990220	cellular_component	GroEL-GroES complex
L	0000287	molecular_function	magnesium ion binding
L	0005515	molecular_function	protein binding
L	0005524	molecular_function	ATP binding
L	0005737	cellular_component	cytoplasm
L	0005829	cellular_component	cytosol
L	0006457	biological_process	protein folding
L	0009314	biological_process	response to radiation
L	0009408	biological_process	response to heat
L	0016020	cellular_component	membrane
L	0016853	molecular_function	isomerase activity
L	0016887	molecular_function	ATP hydrolysis activity
L	0019068	biological_process	virion assembly
L	0042026	biological_process	protein refolding
L	0042802	molecular_function	identical protein binding
L	0051082	molecular_function	unfolded protein binding
L	0051085	biological_process	chaperone cofactor-dependent protein refolding
L	0140662	molecular_function	ATP-dependent protein folding chaperone
L	1990220	cellular_component	GroEL-GroES complex
M	0000287	molecular_function	magnesium ion binding
M	0005515	molecular_function	protein binding
M	0005524	molecular_function	ATP binding
M	0005737	cellular_component	cytoplasm
M	0005829	cellular_component	cytosol
M	0006457	biological_process	protein folding
M	0009314	biological_process	response to radiation
M	0009408	biological_process	response to heat
M	0016020	cellular_component	membrane
M	0016853	molecular_function	isomerase activity
M	0016887	molecular_function	ATP hydrolysis activity
M	0019068	biological_process	virion assembly
M	0042026	biological_process	protein refolding
M	0042802	molecular_function	identical protein binding
M	0051082	molecular_function	unfolded protein binding
M	0051085	biological_process	chaperone cofactor-dependent protein refolding
M	0140662	molecular_function	ATP-dependent protein folding chaperone
M	1990220	cellular_component	GroEL-GroES complex
N	0000287	molecular_function	magnesium ion binding
N	0005515	molecular_function	protein binding
N	0005524	molecular_function	ATP binding
N	0005737	cellular_component	cytoplasm
N	0005829	cellular_component	cytosol
N	0006457	biological_process	protein folding
N	0009314	biological_process	response to radiation
N	0009408	biological_process	response to heat
N	0016020	cellular_component	membrane
N	0016853	molecular_function	isomerase activity
N	0016887	molecular_function	ATP hydrolysis activity
N	0019068	biological_process	virion assembly
N	0042026	biological_process	protein refolding
N	0042802	molecular_function	identical protein binding
N	0051082	molecular_function	unfolded protein binding
N	0051085	biological_process	chaperone cofactor-dependent protein refolding
N	0140662	molecular_function	ATP-dependent protein folding chaperone
N	1990220	cellular_component	GroEL-GroES complex
O	0005515	molecular_function	protein binding
O	0005524	molecular_function	ATP binding
O	0005737	cellular_component	cytoplasm
O	0005829	cellular_component	cytosol
O	0006457	biological_process	protein folding
O	0009408	biological_process	response to heat
O	0019068	biological_process	virion assembly
O	0042802	molecular_function	identical protein binding
O	0044183	molecular_function	protein folding chaperone
O	0046872	molecular_function	metal ion binding
O	0051082	molecular_function	unfolded protein binding
O	0051085	biological_process	chaperone cofactor-dependent protein refolding
O	0051087	molecular_function	protein-folding chaperone binding
O	1990220	cellular_component	GroEL-GroES complex
P	0005515	molecular_function	protein binding
P	0005524	molecular_function	ATP binding
P	0005737	cellular_component	cytoplasm
P	0005829	cellular_component	cytosol
P	0006457	biological_process	protein folding
P	0009408	biological_process	response to heat
P	0019068	biological_process	virion assembly
P	0042802	molecular_function	identical protein binding
P	0044183	molecular_function	protein folding chaperone
P	0046872	molecular_function	metal ion binding
P	0051082	molecular_function	unfolded protein binding
P	0051085	biological_process	chaperone cofactor-dependent protein refolding
P	0051087	molecular_function	protein-folding chaperone binding
P	1990220	cellular_component	GroEL-GroES complex
Q	0005515	molecular_function	protein binding
Q	0005524	molecular_function	ATP binding
Q	0005737	cellular_component	cytoplasm
Q	0005829	cellular_component	cytosol
Q	0006457	biological_process	protein folding
Q	0009408	biological_process	response to heat
Q	0019068	biological_process	virion assembly
Q	0042802	molecular_function	identical protein binding
Q	0044183	molecular_function	protein folding chaperone
Q	0046872	molecular_function	metal ion binding
Q	0051082	molecular_function	unfolded protein binding
Q	0051085	biological_process	chaperone cofactor-dependent protein refolding
Q	0051087	molecular_function	protein-folding chaperone binding
Q	1990220	cellular_component	GroEL-GroES complex
R	0005515	molecular_function	protein binding
R	0005524	molecular_function	ATP binding
R	0005737	cellular_component	cytoplasm
R	0005829	cellular_component	cytosol
R	0006457	biological_process	protein folding
R	0009408	biological_process	response to heat
R	0019068	biological_process	virion assembly
R	0042802	molecular_function	identical protein binding
R	0044183	molecular_function	protein folding chaperone
R	0046872	molecular_function	metal ion binding
R	0051082	molecular_function	unfolded protein binding
R	0051085	biological_process	chaperone cofactor-dependent protein refolding
R	0051087	molecular_function	protein-folding chaperone binding
R	1990220	cellular_component	GroEL-GroES complex
S	0005515	molecular_function	protein binding
S	0005524	molecular_function	ATP binding
S	0005737	cellular_component	cytoplasm
S	0005829	cellular_component	cytosol
S	0006457	biological_process	protein folding
S	0009408	biological_process	response to heat
S	0019068	biological_process	virion assembly
S	0042802	molecular_function	identical protein binding
S	0044183	molecular_function	protein folding chaperone
S	0046872	molecular_function	metal ion binding
S	0051082	molecular_function	unfolded protein binding
S	0051085	biological_process	chaperone cofactor-dependent protein refolding
S	0051087	molecular_function	protein-folding chaperone binding
S	1990220	cellular_component	GroEL-GroES complex
T	0005515	molecular_function	protein binding
T	0005524	molecular_function	ATP binding
T	0005737	cellular_component	cytoplasm
T	0005829	cellular_component	cytosol
T	0006457	biological_process	protein folding
T	0009408	biological_process	response to heat
T	0019068	biological_process	virion assembly
T	0042802	molecular_function	identical protein binding
T	0044183	molecular_function	protein folding chaperone
T	0046872	molecular_function	metal ion binding
T	0051082	molecular_function	unfolded protein binding
T	0051085	biological_process	chaperone cofactor-dependent protein refolding
T	0051087	molecular_function	protein-folding chaperone binding
T	1990220	cellular_component	GroEL-GroES complex
U	0005515	molecular_function	protein binding
U	0005524	molecular_function	ATP binding
U	0005737	cellular_component	cytoplasm
U	0005829	cellular_component	cytosol
U	0006457	biological_process	protein folding
U	0009408	biological_process	response to heat
U	0019068	biological_process	virion assembly
U	0042802	molecular_function	identical protein binding
U	0044183	molecular_function	protein folding chaperone
U	0046872	molecular_function	metal ion binding
U	0051082	molecular_function	unfolded protein binding
U	0051085	biological_process	chaperone cofactor-dependent protein refolding
U	0051087	molecular_function	protein-folding chaperone binding
U	1990220	cellular_component	GroEL-GroES complex
V	0005515	molecular_function	protein binding
V	0005524	molecular_function	ATP binding
V	0005737	cellular_component	cytoplasm
V	0005829	cellular_component	cytosol
V	0006457	biological_process	protein folding
V	0009408	biological_process	response to heat
V	0019068	biological_process	virion assembly
V	0042802	molecular_function	identical protein binding
V	0044183	molecular_function	protein folding chaperone
V	0046872	molecular_function	metal ion binding
V	0051082	molecular_function	unfolded protein binding
V	0051085	biological_process	chaperone cofactor-dependent protein refolding
V	0051087	molecular_function	protein-folding chaperone binding
V	1990220	cellular_component	GroEL-GroES complex
W	0005515	molecular_function	protein binding
W	0005524	molecular_function	ATP binding
W	0005737	cellular_component	cytoplasm
W	0005829	cellular_component	cytosol
W	0006457	biological_process	protein folding
W	0009408	biological_process	response to heat
W	0019068	biological_process	virion assembly
W	0042802	molecular_function	identical protein binding
W	0044183	molecular_function	protein folding chaperone
W	0046872	molecular_function	metal ion binding
W	0051082	molecular_function	unfolded protein binding
W	0051085	biological_process	chaperone cofactor-dependent protein refolding
W	0051087	molecular_function	protein-folding chaperone binding
W	1990220	cellular_component	GroEL-GroES complex
X	0005515	molecular_function	protein binding
X	0005524	molecular_function	ATP binding
X	0005737	cellular_component	cytoplasm
X	0005829	cellular_component	cytosol
X	0006457	biological_process	protein folding
X	0009408	biological_process	response to heat
X	0019068	biological_process	virion assembly
X	0042802	molecular_function	identical protein binding
X	0044183	molecular_function	protein folding chaperone
X	0046872	molecular_function	metal ion binding
X	0051082	molecular_function	unfolded protein binding
X	0051085	biological_process	chaperone cofactor-dependent protein refolding
X	0051087	molecular_function	protein-folding chaperone binding
X	1990220	cellular_component	GroEL-GroES complex
Y	0005515	molecular_function	protein binding
Y	0005524	molecular_function	ATP binding
Y	0005737	cellular_component	cytoplasm
Y	0005829	cellular_component	cytosol
Y	0006457	biological_process	protein folding
Y	0009408	biological_process	response to heat
Y	0019068	biological_process	virion assembly
Y	0042802	molecular_function	identical protein binding
Y	0044183	molecular_function	protein folding chaperone
Y	0046872	molecular_function	metal ion binding
Y	0051082	molecular_function	unfolded protein binding
Y	0051085	biological_process	chaperone cofactor-dependent protein refolding
Y	0051087	molecular_function	protein-folding chaperone binding
Y	1990220	cellular_component	GroEL-GroES complex
Z	0005515	molecular_function	protein binding
Z	0005524	molecular_function	ATP binding
Z	0005737	cellular_component	cytoplasm
Z	0005829	cellular_component	cytosol
Z	0006457	biological_process	protein folding
Z	0009408	biological_process	response to heat
Z	0019068	biological_process	virion assembly
Z	0042802	molecular_function	identical protein binding
Z	0044183	molecular_function	protein folding chaperone
Z	0046872	molecular_function	metal ion binding
Z	0051082	molecular_function	unfolded protein binding
Z	0051085	biological_process	chaperone cofactor-dependent protein refolding
Z	0051087	molecular_function	protein-folding chaperone binding
Z	1990220	cellular_component	GroEL-GroES complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	22
Details	binding site for residue ADP A 600

Chain	Residue
A	THR30
A	THR91
A	ILE150
A	GLY414
A	GLY415
A	ILE454
A	TYR478
A	ASN479
A	ALA480
A	ALA481
A	ASP495
A	LEU31
A	MG601
A	BEF602
A	K603
A	GLY32
A	PRO33
A	LYS51
A	ASP87
A	GLY88
A	THR89
A	THR90

---

site_id	AC2
Number of Residues	3
Details	binding site for residue MG A 601

Chain	Residue
A	ASP87
A	ADP600
A	BEF602

---

site_id	AC3
Number of Residues	9
Details	binding site for residue BEF A 602

Chain	Residue
A	ASP52
A	GLY53
A	ASP87
A	THR89
A	THR90
A	ASP398
A	ADP600
A	MG601
A	K603

---

site_id	AC4
Number of Residues	5
Details	binding site for residue K A 603

Chain	Residue
A	THR30
A	LYS51
A	THR90
A	ADP600
A	BEF602

---

site_id	AC5
Number of Residues	22
Details	binding site for residue ADP B 600

Chain	Residue
B	THR30
B	LEU31
B	GLY32
B	PRO33
B	LYS51
B	ASP87
B	GLY88
B	THR89
B	THR90
B	THR91
B	ILE150
B	GLY414
B	GLY415
B	ILE454
B	TYR478
B	ASN479
B	ALA480
B	ALA481
B	ASP495
B	MG601
B	BEF602
B	K603

---

site_id	AC6
Number of Residues	3
Details	binding site for residue MG B 601

Chain	Residue
B	ASP87
B	ADP600
B	BEF602

---

site_id	AC7
Number of Residues	9
Details	binding site for residue BEF B 602

Chain	Residue
B	ASP52
B	GLY53
B	ASP87
B	THR89
B	THR90
B	ASP398
B	ADP600
B	MG601
B	K603

---

site_id	AC8
Number of Residues	5
Details	binding site for residue K B 603

Chain	Residue
B	THR30
B	LYS51
B	THR90
B	ADP600
B	BEF602

---

site_id	AC9
Number of Residues	22
Details	binding site for residue ADP C 600

Chain	Residue
C	K603
C	THR30
C	LEU31
C	GLY32
C	PRO33
C	LYS51
C	ASP87
C	GLY88
C	THR89
C	THR90
C	THR91
C	ILE150
C	GLY414
C	GLY415
C	ILE454
C	TYR478
C	ASN479
C	ALA480
C	ALA481
C	ASP495
C	MG601
C	BEF602

---

site_id	AD1
Number of Residues	3
Details	binding site for residue MG C 601

Chain	Residue
C	ASP87
C	ADP600
C	BEF602

---

site_id	AD2
Number of Residues	9
Details	binding site for residue BEF C 602

Chain	Residue
C	ASP52
C	GLY53
C	ASP87
C	THR89
C	THR90
C	ASP398
C	ADP600
C	MG601
C	K603

---

site_id	AD3
Number of Residues	5
Details	binding site for residue K C 603

Chain	Residue
C	THR30
C	LYS51
C	THR90
C	ADP600
C	BEF602

---

site_id	AD4
Number of Residues	22
Details	binding site for residue ADP D 600

Chain	Residue
D	THR30
D	LEU31
D	GLY32
D	PRO33
D	LYS51
D	ASP87
D	GLY88
D	THR89
D	THR90
D	THR91
D	ILE150
D	GLY414
D	GLY415
D	ILE454
D	TYR478
D	ASN479
D	ALA480
D	ALA481
D	ASP495
D	MG601
D	BEF602
D	K603

---

site_id	AD5
Number of Residues	3
Details	binding site for residue MG D 601

Chain	Residue
D	ASP87
D	ADP600
D	BEF602

---

site_id	AD6
Number of Residues	9
Details	binding site for residue BEF D 602

Chain	Residue
D	ASP52
D	GLY53
D	ASP87
D	THR89
D	THR90
D	ASP398
D	ADP600
D	MG601
D	K603

---

site_id	AD7
Number of Residues	5
Details	binding site for residue K D 603

Chain	Residue
D	THR30
D	LYS51
D	THR90
D	ADP600
D	BEF602

---

site_id	AD8
Number of Residues	22
Details	binding site for residue ADP E 600

Chain	Residue
E	THR30
E	LEU31
E	GLY32
E	PRO33
E	LYS51
E	ASP87
E	GLY88
E	THR89
E	THR90
E	THR91
E	ILE150
E	GLY414
E	GLY415
E	ILE454
E	TYR478
E	ASN479
E	ALA480
E	ALA481
E	ASP495
E	MG601
E	BEF602
E	K603

---

site_id	AD9
Number of Residues	3
Details	binding site for residue MG E 601

Chain	Residue
E	ASP87
E	ADP600
E	BEF602

---

site_id	AE1
Number of Residues	9
Details	binding site for residue BEF E 602

Chain	Residue
E	ASP52
E	GLY53
E	ASP87
E	THR89
E	THR90
E	ASP398
E	ADP600
E	MG601
E	K603

---

site_id	AE2
Number of Residues	5
Details	binding site for residue K E 603

Chain	Residue
E	THR30
E	LYS51
E	THR90
E	ADP600
E	BEF602

---

site_id	AE3
Number of Residues	22
Details	binding site for residue ADP F 600

Chain	Residue
F	THR30
F	LEU31
F	GLY32
F	PRO33
F	LYS51
F	ASP87
F	GLY88
F	THR89
F	THR90
F	THR91
F	ILE150
F	GLY414
F	GLY415
F	ILE454
F	TYR478
F	ASN479
F	ALA480
F	ALA481
F	ASP495
F	MG601
F	BEF602
F	K603

---

site_id	AE4
Number of Residues	3
Details	binding site for residue MG F 601

Chain	Residue
F	ASP87
F	ADP600
F	BEF602

---

site_id	AE5
Number of Residues	9
Details	binding site for residue BEF F 602

Chain	Residue
F	ASP52
F	GLY53
F	ASP87
F	THR89
F	THR90
F	ASP398
F	ADP600
F	MG601
F	K603

---

site_id	AE6
Number of Residues	5
Details	binding site for residue K F 603

Chain	Residue
F	THR30
F	LYS51
F	THR90
F	ADP600
F	BEF602

---

site_id	AE7
Number of Residues	22
Details	binding site for residue ADP G 600

Chain	Residue
G	THR30
G	LEU31
G	GLY32
G	PRO33
G	LYS51
G	ASP87
G	GLY88
G	THR89
G	THR90
G	THR91
G	ILE150
G	GLY414
G	GLY415
G	ILE454
G	TYR478
G	ASN479
G	ALA480
G	ALA481
G	ASP495
G	MG601
G	BEF602
G	K603

---

site_id	AE8
Number of Residues	4
Details	binding site for residue MG G 601

Chain	Residue
G	ASP87
G	SER151
G	ADP600
G	BEF602

---

site_id	AE9
Number of Residues	9
Details	binding site for residue BEF G 602

Chain	Residue
G	ASP52
G	GLY53
G	ASP87
G	THR89
G	THR90
G	ASP398
G	ADP600
G	MG601
G	K603

---

site_id	AF1
Number of Residues	5
Details	binding site for residue K G 603

Chain	Residue
G	THR30
G	LYS51
G	THR90
G	ADP600
G	BEF602

---

site_id	AF2
Number of Residues	22
Details	binding site for residue ADP H 600

Chain	Residue
H	THR30
H	LEU31
H	GLY32
H	PRO33
H	LYS51
H	ASP87
H	GLY88
H	THR89
H	THR90
H	THR91
H	ILE150
H	GLY414
H	GLY415
H	ILE454
H	TYR478
H	ASN479
H	ALA480
H	ALA481
H	ASP495
H	MG601
H	BEF602
H	K603

---

site_id	AF3
Number of Residues	3
Details	binding site for residue MG H 601

Chain	Residue
H	ASP87
H	ADP600
H	BEF602

---

site_id	AF4
Number of Residues	9
Details	binding site for residue BEF H 602

Chain	Residue
H	ASP52
H	GLY53
H	ASP87
H	THR89
H	THR90
H	ASP398
H	ADP600
H	MG601
H	K603

---

site_id	AF5
Number of Residues	5
Details	binding site for residue K H 603

Chain	Residue
H	THR30
H	LYS51
H	THR90
H	ADP600
H	BEF602

---

site_id	AF6
Number of Residues	22
Details	binding site for residue ADP I 600

Chain	Residue
I	THR30
I	LEU31
I	GLY32
I	PRO33
I	LYS51
I	ASP87
I	GLY88
I	THR89
I	THR90
I	THR91
I	ILE150
I	GLY414
I	GLY415
I	ILE454
I	TYR478
I	ASN479
I	ALA480
I	ALA481
I	ASP495
I	MG601
I	BEF602
I	K603

---

site_id	AF7
Number of Residues	3
Details	binding site for residue MG I 601

Chain	Residue
I	ASP87
I	ADP600
I	BEF602

---

site_id	AF8
Number of Residues	9
Details	binding site for residue BEF I 602

Chain	Residue
I	ASP52
I	GLY53
I	ASP87
I	THR89
I	THR90
I	ASP398
I	ADP600
I	MG601
I	K603

---

site_id	AF9
Number of Residues	5
Details	binding site for residue K I 603

Chain	Residue
I	THR30
I	LYS51
I	THR90
I	ADP600
I	BEF602

---

site_id	AG1
Number of Residues	22
Details	binding site for residue ADP J 600

Chain	Residue
J	THR30
J	LEU31
J	GLY32
J	PRO33
J	LYS51
J	ASP87
J	GLY88
J	THR89
J	THR90
J	THR91
J	ILE150
J	GLY414
J	GLY415
J	ILE454
J	TYR478
J	ASN479
J	ALA480
J	ALA481
J	ASP495
J	MG601
J	BEF602
J	K603

---

site_id	AG2
Number of Residues	3
Details	binding site for residue MG J 601

Chain	Residue
J	ASP87
J	ADP600
J	BEF602

---

site_id	AG3
Number of Residues	9
Details	binding site for residue BEF J 602

Chain	Residue
J	ASP52
J	GLY53
J	ASP87
J	THR89
J	THR90
J	ASP398
J	ADP600
J	MG601
J	K603

---

site_id	AG4
Number of Residues	5
Details	binding site for residue K J 603

Chain	Residue
J	THR30
J	LYS51
J	THR90
J	ADP600
J	BEF602

---

site_id	AG5
Number of Residues	22
Details	binding site for residue ADP K 600

Chain	Residue
K	THR30
K	LEU31
K	GLY32
K	PRO33
K	LYS51
K	ASP87
K	GLY88
K	THR89
K	THR90
K	THR91
K	ILE150
K	GLY414
K	GLY415
K	ILE454
K	TYR478
K	ASN479
K	ALA480
K	ALA481
K	ASP495
K	MG601
K	BEF602
K	K603

---

site_id	AG6
Number of Residues	3
Details	binding site for residue MG K 601

Chain	Residue
K	ASP87
K	ADP600
K	BEF602

---

site_id	AG7
Number of Residues	9
Details	binding site for residue BEF K 602

Chain	Residue
K	ASP52
K	GLY53
K	ASP87
K	THR89
K	THR90
K	ASP398
K	ADP600
K	MG601
K	K603

---

site_id	AG8
Number of Residues	5
Details	binding site for residue K K 603

Chain	Residue
K	THR30
K	LYS51
K	THR90
K	ADP600
K	BEF602

---

site_id	AG9
Number of Residues	22
Details	binding site for residue ADP L 600

Chain	Residue
L	THR30
L	LEU31
L	GLY32
L	PRO33
L	LYS51
L	ASP87
L	GLY88
L	THR89
L	THR90
L	THR91
L	ILE150
L	GLY414
L	GLY415
L	ILE454
L	TYR478
L	ASN479
L	ALA480
L	ALA481
L	ASP495
L	MG601
L	BEF602
L	K603

---

site_id	AH1
Number of Residues	3
Details	binding site for residue MG L 601

Chain	Residue
L	ASP87
L	ADP600
L	BEF602

---

site_id	AH2
Number of Residues	9
Details	binding site for residue BEF L 602

Chain	Residue
L	ASP52
L	GLY53
L	ASP87
L	THR89
L	THR90
L	ASP398
L	ADP600
L	MG601
L	K603

---

site_id	AH3
Number of Residues	5
Details	binding site for residue K L 603

Chain	Residue
L	THR30
L	LYS51
L	THR90
L	ADP600
L	BEF602

---

site_id	AH4
Number of Residues	22
Details	binding site for residue ADP M 600

Chain	Residue
M	THR30
M	LEU31
M	GLY32
M	PRO33
M	LYS51
M	ASP87
M	GLY88
M	THR89
M	THR90
M	THR91
M	ILE150
M	GLY414
M	GLY415
M	ILE454
M	TYR478
M	ASN479
M	ALA480
M	ALA481
M	ASP495
M	MG601
M	BEF602
M	K603

---

site_id	AH5
Number of Residues	3
Details	binding site for residue MG M 601

Chain	Residue
M	ASP87
M	ADP600
M	BEF602

---

site_id	AH6
Number of Residues	9
Details	binding site for residue BEF M 602

Chain	Residue
M	ASP52
M	GLY53
M	ASP87
M	THR89
M	THR90
M	ASP398
M	ADP600
M	MG601
M	K603

---

site_id	AH7
Number of Residues	5
Details	binding site for residue K M 603

Chain	Residue
M	THR30
M	LYS51
M	THR90
M	ADP600
M	BEF602

---

site_id	AH8
Number of Residues	22
Details	binding site for residue ADP N 600

Chain	Residue
N	THR30
N	LEU31
N	GLY32
N	PRO33
N	LYS51
N	ASP87
N	GLY88
N	THR89
N	THR90
N	THR91
N	ILE150
N	GLY414
N	GLY415
N	ILE454
N	TYR478
N	ASN479
N	ALA480
N	ALA481
N	ASP495
N	MG601
N	BEF602
N	K603

---

site_id	AH9
Number of Residues	3
Details	binding site for residue MG N 601

Chain	Residue
N	ASP87
N	ADP600
N	BEF602

---

site_id	AI1
Number of Residues	9
Details	binding site for residue BEF N 602

Chain	Residue
N	ASP52
N	GLY53
N	ASP87
N	THR89
N	THR90
N	ASP398
N	ADP600
N	MG601
N	K603

---

site_id	AI2
Number of Residues	5
Details	binding site for residue K N 603

Chain	Residue
N	THR30
N	LYS51
N	THR90
N	ADP600
N	BEF602

---

site_id	AI3
Number of Residues	24
Details	binding site for Di-peptide ASP Y 79 and ARG E 430

Chain	Residue
E	ARG58
E	LYS75
E	GLU76
E	VAL77
E	ALA78
E	LYS80
E	ALA81
E	ASN82
E	ASP83
E	LYS122
E	LYS122
E	ALA427
E	ASP428
E	LEU429
E	LEU429
E	GLY431
E	GLY431
E	ASN437
E	ILE440
Y	ASN2
Y	ILE78
Y	ASN80
Y	GLU81
Z	VAL95

---

Functional Information from PROSITE/UniProt

site_id	PS00296
Number of Residues	12
Details	CHAPERONINS_CPN60 Chaperonins cpn60 signature. AAVEEGVVaGGG

Chain	Residue	Details
A	ALA405-GLY416

---

site_id	PS00681
Number of Residues	25
Details	CHAPERONINS_CPN10 Chaperonins cpn10 signature. IrPLhDRVIVKrkevetksaGgIVL

Chain	Residue	Details
Y	ILE3-LEU27

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	14
Details	MOD_RES: N6-succinyllysine => ECO:0000269|PubMed:21151122

Chain	Residue	Details
1	LYS34
V	LYS34
W	LYS34
X	LYS34
Y	LYS34
Z	LYS34
C	ASP495
D	THR30
D	ASP87
D	GLY415
D	ASN479
2	LYS34
D	ASP495
E	THR30
E	ASP87
E	GLY415
E	ASN479
E	ASP495
F	THR30
F	ASP87
F	GLY415
F	ASN479
O	LYS34
F	ASP495
G	THR30
G	ASP87
G	GLY415
G	ASN479
G	ASP495
H	THR30
H	ASP87
H	GLY415
H	ASN479
P	LYS34
H	ASP495
I	THR30
I	ASP87
I	GLY415
I	ASN479
I	ASP495
J	THR30
J	ASP87
J	GLY415
J	ASN479
Q	LYS34
J	ASP495
K	THR30
K	ASP87
K	GLY415
K	ASN479
K	ASP495
L	THR30
L	ASP87
L	GLY415
L	ASN479
R	LYS34
L	ASP495
M	THR30
M	ASP87
M	GLY415
M	ASN479
M	ASP495
N	THR30
N	ASP87
N	GLY415
N	ASN479
S	LYS34
N	ASP495
T	LYS34
U	LYS34

---

site_id	SWS_FT_FI2
Number of Residues	14
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00600, ECO:0000269|PubMed:25174333, ECO:0000305|PubMed:14517228, ECO:0000305|PubMed:9285585, ECO:0007744|PDB:1AON, ECO:0007744|PDB:1PF9, ECO:0007744|PDB:3WVL

Chain	Residue	Details
A	LYS51
J	LYS51
K	LYS51
L	LYS51
M	LYS51
N	LYS51
B	LYS51
C	LYS51
D	LYS51
E	LYS51
F	LYS51
G	LYS51
H	LYS51
I	LYS51

---

site_id	SWS_FT_FI3
Number of Residues	70
Details	MOD_RES: N6-succinyllysine => ECO:0000269|PubMed:21151122

Chain	Residue	Details
A	LYS34
B	LYS390
C	LYS34
C	LYS51
C	LYS277
C	LYS321
C	LYS390
D	LYS34
D	LYS51
D	LYS277
D	LYS321
A	LYS51
D	LYS390
E	LYS34
E	LYS51
E	LYS277
E	LYS321
E	LYS390
F	LYS34
F	LYS51
F	LYS277
F	LYS321
A	LYS277
F	LYS390
G	LYS34
G	LYS51
G	LYS277
G	LYS321
G	LYS390
H	LYS34
H	LYS51
H	LYS277
H	LYS321
A	LYS321
H	LYS390
I	LYS34
I	LYS51
I	LYS277
I	LYS321
I	LYS390
J	LYS34
J	LYS51
J	LYS277
J	LYS321
A	LYS390
J	LYS390
K	LYS34
K	LYS51
K	LYS277
K	LYS321
K	LYS390
L	LYS34
L	LYS51
L	LYS277
L	LYS321
B	LYS34
L	LYS390
M	LYS34
M	LYS51
M	LYS277
M	LYS321
M	LYS390
N	LYS34
N	LYS51
N	LYS277
N	LYS321
B	LYS51
N	LYS390
B	LYS277
B	LYS321

---

site_id	SWS_FT_FI4
Number of Residues	14
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000269|PubMed:21151122

Chain	Residue	Details
A	LYS117
J	LYS117
K	LYS117
L	LYS117
M	LYS117
N	LYS117
B	LYS117
C	LYS117
D	LYS117
E	LYS117
F	LYS117
G	LYS117
H	LYS117
I	LYS117

---