5OMV

Ternary complex of 9N DNA polymerase in the replicative state with two metal ions in the active site

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003676	molecular_function	nucleic acid binding
A	0003677	molecular_function	DNA binding
A	0003887	molecular_function	DNA-directed DNA polymerase activity
A	0006260	biological_process	DNA replication
A	0006261	biological_process	DNA-templated DNA replication
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0034061	molecular_function	DNA polymerase activity
A	0071897	biological_process	DNA biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue MN A 801

Chain	Residue
A	ASP404
A	PHE405
A	ASP542
A	DTP806

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site_id	AC2
Number of Residues	6
Details	binding site for residue GOL A 802

Chain	Residue
P	DC12
A	TYR402
A	HIS545
A	TYR583
A	TYR594
A	ARG606

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site_id	AC3
Number of Residues	7
Details	binding site for residue MG A 803

Chain	Residue
A	TYR402
A	ASP404
A	ASP542
A	DTP806
A	HOH1001
A	HOH1031
P	DC12

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site_id	AC4
Number of Residues	2
Details	binding site for residue PGE A 804

Chain	Residue
A	TYR273
A	HOH1038

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site_id	AC5
Number of Residues	1
Details	binding site for residue PGE A 805

Chain	Residue
A	TYR110

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site_id	AC6
Number of Residues	19
Details	binding site for residue DTP A 806

Chain	Residue
A	ASP404
A	PHE405
A	SER407
A	LEU408
A	TYR409
A	ARG460
A	LYS487
A	ASN491
A	ASP542
A	MN801
A	MG803
A	HOH922
A	HOH935
A	HOH947
A	HOH975
A	HOH986
P	DC12
T	DT4
T	DG5

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site_id	AC7
Number of Residues	2
Details	binding site for residue MG T 101

Chain	Residue
A	ARG97
T	DC16

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Functional Information from PROSITE/UniProt

site_id	PS00116
Number of Residues	9
Details	DNA_POLYMERASE_B DNA polymerase family B signature. YADTDGLHA

Chain	Residue	Details
A	TYR538-ALA546

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