5OJJ
Crystal structure of the Zn-bound ubiquitin-conjugating enzyme Ube2T
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue ACT A 201 |
| Chain | Residue |
| A | ILE85 |
| A | CYS86 |
| A | LYS91 |
| A | ZN202 |
| A | HOH375 |
| C | PRO73 |
| C | HIS150 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 202 |
| Chain | Residue |
| A | ACT201 |
| C | HIS150 |
| A | CYS86 |
| A | LYS91 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue TRS A 203 |
| Chain | Residue |
| A | ASN119 |
| A | ASP122 |
| A | HOH377 |
| C | LYS149 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 204 |
| Chain | Residue |
| A | ASP127 |
| B | ASP127 |
| C | ASP127 |
| E | HIS12 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue ACT B 200 |
| Chain | Residue |
| A | HIS150 |
| B | ILE85 |
| B | CYS86 |
| B | LYS91 |
| B | ZN201 |
| B | HOH342 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 201 |
| Chain | Residue |
| A | HIS150 |
| B | CYS86 |
| B | LYS91 |
| B | ACT200 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue ACT C 200 |
| Chain | Residue |
| B | PRO73 |
| B | HIS150 |
| C | ILE85 |
| C | CYS86 |
| C | LYS91 |
| C | ZN201 |
| C | HOH361 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue ZN C 201 |
| Chain | Residue |
| B | HIS150 |
| C | CYS86 |
| C | LYS91 |
| C | ACT200 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue TRS C 202 |
| Chain | Residue |
| B | LYS149 |
| C | ASP88 |
| C | ASN119 |
| C | ASP122 |
| site_id | AD1 |
| Number of Residues | 7 |
| Details | binding site for residue ACT D 201 |
| Chain | Residue |
| D | ILE85 |
| D | CYS86 |
| D | LYS91 |
| D | ZN202 |
| D | HOH335 |
| E | PRO73 |
| E | HIS150 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN D 202 |
| Chain | Residue |
| D | CYS86 |
| D | LYS91 |
| D | ACT201 |
| E | HIS150 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN D 203 |
| Chain | Residue |
| C | HIS12 |
| D | ASP127 |
| E | ASP127 |
| F | ASP127 |
| site_id | AD4 |
| Number of Residues | 7 |
| Details | binding site for residue ACT E 200 |
| Chain | Residue |
| E | ILE85 |
| E | CYS86 |
| E | LYS91 |
| E | ZN201 |
| E | HOH310 |
| F | PRO73 |
| F | HIS150 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue ZN E 201 |
| Chain | Residue |
| E | CYS86 |
| E | LYS91 |
| E | ACT200 |
| F | HIS150 |
| site_id | AD6 |
| Number of Residues | 7 |
| Details | binding site for residue ACT F 200 |
| Chain | Residue |
| D | PRO73 |
| D | HIS150 |
| F | ILE85 |
| F | CYS86 |
| F | LYS91 |
| F | ZN201 |
| F | HOH307 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue ZN F 201 |
| Chain | Residue |
| D | HIS150 |
| F | CYS86 |
| F | LYS91 |
| F | ACT200 |
Functional Information from PROSITE/UniProt
| site_id | PS00183 |
| Number of Residues | 16 |
| Details | UBC_1 Ubiquitin-conjugating (UBC) active site signature. YHPNIdsa.GrICLdvL |
| Chain | Residue | Details |
| A | TYR75-LEU90 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Active site: {"description":"Glycyl thioester intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU00388","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"16916645","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19111657","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 150 |
| Details | Domain: {"description":"UBC core","evidences":[{"source":"PROSITE-ProRule","id":"PRU00388","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
