5OJ1

Penicillin Binding Protein 2x (PBP2x) from S.pneumoniae in complex with Oxacillin and a tetrasaccharide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005886	cellular_component	plasma membrane
A	0008360	biological_process	regulation of cell shape
A	0008658	molecular_function	penicillin binding
A	0009252	biological_process	peptidoglycan biosynthetic process
A	0016020	cellular_component	membrane
A	0046677	biological_process	response to antibiotic
A	0051301	biological_process	cell division
A	0071555	biological_process	cell wall organization

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	binding site for residue 1S6 A 801

Chain	Residue
A	SER337
A	GLY549
A	THR550
A	GLN552
A	LYS340
A	TRP374
A	ASN377
A	SER395
A	ASN397
A	PHE450
A	GLN452
A	SER548

---

site_id	AC2
Number of Residues	1
Details	binding site for residue NA A 802

Chain	Residue
A	SER548

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	59
Details	Domain: {"description":"PASTA 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00528","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	58
Details	Domain: {"description":"PASTA 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00528","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Active site: {"description":"Acyl-ester intermediate","evidences":[{"source":"UniProtKB","id":"P0AD65","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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