5OGE

Crystal structure of a nucleotide sugar transporter

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000139	cellular_component	Golgi membrane
A	0005458	molecular_function	GDP-mannose transmembrane transporter activity
A	0005739	cellular_component	mitochondrion
A	0005789	cellular_component	endoplasmic reticulum membrane
A	0005794	cellular_component	Golgi apparatus
A	0015297	molecular_function	antiporter activity
A	0030659	cellular_component	cytoplasmic vesicle membrane
A	0031410	cellular_component	cytoplasmic vesicle
A	0055085	biological_process	transmembrane transport
A	1990570	biological_process	GDP-mannose transmembrane transport
B	0000139	cellular_component	Golgi membrane
B	0005458	molecular_function	GDP-mannose transmembrane transporter activity
B	0005739	cellular_component	mitochondrion
B	0005789	cellular_component	endoplasmic reticulum membrane
B	0005794	cellular_component	Golgi apparatus
B	0015297	molecular_function	antiporter activity
B	0030659	cellular_component	cytoplasmic vesicle membrane
B	0031410	cellular_component	cytoplasmic vesicle
B	0055085	biological_process	transmembrane transport
B	1990570	biological_process	GDP-mannose transmembrane transport
C	0000139	cellular_component	Golgi membrane
C	0005458	molecular_function	GDP-mannose transmembrane transporter activity
C	0005739	cellular_component	mitochondrion
C	0005789	cellular_component	endoplasmic reticulum membrane
C	0005794	cellular_component	Golgi apparatus
C	0015297	molecular_function	antiporter activity
C	0030659	cellular_component	cytoplasmic vesicle membrane
C	0031410	cellular_component	cytoplasmic vesicle
C	0055085	biological_process	transmembrane transport
C	1990570	biological_process	GDP-mannose transmembrane transport
D	0000139	cellular_component	Golgi membrane
D	0005458	molecular_function	GDP-mannose transmembrane transporter activity
D	0005739	cellular_component	mitochondrion
D	0005789	cellular_component	endoplasmic reticulum membrane
D	0005794	cellular_component	Golgi apparatus
D	0015297	molecular_function	antiporter activity
D	0030659	cellular_component	cytoplasmic vesicle membrane
D	0031410	cellular_component	cytoplasmic vesicle
D	0055085	biological_process	transmembrane transport
D	1990570	biological_process	GDP-mannose transmembrane transport
E	0000139	cellular_component	Golgi membrane
E	0005458	molecular_function	GDP-mannose transmembrane transporter activity
E	0005739	cellular_component	mitochondrion
E	0005789	cellular_component	endoplasmic reticulum membrane
E	0005794	cellular_component	Golgi apparatus
E	0015297	molecular_function	antiporter activity
E	0030659	cellular_component	cytoplasmic vesicle membrane
E	0031410	cellular_component	cytoplasmic vesicle
E	0055085	biological_process	transmembrane transport
E	1990570	biological_process	GDP-mannose transmembrane transport
F	0000139	cellular_component	Golgi membrane
F	0005458	molecular_function	GDP-mannose transmembrane transporter activity
F	0005739	cellular_component	mitochondrion
F	0005789	cellular_component	endoplasmic reticulum membrane
F	0005794	cellular_component	Golgi apparatus
F	0015297	molecular_function	antiporter activity
F	0030659	cellular_component	cytoplasmic vesicle membrane
F	0031410	cellular_component	cytoplasmic vesicle
F	0055085	biological_process	transmembrane transport
F	1990570	biological_process	GDP-mannose transmembrane transport
G	0000139	cellular_component	Golgi membrane
G	0005458	molecular_function	GDP-mannose transmembrane transporter activity
G	0005739	cellular_component	mitochondrion
G	0005789	cellular_component	endoplasmic reticulum membrane
G	0005794	cellular_component	Golgi apparatus
G	0015297	molecular_function	antiporter activity
G	0030659	cellular_component	cytoplasmic vesicle membrane
G	0031410	cellular_component	cytoplasmic vesicle
G	0055085	biological_process	transmembrane transport
G	1990570	biological_process	GDP-mannose transmembrane transport
H	0000139	cellular_component	Golgi membrane
H	0005458	molecular_function	GDP-mannose transmembrane transporter activity
H	0005739	cellular_component	mitochondrion
H	0005789	cellular_component	endoplasmic reticulum membrane
H	0005794	cellular_component	Golgi apparatus
H	0015297	molecular_function	antiporter activity
H	0030659	cellular_component	cytoplasmic vesicle membrane
H	0031410	cellular_component	cytoplasmic vesicle
H	0055085	biological_process	transmembrane transport
H	1990570	biological_process	GDP-mannose transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	binding site for residue OLC A 401

Chain	Residue
A	CYS234

---

site_id	AC2
Number of Residues	4
Details	binding site for residue OLC A 402

Chain	Residue
A	TYR127
A	VAL137
E	MET140
E	LYS328

---

site_id	AC3
Number of Residues	2
Details	binding site for residue OLC A 403

Chain	Residue
A	PHE299
E	ARG304

---

site_id	AC4
Number of Residues	6
Details	binding site for residue OLC A 404

Chain	Residue
A	ILE292
A	SER295
A	GLY296
A	PHE300
A	ILE33
A	LYS40

---

site_id	AC5
Number of Residues	3
Details	binding site for residue OLC B 401

Chain	Residue
B	LEU310
B	LYS328
G	TYR127

---

site_id	AC6
Number of Residues	2
Details	binding site for residue OLC B 402

Chain	Residue
B	PHE93
B	TYR100

---

site_id	AC7
Number of Residues	5
Details	binding site for residue OLC D 401

Chain	Residue
D	MET140
D	LYS328
F	PHE117
F	ILE123
F	TYR127

---

site_id	AC8
Number of Residues	5
Details	binding site for residue OLC D 402

Chain	Residue
D	PHE186
D	TRP187
D	OLC403
D	OLC404
G	ARG336

---

site_id	AC9
Number of Residues	2
Details	binding site for residue OLC D 403

Chain	Residue
D	OLC402
D	OLC404

---

site_id	AD1
Number of Residues	3
Details	binding site for residue OLC D 404

Chain	Residue
D	LYS104
D	OLC402
D	OLC403

---

site_id	AD2
Number of Residues	4
Details	binding site for residue OLC D 405

Chain	Residue
D	PHE117
D	TYR127
D	VAL137
D	LEU142

---

site_id	AD3
Number of Residues	2
Details	binding site for residue OLC E 401

Chain	Residue
A	MET140
E	TYR127

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1480
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	288
Details	Topological domain: {"description":"Lumenal","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	168
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	96
Details	Binding site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	32
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---