Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5OBB

Structure of a modified mouse H chain ferritin with a lanthanide binding motif in complex with Terbium

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004322	molecular_function	ferroxidase activity
A	0005506	molecular_function	iron ion binding
A	0005576	cellular_component	extracellular region
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005764	cellular_component	lysosome
A	0005776	cellular_component	autophagosome
A	0005829	cellular_component	cytosol
A	0006826	biological_process	iron ion transport
A	0006879	biological_process	intracellular iron ion homeostasis
A	0006955	biological_process	immune response
A	0008198	molecular_function	ferrous iron binding
A	0008199	molecular_function	ferric iron binding
A	0008285	biological_process	negative regulation of cell population proliferation
A	0016020	cellular_component	membrane
A	0016491	molecular_function	oxidoreductase activity
A	0031410	cellular_component	cytoplasmic vesicle
A	0042802	molecular_function	identical protein binding
A	0044754	cellular_component	autolysosome
A	0046872	molecular_function	metal ion binding
A	0071682	cellular_component	endocytic vesicle lumen
A	0110076	biological_process	negative regulation of ferroptosis
B	0004322	molecular_function	ferroxidase activity
B	0005506	molecular_function	iron ion binding
B	0005576	cellular_component	extracellular region
B	0005737	cellular_component	cytoplasm
B	0005739	cellular_component	mitochondrion
B	0005764	cellular_component	lysosome
B	0005776	cellular_component	autophagosome
B	0005829	cellular_component	cytosol
B	0006826	biological_process	iron ion transport
B	0006879	biological_process	intracellular iron ion homeostasis
B	0006955	biological_process	immune response
B	0008198	molecular_function	ferrous iron binding
B	0008199	molecular_function	ferric iron binding
B	0008285	biological_process	negative regulation of cell population proliferation
B	0016020	cellular_component	membrane
B	0016491	molecular_function	oxidoreductase activity
B	0031410	cellular_component	cytoplasmic vesicle
B	0042802	molecular_function	identical protein binding
B	0044754	cellular_component	autolysosome
B	0046872	molecular_function	metal ion binding
B	0071682	cellular_component	endocytic vesicle lumen
B	0110076	biological_process	negative regulation of ferroptosis
C	0004322	molecular_function	ferroxidase activity
C	0005506	molecular_function	iron ion binding
C	0005576	cellular_component	extracellular region
C	0005737	cellular_component	cytoplasm
C	0005739	cellular_component	mitochondrion
C	0005764	cellular_component	lysosome
C	0005776	cellular_component	autophagosome
C	0005829	cellular_component	cytosol
C	0006826	biological_process	iron ion transport
C	0006879	biological_process	intracellular iron ion homeostasis
C	0006955	biological_process	immune response
C	0008198	molecular_function	ferrous iron binding
C	0008199	molecular_function	ferric iron binding
C	0008285	biological_process	negative regulation of cell population proliferation
C	0016020	cellular_component	membrane
C	0016491	molecular_function	oxidoreductase activity
C	0031410	cellular_component	cytoplasmic vesicle
C	0042802	molecular_function	identical protein binding
C	0044754	cellular_component	autolysosome
C	0046872	molecular_function	metal ion binding
C	0071682	cellular_component	endocytic vesicle lumen
C	0110076	biological_process	negative regulation of ferroptosis
D	0004322	molecular_function	ferroxidase activity
D	0005506	molecular_function	iron ion binding
D	0005576	cellular_component	extracellular region
D	0005737	cellular_component	cytoplasm
D	0005739	cellular_component	mitochondrion
D	0005764	cellular_component	lysosome
D	0005776	cellular_component	autophagosome
D	0005829	cellular_component	cytosol
D	0006826	biological_process	iron ion transport
D	0006879	biological_process	intracellular iron ion homeostasis
D	0006955	biological_process	immune response
D	0008198	molecular_function	ferrous iron binding
D	0008199	molecular_function	ferric iron binding
D	0008285	biological_process	negative regulation of cell population proliferation
D	0016020	cellular_component	membrane
D	0016491	molecular_function	oxidoreductase activity
D	0031410	cellular_component	cytoplasmic vesicle
D	0042802	molecular_function	identical protein binding
D	0044754	cellular_component	autolysosome
D	0046872	molecular_function	metal ion binding
D	0071682	cellular_component	endocytic vesicle lumen
D	0110076	biological_process	negative regulation of ferroptosis
E	0004322	molecular_function	ferroxidase activity
E	0005506	molecular_function	iron ion binding
E	0005576	cellular_component	extracellular region
E	0005737	cellular_component	cytoplasm
E	0005739	cellular_component	mitochondrion
E	0005764	cellular_component	lysosome
E	0005776	cellular_component	autophagosome
E	0005829	cellular_component	cytosol
E	0006826	biological_process	iron ion transport
E	0006879	biological_process	intracellular iron ion homeostasis
E	0006955	biological_process	immune response
E	0008198	molecular_function	ferrous iron binding
E	0008199	molecular_function	ferric iron binding
E	0008285	biological_process	negative regulation of cell population proliferation
E	0016020	cellular_component	membrane
E	0016491	molecular_function	oxidoreductase activity
E	0031410	cellular_component	cytoplasmic vesicle
E	0042802	molecular_function	identical protein binding
E	0044754	cellular_component	autolysosome
E	0046872	molecular_function	metal ion binding
E	0071682	cellular_component	endocytic vesicle lumen
E	0110076	biological_process	negative regulation of ferroptosis
F	0004322	molecular_function	ferroxidase activity
F	0005506	molecular_function	iron ion binding
F	0005576	cellular_component	extracellular region
F	0005737	cellular_component	cytoplasm
F	0005739	cellular_component	mitochondrion
F	0005764	cellular_component	lysosome
F	0005776	cellular_component	autophagosome
F	0005829	cellular_component	cytosol
F	0006826	biological_process	iron ion transport
F	0006879	biological_process	intracellular iron ion homeostasis
F	0006955	biological_process	immune response
F	0008198	molecular_function	ferrous iron binding
F	0008199	molecular_function	ferric iron binding
F	0008285	biological_process	negative regulation of cell population proliferation
F	0016020	cellular_component	membrane
F	0016491	molecular_function	oxidoreductase activity
F	0031410	cellular_component	cytoplasmic vesicle
F	0042802	molecular_function	identical protein binding
F	0044754	cellular_component	autolysosome
F	0046872	molecular_function	metal ion binding
F	0071682	cellular_component	endocytic vesicle lumen
F	0110076	biological_process	negative regulation of ferroptosis
G	0004322	molecular_function	ferroxidase activity
G	0005506	molecular_function	iron ion binding
G	0005576	cellular_component	extracellular region
G	0005737	cellular_component	cytoplasm
G	0005739	cellular_component	mitochondrion
G	0005764	cellular_component	lysosome
G	0005776	cellular_component	autophagosome
G	0005829	cellular_component	cytosol
G	0006826	biological_process	iron ion transport
G	0006879	biological_process	intracellular iron ion homeostasis
G	0006955	biological_process	immune response
G	0008198	molecular_function	ferrous iron binding
G	0008199	molecular_function	ferric iron binding
G	0008285	biological_process	negative regulation of cell population proliferation
G	0016020	cellular_component	membrane
G	0016491	molecular_function	oxidoreductase activity
G	0031410	cellular_component	cytoplasmic vesicle
G	0042802	molecular_function	identical protein binding
G	0044754	cellular_component	autolysosome
G	0046872	molecular_function	metal ion binding
G	0071682	cellular_component	endocytic vesicle lumen
G	0110076	biological_process	negative regulation of ferroptosis
H	0004322	molecular_function	ferroxidase activity
H	0005506	molecular_function	iron ion binding
H	0005576	cellular_component	extracellular region
H	0005737	cellular_component	cytoplasm
H	0005739	cellular_component	mitochondrion
H	0005764	cellular_component	lysosome
H	0005776	cellular_component	autophagosome
H	0005829	cellular_component	cytosol
H	0006826	biological_process	iron ion transport
H	0006879	biological_process	intracellular iron ion homeostasis
H	0006955	biological_process	immune response
H	0008198	molecular_function	ferrous iron binding
H	0008199	molecular_function	ferric iron binding
H	0008285	biological_process	negative regulation of cell population proliferation
H	0016020	cellular_component	membrane
H	0016491	molecular_function	oxidoreductase activity
H	0031410	cellular_component	cytoplasmic vesicle
H	0042802	molecular_function	identical protein binding
H	0044754	cellular_component	autolysosome
H	0046872	molecular_function	metal ion binding
H	0071682	cellular_component	endocytic vesicle lumen
H	0110076	biological_process	negative regulation of ferroptosis
I	0004322	molecular_function	ferroxidase activity
I	0005506	molecular_function	iron ion binding
I	0005576	cellular_component	extracellular region
I	0005737	cellular_component	cytoplasm
I	0005739	cellular_component	mitochondrion
I	0005764	cellular_component	lysosome
I	0005776	cellular_component	autophagosome
I	0005829	cellular_component	cytosol
I	0006826	biological_process	iron ion transport
I	0006879	biological_process	intracellular iron ion homeostasis
I	0006955	biological_process	immune response
I	0008198	molecular_function	ferrous iron binding
I	0008199	molecular_function	ferric iron binding
I	0008285	biological_process	negative regulation of cell population proliferation
I	0016020	cellular_component	membrane
I	0016491	molecular_function	oxidoreductase activity
I	0031410	cellular_component	cytoplasmic vesicle
I	0042802	molecular_function	identical protein binding
I	0044754	cellular_component	autolysosome
I	0046872	molecular_function	metal ion binding
I	0071682	cellular_component	endocytic vesicle lumen
I	0110076	biological_process	negative regulation of ferroptosis
J	0004322	molecular_function	ferroxidase activity
J	0005506	molecular_function	iron ion binding
J	0005576	cellular_component	extracellular region
J	0005737	cellular_component	cytoplasm
J	0005739	cellular_component	mitochondrion
J	0005764	cellular_component	lysosome
J	0005776	cellular_component	autophagosome
J	0005829	cellular_component	cytosol
J	0006826	biological_process	iron ion transport
J	0006879	biological_process	intracellular iron ion homeostasis
J	0006955	biological_process	immune response
J	0008198	molecular_function	ferrous iron binding
J	0008199	molecular_function	ferric iron binding
J	0008285	biological_process	negative regulation of cell population proliferation
J	0016020	cellular_component	membrane
J	0016491	molecular_function	oxidoreductase activity
J	0031410	cellular_component	cytoplasmic vesicle
J	0042802	molecular_function	identical protein binding
J	0044754	cellular_component	autolysosome
J	0046872	molecular_function	metal ion binding
J	0071682	cellular_component	endocytic vesicle lumen
J	0110076	biological_process	negative regulation of ferroptosis
K	0004322	molecular_function	ferroxidase activity
K	0005506	molecular_function	iron ion binding
K	0005576	cellular_component	extracellular region
K	0005737	cellular_component	cytoplasm
K	0005739	cellular_component	mitochondrion
K	0005764	cellular_component	lysosome
K	0005776	cellular_component	autophagosome
K	0005829	cellular_component	cytosol
K	0006826	biological_process	iron ion transport
K	0006879	biological_process	intracellular iron ion homeostasis
K	0006955	biological_process	immune response
K	0008198	molecular_function	ferrous iron binding
K	0008199	molecular_function	ferric iron binding
K	0008285	biological_process	negative regulation of cell population proliferation
K	0016020	cellular_component	membrane
K	0016491	molecular_function	oxidoreductase activity
K	0031410	cellular_component	cytoplasmic vesicle
K	0042802	molecular_function	identical protein binding
K	0044754	cellular_component	autolysosome
K	0046872	molecular_function	metal ion binding
K	0071682	cellular_component	endocytic vesicle lumen
K	0110076	biological_process	negative regulation of ferroptosis
L	0004322	molecular_function	ferroxidase activity
L	0005506	molecular_function	iron ion binding
L	0005576	cellular_component	extracellular region
L	0005737	cellular_component	cytoplasm
L	0005739	cellular_component	mitochondrion
L	0005764	cellular_component	lysosome
L	0005776	cellular_component	autophagosome
L	0005829	cellular_component	cytosol
L	0006826	biological_process	iron ion transport
L	0006879	biological_process	intracellular iron ion homeostasis
L	0006955	biological_process	immune response
L	0008198	molecular_function	ferrous iron binding
L	0008199	molecular_function	ferric iron binding
L	0008285	biological_process	negative regulation of cell population proliferation
L	0016020	cellular_component	membrane
L	0016491	molecular_function	oxidoreductase activity
L	0031410	cellular_component	cytoplasmic vesicle
L	0042802	molecular_function	identical protein binding
L	0044754	cellular_component	autolysosome
L	0046872	molecular_function	metal ion binding
L	0071682	cellular_component	endocytic vesicle lumen
L	0110076	biological_process	negative regulation of ferroptosis
M	0004322	molecular_function	ferroxidase activity
M	0005506	molecular_function	iron ion binding
M	0005576	cellular_component	extracellular region
M	0005737	cellular_component	cytoplasm
M	0005739	cellular_component	mitochondrion
M	0005764	cellular_component	lysosome
M	0005776	cellular_component	autophagosome
M	0005829	cellular_component	cytosol
M	0006826	biological_process	iron ion transport
M	0006879	biological_process	intracellular iron ion homeostasis
M	0006955	biological_process	immune response
M	0008198	molecular_function	ferrous iron binding
M	0008199	molecular_function	ferric iron binding
M	0008285	biological_process	negative regulation of cell population proliferation
M	0016020	cellular_component	membrane
M	0016491	molecular_function	oxidoreductase activity
M	0031410	cellular_component	cytoplasmic vesicle
M	0042802	molecular_function	identical protein binding
M	0044754	cellular_component	autolysosome
M	0046872	molecular_function	metal ion binding
M	0071682	cellular_component	endocytic vesicle lumen
M	0110076	biological_process	negative regulation of ferroptosis
N	0004322	molecular_function	ferroxidase activity
N	0005506	molecular_function	iron ion binding
N	0005576	cellular_component	extracellular region
N	0005737	cellular_component	cytoplasm
N	0005739	cellular_component	mitochondrion
N	0005764	cellular_component	lysosome
N	0005776	cellular_component	autophagosome
N	0005829	cellular_component	cytosol
N	0006826	biological_process	iron ion transport
N	0006879	biological_process	intracellular iron ion homeostasis
N	0006955	biological_process	immune response
N	0008198	molecular_function	ferrous iron binding
N	0008199	molecular_function	ferric iron binding
N	0008285	biological_process	negative regulation of cell population proliferation
N	0016020	cellular_component	membrane
N	0016491	molecular_function	oxidoreductase activity
N	0031410	cellular_component	cytoplasmic vesicle
N	0042802	molecular_function	identical protein binding
N	0044754	cellular_component	autolysosome
N	0046872	molecular_function	metal ion binding
N	0071682	cellular_component	endocytic vesicle lumen
N	0110076	biological_process	negative regulation of ferroptosis
O	0004322	molecular_function	ferroxidase activity
O	0005506	molecular_function	iron ion binding
O	0005576	cellular_component	extracellular region
O	0005737	cellular_component	cytoplasm
O	0005739	cellular_component	mitochondrion
O	0005764	cellular_component	lysosome
O	0005776	cellular_component	autophagosome
O	0005829	cellular_component	cytosol
O	0006826	biological_process	iron ion transport
O	0006879	biological_process	intracellular iron ion homeostasis
O	0006955	biological_process	immune response
O	0008198	molecular_function	ferrous iron binding
O	0008199	molecular_function	ferric iron binding
O	0008285	biological_process	negative regulation of cell population proliferation
O	0016020	cellular_component	membrane
O	0016491	molecular_function	oxidoreductase activity
O	0031410	cellular_component	cytoplasmic vesicle
O	0042802	molecular_function	identical protein binding
O	0044754	cellular_component	autolysosome
O	0046872	molecular_function	metal ion binding
O	0071682	cellular_component	endocytic vesicle lumen
O	0110076	biological_process	negative regulation of ferroptosis
P	0004322	molecular_function	ferroxidase activity
P	0005506	molecular_function	iron ion binding
P	0005576	cellular_component	extracellular region
P	0005737	cellular_component	cytoplasm
P	0005739	cellular_component	mitochondrion
P	0005764	cellular_component	lysosome
P	0005776	cellular_component	autophagosome
P	0005829	cellular_component	cytosol
P	0006826	biological_process	iron ion transport
P	0006879	biological_process	intracellular iron ion homeostasis
P	0006955	biological_process	immune response
P	0008198	molecular_function	ferrous iron binding
P	0008199	molecular_function	ferric iron binding
P	0008285	biological_process	negative regulation of cell population proliferation
P	0016020	cellular_component	membrane
P	0016491	molecular_function	oxidoreductase activity
P	0031410	cellular_component	cytoplasmic vesicle
P	0042802	molecular_function	identical protein binding
P	0044754	cellular_component	autolysosome
P	0046872	molecular_function	metal ion binding
P	0071682	cellular_component	endocytic vesicle lumen
P	0110076	biological_process	negative regulation of ferroptosis
Q	0004322	molecular_function	ferroxidase activity
Q	0005506	molecular_function	iron ion binding
Q	0005576	cellular_component	extracellular region
Q	0005737	cellular_component	cytoplasm
Q	0005739	cellular_component	mitochondrion
Q	0005764	cellular_component	lysosome
Q	0005776	cellular_component	autophagosome
Q	0005829	cellular_component	cytosol
Q	0006826	biological_process	iron ion transport
Q	0006879	biological_process	intracellular iron ion homeostasis
Q	0006955	biological_process	immune response
Q	0008198	molecular_function	ferrous iron binding
Q	0008199	molecular_function	ferric iron binding
Q	0008285	biological_process	negative regulation of cell population proliferation
Q	0016020	cellular_component	membrane
Q	0016491	molecular_function	oxidoreductase activity
Q	0031410	cellular_component	cytoplasmic vesicle
Q	0042802	molecular_function	identical protein binding
Q	0044754	cellular_component	autolysosome
Q	0046872	molecular_function	metal ion binding
Q	0071682	cellular_component	endocytic vesicle lumen
Q	0110076	biological_process	negative regulation of ferroptosis
R	0004322	molecular_function	ferroxidase activity
R	0005506	molecular_function	iron ion binding
R	0005576	cellular_component	extracellular region
R	0005737	cellular_component	cytoplasm
R	0005739	cellular_component	mitochondrion
R	0005764	cellular_component	lysosome
R	0005776	cellular_component	autophagosome
R	0005829	cellular_component	cytosol
R	0006826	biological_process	iron ion transport
R	0006879	biological_process	intracellular iron ion homeostasis
R	0006955	biological_process	immune response
R	0008198	molecular_function	ferrous iron binding
R	0008199	molecular_function	ferric iron binding
R	0008285	biological_process	negative regulation of cell population proliferation
R	0016020	cellular_component	membrane
R	0016491	molecular_function	oxidoreductase activity
R	0031410	cellular_component	cytoplasmic vesicle
R	0042802	molecular_function	identical protein binding
R	0044754	cellular_component	autolysosome
R	0046872	molecular_function	metal ion binding
R	0071682	cellular_component	endocytic vesicle lumen
R	0110076	biological_process	negative regulation of ferroptosis
S	0004322	molecular_function	ferroxidase activity
S	0005506	molecular_function	iron ion binding
S	0005576	cellular_component	extracellular region
S	0005737	cellular_component	cytoplasm
S	0005739	cellular_component	mitochondrion
S	0005764	cellular_component	lysosome
S	0005776	cellular_component	autophagosome
S	0005829	cellular_component	cytosol
S	0006826	biological_process	iron ion transport
S	0006879	biological_process	intracellular iron ion homeostasis
S	0006955	biological_process	immune response
S	0008198	molecular_function	ferrous iron binding
S	0008199	molecular_function	ferric iron binding
S	0008285	biological_process	negative regulation of cell population proliferation
S	0016020	cellular_component	membrane
S	0016491	molecular_function	oxidoreductase activity
S	0031410	cellular_component	cytoplasmic vesicle
S	0042802	molecular_function	identical protein binding
S	0044754	cellular_component	autolysosome
S	0046872	molecular_function	metal ion binding
S	0071682	cellular_component	endocytic vesicle lumen
S	0110076	biological_process	negative regulation of ferroptosis
T	0004322	molecular_function	ferroxidase activity
T	0005506	molecular_function	iron ion binding
T	0005576	cellular_component	extracellular region
T	0005737	cellular_component	cytoplasm
T	0005739	cellular_component	mitochondrion
T	0005764	cellular_component	lysosome
T	0005776	cellular_component	autophagosome
T	0005829	cellular_component	cytosol
T	0006826	biological_process	iron ion transport
T	0006879	biological_process	intracellular iron ion homeostasis
T	0006955	biological_process	immune response
T	0008198	molecular_function	ferrous iron binding
T	0008199	molecular_function	ferric iron binding
T	0008285	biological_process	negative regulation of cell population proliferation
T	0016020	cellular_component	membrane
T	0016491	molecular_function	oxidoreductase activity
T	0031410	cellular_component	cytoplasmic vesicle
T	0042802	molecular_function	identical protein binding
T	0044754	cellular_component	autolysosome
T	0046872	molecular_function	metal ion binding
T	0071682	cellular_component	endocytic vesicle lumen
T	0110076	biological_process	negative regulation of ferroptosis
U	0004322	molecular_function	ferroxidase activity
U	0005506	molecular_function	iron ion binding
U	0005576	cellular_component	extracellular region
U	0005737	cellular_component	cytoplasm
U	0005739	cellular_component	mitochondrion
U	0005764	cellular_component	lysosome
U	0005776	cellular_component	autophagosome
U	0005829	cellular_component	cytosol
U	0006826	biological_process	iron ion transport
U	0006879	biological_process	intracellular iron ion homeostasis
U	0006955	biological_process	immune response
U	0008198	molecular_function	ferrous iron binding
U	0008199	molecular_function	ferric iron binding
U	0008285	biological_process	negative regulation of cell population proliferation
U	0016020	cellular_component	membrane
U	0016491	molecular_function	oxidoreductase activity
U	0031410	cellular_component	cytoplasmic vesicle
U	0042802	molecular_function	identical protein binding
U	0044754	cellular_component	autolysosome
U	0046872	molecular_function	metal ion binding
U	0071682	cellular_component	endocytic vesicle lumen
U	0110076	biological_process	negative regulation of ferroptosis
V	0004322	molecular_function	ferroxidase activity
V	0005506	molecular_function	iron ion binding
V	0005576	cellular_component	extracellular region
V	0005737	cellular_component	cytoplasm
V	0005739	cellular_component	mitochondrion
V	0005764	cellular_component	lysosome
V	0005776	cellular_component	autophagosome
V	0005829	cellular_component	cytosol
V	0006826	biological_process	iron ion transport
V	0006879	biological_process	intracellular iron ion homeostasis
V	0006955	biological_process	immune response
V	0008198	molecular_function	ferrous iron binding
V	0008199	molecular_function	ferric iron binding
V	0008285	biological_process	negative regulation of cell population proliferation
V	0016020	cellular_component	membrane
V	0016491	molecular_function	oxidoreductase activity
V	0031410	cellular_component	cytoplasmic vesicle
V	0042802	molecular_function	identical protein binding
V	0044754	cellular_component	autolysosome
V	0046872	molecular_function	metal ion binding
V	0071682	cellular_component	endocytic vesicle lumen
V	0110076	biological_process	negative regulation of ferroptosis
W	0004322	molecular_function	ferroxidase activity
W	0005506	molecular_function	iron ion binding
W	0005576	cellular_component	extracellular region
W	0005737	cellular_component	cytoplasm
W	0005739	cellular_component	mitochondrion
W	0005764	cellular_component	lysosome
W	0005776	cellular_component	autophagosome
W	0005829	cellular_component	cytosol
W	0006826	biological_process	iron ion transport
W	0006879	biological_process	intracellular iron ion homeostasis
W	0006955	biological_process	immune response
W	0008198	molecular_function	ferrous iron binding
W	0008199	molecular_function	ferric iron binding
W	0008285	biological_process	negative regulation of cell population proliferation
W	0016020	cellular_component	membrane
W	0016491	molecular_function	oxidoreductase activity
W	0031410	cellular_component	cytoplasmic vesicle
W	0042802	molecular_function	identical protein binding
W	0044754	cellular_component	autolysosome
W	0046872	molecular_function	metal ion binding
W	0071682	cellular_component	endocytic vesicle lumen
W	0110076	biological_process	negative regulation of ferroptosis
X	0004322	molecular_function	ferroxidase activity
X	0005506	molecular_function	iron ion binding
X	0005576	cellular_component	extracellular region
X	0005737	cellular_component	cytoplasm
X	0005739	cellular_component	mitochondrion
X	0005764	cellular_component	lysosome
X	0005776	cellular_component	autophagosome
X	0005829	cellular_component	cytosol
X	0006826	biological_process	iron ion transport
X	0006879	biological_process	intracellular iron ion homeostasis
X	0006955	biological_process	immune response
X	0008198	molecular_function	ferrous iron binding
X	0008199	molecular_function	ferric iron binding
X	0008285	biological_process	negative regulation of cell population proliferation
X	0016020	cellular_component	membrane
X	0016491	molecular_function	oxidoreductase activity
X	0031410	cellular_component	cytoplasmic vesicle
X	0042802	molecular_function	identical protein binding
X	0044754	cellular_component	autolysosome
X	0046872	molecular_function	metal ion binding
X	0071682	cellular_component	endocytic vesicle lumen
X	0110076	biological_process	negative regulation of ferroptosis

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue TB A 201

Chain	Residue
A	GLU134
B	GLU134
C	GLU134

site_id	AC2
Number of Residues	4
Details	binding site for residue TB A 202

Chain	Residue
A	GLU27
A	GLU62
A	HIS65
A	GLN141

site_id	AC3
Number of Residues	5
Details	binding site for residue TB B 201

Chain	Residue
B	HIS65
B	VAL110
B	GLN141
B	GLU27
B	GLU62

site_id	AC4
Number of Residues	4
Details	binding site for residue TB C 201

Chain	Residue
C	GLU27
C	GLU62
C	HIS65
C	GLN141

site_id	AC5
Number of Residues	3
Details	binding site for residue TB D 201

Chain	Residue
D	GLU134
E	GLU134
F	GLU134

site_id	AC6
Number of Residues	4
Details	binding site for residue TB D 202

Chain	Residue
D	GLU27
D	GLU62
D	HIS65
D	GLN141

site_id	AC7
Number of Residues	4
Details	binding site for residue TB E 201

Chain	Residue
E	GLU27
E	GLU62
E	HIS65
E	GLN141

site_id	AC8
Number of Residues	4
Details	binding site for residue TB F 201

Chain	Residue
F	GLU27
F	GLU62
F	HIS65
F	GLN141

site_id	AC9
Number of Residues	3
Details	binding site for residue TB G 201

Chain	Residue
G	GLU134
H	GLU134
I	GLU134

site_id	AD1
Number of Residues	4
Details	binding site for residue TB G 202

Chain	Residue
G	GLU27
G	GLU62
G	HIS65
G	GLN141

site_id	AD2
Number of Residues	4
Details	binding site for residue TB H 201

Chain	Residue
H	GLU27
H	GLU62
H	HIS65
H	GLN141

site_id	AD3
Number of Residues	4
Details	binding site for residue TB I 201

Chain	Residue
I	GLU27
I	GLU62
I	HIS65
I	GLN141

site_id	AD4
Number of Residues	3
Details	binding site for residue TB J 201

Chain	Residue
J	GLU134
K	GLU134
L	GLU134

site_id	AD5
Number of Residues	4
Details	binding site for residue TB J 202

Chain	Residue
J	GLU27
J	GLU62
J	HIS65
J	GLN141

site_id	AD6
Number of Residues	4
Details	binding site for residue TB K 201

Chain	Residue
K	GLU27
K	GLU62
K	HIS65
K	GLN141

site_id	AD7
Number of Residues	4
Details	binding site for residue TB L 201

Chain	Residue
L	GLU27
L	GLU62
L	HIS65
L	GLN141

site_id	AD8
Number of Residues	3
Details	binding site for residue TB M 201

Chain	Residue
M	GLU134
N	GLU134
O	GLU134

site_id	AD9
Number of Residues	4
Details	binding site for residue TB M 202

Chain	Residue
M	GLU27
M	GLU62
M	HIS65
M	GLN141

site_id	AE1
Number of Residues	4
Details	binding site for residue TB N 201

Chain	Residue
N	GLU27
N	GLU62
N	HIS65
N	GLN141

site_id	AE2
Number of Residues	4
Details	binding site for residue TB O 201

Chain	Residue
O	GLU27
O	GLU62
O	HIS65
O	GLN141

site_id	AE3
Number of Residues	3
Details	binding site for residue TB P 201

Chain	Residue
P	GLU134
Q	GLU134
R	GLU134

site_id	AE4
Number of Residues	4
Details	binding site for residue TB P 202

Chain	Residue
P	GLU27
P	GLU62
P	HIS65
P	GLN141

site_id	AE5
Number of Residues	4
Details	binding site for residue TB Q 201

Chain	Residue
Q	GLU27
Q	GLU62
Q	HIS65
Q	GLN141

site_id	AE6
Number of Residues	4
Details	binding site for residue TB R 201

Chain	Residue
R	GLU27
R	GLU62
R	HIS65
R	GLN141

site_id	AE7
Number of Residues	4
Details	binding site for residue TB S 201

Chain	Residue
S	GLU27
S	GLU62
S	HIS65
S	GLN141

site_id	AE8
Number of Residues	4
Details	binding site for residue TB T 201

Chain	Residue
T	GLU27
T	GLU62
T	HIS65
T	GLN141

site_id	AE9
Number of Residues	3
Details	binding site for residue TB S 202

Chain	Residue
S	GLU134
T	GLU134
U	GLU134

site_id	AF1
Number of Residues	4
Details	binding site for residue TB U 201

Chain	Residue
U	GLU27
U	GLU62
U	HIS65
U	GLN141

site_id	AF2
Number of Residues	3
Details	binding site for residue TB V 201

Chain	Residue
V	GLU134
W	GLU134
X	GLU134

site_id	AF3
Number of Residues	4
Details	binding site for residue TB V 202

Chain	Residue
V	GLU27
V	GLU62
V	HIS65
V	GLN141

site_id	AF4
Number of Residues	4
Details	binding site for residue TB W 201

Chain	Residue
W	GLU27
W	GLU62
W	HIS65
W	GLN141

site_id	AF5
Number of Residues	4
Details	binding site for residue TB X 201

Chain	Residue
X	GLU27
X	GLU62
X	HIS65
X	GLN141

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DTNNDGWIEgdEL

Chain	Residue	Details
A	ASP182-LEU194

site_id	PS00204
Number of Residues	21
Details	FERRITIN_2 Ferritin iron-binding regions signature 2. DphLCDFIEtyYLseqvksIK

Chain	Residue	Details
A	ASP126-LYS146

site_id	PS00540
Number of Residues	19
Details	FERRITIN_1 Ferritin iron-binding regions signature 1. EeREhaEKLMklQNqRgGR

Chain	Residue	Details
A	GLU61-ARG79

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3576
Details	Domain: {"description":"Ferritin-like diiron","evidences":[{"source":"PROSITE-ProRule","id":"PRU00085","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	120
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00085","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)