Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004503 | molecular_function | tyrosinase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0042438 | biological_process | melanin biosynthetic process |
| A | 0043473 | biological_process | pigmentation |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004503 | molecular_function | tyrosinase activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0042438 | biological_process | melanin biosynthetic process |
| B | 0043473 | biological_process | pigmentation |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue CU A 301 |
| Chain | Residue |
| A | HIS204 |
| A | HIS208 |
| A | HIS231 |
| A | SVF303 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue CU A 302 |
| Chain | Residue |
| A | HIS42 |
| A | HIS60 |
| A | HIS69 |
| A | PHE227 |
| A | SVF303 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | binding site for residue SVF A 303 |
| Chain | Residue |
| A | HIS42 |
| A | HIS60 |
| A | HIS69 |
| A | PRO201 |
| A | HIS204 |
| A | ASN205 |
| A | HIS208 |
| A | ARG209 |
| A | VAL218 |
| A | CU301 |
| A | CU302 |
| B | LYS254 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue CU B 301 |
| Chain | Residue |
| B | HIS42 |
| B | HIS60 |
| B | HIS69 |
| B | PHE227 |
| B | SVF303 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue CU B 302 |
| Chain | Residue |
| B | HIS204 |
| B | HIS208 |
| B | PHE227 |
| B | HIS231 |
| B | SVF303 |
| site_id | AC6 |
| Number of Residues | 11 |
| Details | binding site for residue SVF B 303 |
| Chain | Residue |
| B | HIS42 |
| B | HIS60 |
| B | HIS69 |
| B | SER82 |
| B | PRO201 |
| B | HIS204 |
| B | ASN205 |
| B | ARG209 |
| B | VAL218 |
| B | CU301 |
| B | CU302 |
Functional Information from PROSITE/UniProt
| site_id | PS00497 |
| Number of Residues | 18 |
| Details | TYROSINASE_1 Tyrosinase CuA-binding region signature. Hmssa.FLpWHReyLlrfE |
| Chain | Residue | Details |
| A | HIS60-GLU77 | |
| site_id | PS00498 |
| Number of Residues | 12 |
| Details | TYROSINASE_2 Tyrosinase and hemocyanins CuB-binding region signature. DPvFFlhHanvD |
| Chain | Residue | Details |
| A | ASP224-ASP235 | |
