Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0004518 | molecular_function | nuclease activity |
| A | 0004519 | molecular_function | endonuclease activity |
| A | 0004540 | molecular_function | RNA nuclease activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0005764 | cellular_component | lysosome |
| A | 0006401 | biological_process | RNA catabolic process |
| A | 0006952 | biological_process | defense response |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0019731 | biological_process | antibacterial humoral response |
| A | 0031410 | cellular_component | cytoplasmic vesicle |
| A | 0042742 | biological_process | defense response to bacterium |
| A | 0045087 | biological_process | innate immune response |
| A | 0050829 | biological_process | defense response to Gram-negative bacterium |
| A | 0050830 | biological_process | defense response to Gram-positive bacterium |
| A | 0051607 | biological_process | defense response to virus |
| A | 0061844 | biological_process | antimicrobial humoral immune response mediated by antimicrobial peptide |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue PO4 A 201 |
| Chain | Residue |
| A | LYS3 |
| A | HOH475 |
| A | ARG4 |
| A | LYS100 |
| A | HOH312 |
| A | HOH329 |
| A | HOH334 |
| A | HOH341 |
| A | HOH359 |
| A | HOH468 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue PO4 A 202 |
| Chain | Residue |
| A | HIS15 |
| A | HIS122 |
| A | LEU123 |
| A | CL211 |
| A | HOH311 |
| A | HOH345 |
| A | HOH348 |
| A | HOH349 |
| A | HOH434 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue PO4 A 203 |
| Chain | Residue |
| A | HIS36 |
| A | HIS39 |
| A | LYS87 |
| A | HOH303 |
| A | HOH305 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 A 204 |
| Chain | Residue |
| A | ARG92 |
| A | HOH315 |
| A | HOH399 |
| A | HOH406 |
| site_id | AC5 |
| Number of Residues | 11 |
| Details | binding site for residue PO4 A 205 |
| Chain | Residue |
| A | ARG66 |
| A | HIS67 |
| A | HIS67 |
| A | ASN68 |
| A | HOH301 |
| A | HOH307 |
| A | HOH314 |
| A | HOH314 |
| A | HOH318 |
| A | HOH326 |
| A | HOH470 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue PO4 A 206 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue NA A 207 |
| Chain | Residue |
| A | TRP1 |
| A | LYS7 |
| A | PRO18 |
| A | HIS45 |
| A | CL210 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue NA A 208 |
| Chain | Residue |
| A | MET0 |
| A | TRP1 |
| A | TYR99 |
| A | HOH474 |
| A | HOH586 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue NA A 209 |
| Chain | Residue |
| A | LYS7 |
| A | VAL121 |
| A | CL211 |
| A | HOH349 |
| A | HOH521 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 210 |
| Chain | Residue |
| A | HIS122 |
| A | NA207 |
| A | HOH309 |
| A | HOH500 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue CL A 211 |
| Chain | Residue |
| A | PHE11 |
| A | GLN14 |
| A | HIS15 |
| A | PO4202 |
| A | NA209 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue CL A 212 |
| Chain | Residue |
| A | LYS7 |
| A | PRO20 |
| A | GLN110 |
| A | K213 |
| A | HOH346 |
| A | HOH553 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue K A 213 |
| Chain | Residue |
| A | PRO20 |
| A | GLN110 |
| A | CL212 |
| A | HOH316 |
| A | HOH456 |
Functional Information from PROSITE/UniProt
| site_id | PS00127 |
| Number of Residues | 7 |
| Details | RNASE_PANCREATIC Pancreatic ribonuclease family signature. CKhqNTF |
| Chain | Residue | Details |
| A | CYS37-PHE43 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"UniProtKB","id":"Q64438","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"UniProtKB","id":"Q64438","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Site: {"description":"Important for bactericidal activity, bacterial agglutination activity and binding to bacterial lipopolysaccharide (LPS)","evidences":[{"source":"PubMed","id":"27089320","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Site: {"description":"Facilitates cleavage of polynucleotide substrates","evidences":[{"source":"PubMed","id":"27013146","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Site: {"description":"Critical for catalytic activity","evidences":[{"source":"UniProtKB","id":"Q9H1E1","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
