5O8Y

Conformational dynamism for DNA interaction in Salmonella typhimurium RcsB response regulator.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000160	biological_process	phosphorelay signal transduction system
A	0003677	molecular_function	DNA binding
A	0006355	biological_process	regulation of DNA-templated transcription
C	0000160	biological_process	phosphorelay signal transduction system
C	0003677	molecular_function	DNA binding
C	0006355	biological_process	regulation of DNA-templated transcription
D	0000160	biological_process	phosphorelay signal transduction system
D	0003677	molecular_function	DNA binding
D	0006355	biological_process	regulation of DNA-templated transcription
F	0000160	biological_process	phosphorelay signal transduction system
F	0003677	molecular_function	DNA binding
F	0006355	biological_process	regulation of DNA-templated transcription
G	0000160	biological_process	phosphorelay signal transduction system
G	0003677	molecular_function	DNA binding
G	0006355	biological_process	regulation of DNA-templated transcription
H	0000160	biological_process	phosphorelay signal transduction system
H	0003677	molecular_function	DNA binding
H	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	binding site for residue PE4 A 301

Chain	Residue
A	ILE42
A	ASN43
A	TYR64
A	TYR73
A	PHE78
D	TYR73
D	HIS77
G	TYR64
G	TYR73

---

site_id	AC2
Number of Residues	8
Details	binding site for residue SO4 A 302

Chain	Residue
A	ASP56
A	LEU57
A	SER58
A	THR87
A	MET88
A	LYS109
A	HOH408
C	HOH406

---

site_id	AC3
Number of Residues	2
Details	binding site for residue SO4 A 303

Chain	Residue
A	ARG20
F	LYS21

---

site_id	AC4
Number of Residues	5
Details	binding site for residue SO4 A 304

Chain	Residue
A	ARG76
D	ARG76
D	HIS77
G	ARG76
G	HIS77

---

site_id	AC5
Number of Residues	7
Details	binding site for residue PE4 C 301

Chain	Residue
C	PRO46
C	TYR64
C	TYR73
F	TYR64
F	TYR73
H	ILE42
H	TYR73

---

site_id	AC6
Number of Residues	11
Details	binding site for residue SO4 C 302

Chain	Residue
A	GLU170
A	HOH401
C	HIS12
C	ASP56
C	LEU57
C	SER58
C	LEU86
C	THR87
C	MET88
C	ASN89
C	LYS109

---

site_id	AC7
Number of Residues	4
Details	binding site for residue SO4 C 303

Chain	Residue
C	THR39
C	GLY61
C	ASP62
C	LYS63

---

site_id	AC8
Number of Residues	9
Details	binding site for residue SO4 D 301

Chain	Residue
D	HIS12
D	ASP56
D	LEU57
D	SER58
D	LEU86
D	THR87
D	MET88
D	LYS109
F	GLU170

---

site_id	AC9
Number of Residues	8
Details	binding site for residue SO4 G 301

Chain	Residue
G	HIS12
G	ASP56
G	LEU57
G	SER58
G	THR87
G	MET88
G	LYS109
G	HOH404

---

site_id	AD1
Number of Residues	7
Details	binding site for residue SO4 F 301

Chain	Residue
D	HOH402
F	ASP56
F	LEU57
F	SER58
F	THR87
F	MET88
F	LYS109

---

site_id	AD2
Number of Residues	2
Details	binding site for residue SO4 F 302

Chain	Residue
F	ARG20
F	LYS21

---

site_id	AD3
Number of Residues	8
Details	binding site for residue SO4 H 301

Chain	Residue
G	HOH416
H	ASP56
H	LEU57
H	SER58
H	THR87
H	MET88
H	ASN89
H	LYS109

---

Functional Information from PROSITE/UniProt

site_id	PS00622
Number of Residues	28
Details	HTH_LUXR_1 LuxR-type HTH domain signature. GflVteIAkkLnRsikTIssQkkSAmmK

Chain	Residue	Details
A	GLY165-LYS192

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	114
Details	DNA_BIND: H-T-H motif => ECO:0000255|HAMAP-Rule:MF_00981

Chain	Residue	Details
A	VAL168-LYS187
C	VAL168-LYS187
D	VAL168-LYS187
G	VAL168-LYS187
F	VAL168-LYS187
H	VAL168-LYS187

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	MOD_RES: 4-aspartylphosphate => ECO:0000255|HAMAP-Rule:MF_00981

Chain	Residue	Details
A	ASP56
C	ASP56
D	ASP56
G	ASP56
F	ASP56
H	ASP56

---