Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5O85

p34-p44 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000438	cellular_component	core TFIIH complex portion of holo TFIIH complex
A	0000439	cellular_component	transcription factor TFIIH core complex
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005669	cellular_component	transcription factor TFIID complex
A	0005675	cellular_component	transcription factor TFIIH holo complex
A	0006281	biological_process	DNA repair
A	0006289	biological_process	nucleotide-excision repair
A	0006355	biological_process	regulation of DNA-templated transcription
A	0006366	biological_process	transcription by RNA polymerase II
A	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
A	0046872	molecular_function	metal ion binding
A	0097550	cellular_component	transcription preinitiation complex
B	0000438	cellular_component	core TFIIH complex portion of holo TFIIH complex
B	0000439	cellular_component	transcription factor TFIIH core complex
B	0002031	biological_process	G protein-coupled receptor internalization
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005669	cellular_component	transcription factor TFIID complex
B	0005675	cellular_component	transcription factor TFIIH holo complex
B	0006281	biological_process	DNA repair
B	0006289	biological_process	nucleotide-excision repair
B	0006351	biological_process	DNA-templated transcription
B	0006357	biological_process	regulation of transcription by RNA polymerase II
B	0006366	biological_process	transcription by RNA polymerase II
B	0006367	biological_process	transcription initiation at RNA polymerase II promoter
B	0008270	molecular_function	zinc ion binding
B	0009411	biological_process	response to UV
B	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
B	0016607	cellular_component	nuclear speck
B	0046872	molecular_function	metal ion binding
C	0000438	cellular_component	core TFIIH complex portion of holo TFIIH complex
C	0000439	cellular_component	transcription factor TFIIH core complex
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005669	cellular_component	transcription factor TFIID complex
C	0005675	cellular_component	transcription factor TFIIH holo complex
C	0006281	biological_process	DNA repair
C	0006289	biological_process	nucleotide-excision repair
C	0006355	biological_process	regulation of DNA-templated transcription
C	0006366	biological_process	transcription by RNA polymerase II
C	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
C	0046872	molecular_function	metal ion binding
C	0097550	cellular_component	transcription preinitiation complex
D	0000438	cellular_component	core TFIIH complex portion of holo TFIIH complex
D	0000439	cellular_component	transcription factor TFIIH core complex
D	0002031	biological_process	G protein-coupled receptor internalization
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005669	cellular_component	transcription factor TFIID complex
D	0005675	cellular_component	transcription factor TFIIH holo complex
D	0006281	biological_process	DNA repair
D	0006289	biological_process	nucleotide-excision repair
D	0006351	biological_process	DNA-templated transcription
D	0006357	biological_process	regulation of transcription by RNA polymerase II
D	0006366	biological_process	transcription by RNA polymerase II
D	0006367	biological_process	transcription initiation at RNA polymerase II promoter
D	0008270	molecular_function	zinc ion binding
D	0009411	biological_process	response to UV
D	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
D	0016607	cellular_component	nuclear speck
D	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN B 401

Chain	Residue
B	CYS345
B	CYS348
B	CYS368
B	CYS371

site_id	AC2
Number of Residues	4
Details	binding site for residue ZN B 402

Chain	Residue
B	CYS360
B	CYS363
B	CYS382
B	CYS385

site_id	AC3
Number of Residues	4
Details	binding site for residue ZN D 401

Chain	Residue
D	CYS348
D	CYS368
D	CYS371
D	CYS345

site_id	AC4
Number of Residues	4
Details	binding site for residue ZN D 402

Chain	Residue
D	CYS360
D	CYS363
D	CYS382
D	CYS385

site_id	AC5
Number of Residues	7
Details	binding site for Di-peptide GLU C 150 and VAL C 151

Chain	Residue
C	ARG146
C	ASN148
C	LYS149
C	LYS149
C	LYS152
C	LYS152
C	GLN155

Functional Information from PROSITE/UniProt

site_id	PS00028
Number of Residues	21
Details	ZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. Cav..CqnvFcvdcdvfvHdsl..H

Chain	Residue	Details
B	CYS360-HIS380

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	34
Details	ZN_FING: C4-type

Chain	Residue	Details
B	CYS291-CYS308
D	CYS291-CYS308

site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: Phosphotyrosine => ECO:0000250\|UniProtKB:A0JN27

Chain	Residue	Details
B	TYR95
D	TYR95

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)