5O5F
Crystal structure of the human BRPF1 bromodomain in complex with BZ038
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue 9LT A 801 |
| Chain | Residue |
| A | ILE652 |
| A | NO3803 |
| A | HOH930 |
| A | HOH932 |
| A | HOH994 |
| A | PHE653 |
| A | PRO658 |
| A | GLU661 |
| A | TYR707 |
| A | ASN708 |
| A | PHE714 |
| A | ARG734 |
| A | LYS738 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue NO3 A 802 |
| Chain | Residue |
| A | SER702 |
| A | LEU705 |
| A | LYS706 |
| A | TYR715 |
| A | ARG722 |
| A | HOH1004 |
| A | HOH1026 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue NO3 A 803 |
| Chain | Residue |
| A | GLU627 |
| A | PHE714 |
| A | ARG734 |
| A | 9LT801 |
| A | HOH917 |
Functional Information from PROSITE/UniProt
| site_id | PS00633 |
| Number of Residues | 58 |
| Details | BROMODOMAIN_1 Bromodomain signature. GniFsepvPlsevp..DYLdhIkkpMdfftMkqnleayr..Ylnfddfeedfnl.IvsNClkY |
| Chain | Residue | Details |
| A | GLY650-TYR707 |
