Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003723 | molecular_function | RNA binding |
A | 0005634 | cellular_component | nucleus |
A | 0005737 | cellular_component | cytoplasm |
A | 0016567 | biological_process | protein ubiquitination |
A | 0019941 | biological_process | modification-dependent protein catabolic process |
A | 0031386 | molecular_function | protein tag activity |
A | 0031625 | molecular_function | ubiquitin protein ligase binding |
A | 0046872 | molecular_function | metal ion binding |
E | 0003723 | molecular_function | RNA binding |
E | 0005634 | cellular_component | nucleus |
E | 0005737 | cellular_component | cytoplasm |
E | 0016567 | biological_process | protein ubiquitination |
E | 0019941 | biological_process | modification-dependent protein catabolic process |
E | 0031386 | molecular_function | protein tag activity |
E | 0031625 | molecular_function | ubiquitin protein ligase binding |
E | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 3 |
Details | binding site for residue SO4 A 101 |
Chain | Residue |
A | ARG42 |
A | ARG72 |
A | ARG74 |
site_id | AC2 |
Number of Residues | 5 |
Details | binding site for residue SO4 A 102 |
Chain | Residue |
A | ARG72 |
E | ARG42 |
E | GLN49 |
E | ARG72 |
E | HOH206 |
site_id | AC3 |
Number of Residues | 2 |
Details | binding site for residue MG A 103 |
site_id | AC4 |
Number of Residues | 3 |
Details | binding site for residue SO4 C 101 |
Chain | Residue |
C | ARG42 |
C | GLN49 |
D | ARG42 |
site_id | AC5 |
Number of Residues | 2 |
Details | binding site for residue SO4 C 102 |
site_id | AC6 |
Number of Residues | 3 |
Details | binding site for residue MG D 101 |
Chain | Residue |
D | THR55 |
D | SER57 |
D | ASP58 |
site_id | AC7 |
Number of Residues | 4 |
Details | binding site for residue SO4 B 101 |
Chain | Residue |
A | GLN62 |
B | ARG54 |
B | ASP58 |
D | GLY10 |
site_id | AC8 |
Number of Residues | 6 |
Details | binding site for residue SO4 B 102 |
Chain | Residue |
B | ARG42 |
B | GLN49 |
B | ARG72 |
F | ARG42 |
F | GLN49 |
F | ARG72 |
site_id | AC9 |
Number of Residues | 7 |
Details | binding site for residue SO4 E 101 |
Chain | Residue |
E | ILE44 |
E | ALA46 |
E | GLY47 |
E | HIS68 |
F | PHE45 |
F | SER65 |
F | THR66 |
site_id | AD1 |
Number of Residues | 6 |
Details | binding site for residue SO4 E 102 |
Chain | Residue |
A | ILE44 |
A | GLY47 |
A | HIS68 |
D | SER65 |
E | ARG72 |
E | ARG74 |
site_id | AD2 |
Number of Residues | 5 |
Details | binding site for residue SO4 E 103 |
Chain | Residue |
A | LEU73 |
A | ARG74 |
E | THR9 |
E | GLU34 |
E | HOH201 |
site_id | AD3 |
Number of Residues | 4 |
Details | binding site for residue MG E 104 |
Chain | Residue |
D | SER57 |
E | GLU24 |
E | ASP39 |
E | ASP52 |
site_id | AD4 |
Number of Residues | 19 |
Details | binding site for Di-peptide LYS B 48 and GLY F 76 |
Chain | Residue |
B | ILE44 |
B | PHE45 |
B | ALA46 |
B | GLY47 |
B | GLN49 |
B | LEU50 |
B | TYR59 |
C | ALA46 |
D | LEU71 |
F | ILE44 |
F | PHE45 |
F | ALA46 |
F | GLY47 |
F | GLN49 |
F | LEU50 |
F | LEU71 |
F | LEU73 |
F | ARG74 |
F | GLY75 |
Functional Information from PROSITE/UniProt
site_id | PS00299 |
Number of Residues | 26 |
Details | UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGcqleD |
Chain | Residue | Details |
A | LYS27-ASP52 | |
C | LYS27-ASP52 | |
D | LYS27-ASP52 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 4 |
Details | SITE: Interacts with activating enzyme |
Chain | Residue | Details |
D | ARG54 | |
D | ARG72 | |
F | ARG54 | |
F | ARG72 | |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | SITE: Essential for function |
Chain | Residue | Details |
D | HIS68 | |
F | HIS68 | |
Chain | Residue | Details |
D | SER65 | |
F | SER65 | |
Chain | Residue | Details |
D | THR66 | |
F | THR66 | |
Chain | Residue | Details |
D | GLY76 | |
F | GLY76 | |
site_id | SWS_FT_FI6 |
Number of Residues | 2 |
Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16443603 |
Chain | Residue | Details |
D | LYS6 | |
F | LYS6 | |
B | LYS63 | |
site_id | SWS_FT_FI7 |
Number of Residues | 4 |
Details | CROSSLNK: Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins) |
Chain | Residue | Details |
C | LYS11 | |
D | GLY76 | |
B | LYS11 | |
F | GLY76 | |
Chain | Residue | Details |
D | LYS11 | |
D | ARG48 | |
F | LYS11 | |
F | ARG48 | |
site_id | SWS_FT_FI9 |
Number of Residues | 2 |
Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000305|PubMed:15466860 |
Chain | Residue | Details |
D | LYS27 | |
F | LYS27 | |
Chain | Residue | Details |
D | LYS29 | |
F | LYS29 | |
site_id | SWS_FT_FI11 |
Number of Residues | 2 |
Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:25752577 |
Chain | Residue | Details |
D | LYS33 | |
F | LYS33 | |
Chain | Residue | Details |
D | LYS63 | |
F | LYS63 | |