5O3E
Human Brd2(BD2) mutant in complex with Me-Am1
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue 9HW A 501 |
| Chain | Residue |
| A | TRP370 |
| A | HOH630 |
| A | PRO371 |
| A | PHE372 |
| A | VAL383 |
| A | ASN429 |
| A | ASP434 |
| A | VAL435 |
| A | MET438 |
| A | HOH612 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 502 |
| Chain | Residue |
| A | ARG419 |
| A | ARG419 |
| A | HOH642 |
| A | HOH642 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | binding site for residue DQW A 503 |
| Chain | Residue |
| A | TYR426 |
| A | TYR426 |
| A | ARG440 |
| A | ARG440 |
| A | GLN443 |
| A | ASP444 |
| A | ASP444 |
| A | GLU447 |
| A | PHE448 |
| A | PHE448 |
| A | HOH629 |
| A | HOH629 |
Functional Information from PROSITE/UniProt
| site_id | PS00633 |
| Number of Residues | 60 |
| Details | BROMODOMAIN_1 Bromodomain signature. AwpFykpvDasalgvhDYHdiIkhpMdlstVkrkmenrd..Yrdaqefaadvrl.MfsNCykY |
| Chain | Residue | Details |
| A | ALA369-TYR428 |
