5O0X

Crystal structure of dehydrogenase domain of Cylindrospermum stagnale NADPH-Oxidase 5 (NOX5)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016020	cellular_component	membrane
A	0016491	molecular_function	oxidoreductase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	22
Details	binding site for residue FAD A 801

Chain	Residue
A	TYR445
A	SER482
A	TRP483
A	THR484
A	ILE538
A	THR541
A	ARG678
A	LYS690
A	TRP695
A	CL806
A	P6G811
A	HIS459
A	HOH907
A	HOH911
A	HOH938
A	PRO460
A	PHE461
A	THR462
A	HIS476
A	ARG478
A	VAL480
A	GLY481

---

site_id	AC2
Number of Residues	1
Details	binding site for residue CL A 802

Chain	Residue
A	ARG478

---

site_id	AC3
Number of Residues	1
Details	binding site for residue CL A 803

Chain	Residue
A	PEG819

---

site_id	AC4
Number of Residues	1
Details	binding site for residue CL A 804

Chain	Residue
A	PRO467

---

site_id	AC5
Number of Residues	1
Details	binding site for residue CL A 806

Chain	Residue
A	FAD801

---

site_id	AC6
Number of Residues	2
Details	binding site for residue CL A 808

Chain	Residue
A	SER482
A	LYS486

---

site_id	AC7
Number of Residues	7
Details	binding site for residue P6G A 809

Chain	Residue
A	SER412
A	LYS449
A	LYS455
A	TRP458
A	TYR513
A	GLU664
A	P6G810

---

site_id	AC8
Number of Residues	9
Details	binding site for residue P6G A 810

Chain	Residue
A	TRP458
A	ASP515
A	PRO521
A	HIS524
A	GLU527
A	SER528
A	ARG689
A	P6G809
A	PEG820

---

site_id	AC9
Number of Residues	8
Details	binding site for residue P6G A 811

Chain	Residue
A	LEU675
A	ARG678
A	TYR688
A	LYS690
A	ASN692
A	TRP695
A	FAD801
A	HOH907

---

site_id	AD1
Number of Residues	12
Details	binding site for residue P6G A 812

Chain	Residue
A	SER425
A	ARG478
A	ALA536
A	ASN572
A	ARG573
A	GLU574
A	ALA577
A	THR604
A	LEU696
A	HOH929
A	HOH934
A	HOH964

---

site_id	AD2
Number of Residues	7
Details	binding site for residue P6G A 813

Chain	Residue
A	LYS652
A	LYS656
A	LYS656
A	ALA659
A	PRO660
A	TYR684
A	GOL826

---

site_id	AD3
Number of Residues	4
Details	binding site for residue PEG A 814

Chain	Residue
A	LYS455
A	LYS683
A	GOL822
A	GOL826

---

site_id	AD4
Number of Residues	4
Details	binding site for residue PEG A 815

Chain	Residue
A	HIS552
A	GLN555
A	LYS587
A	GLU591

---

site_id	AD5
Number of Residues	7
Details	binding site for residue PEG A 816

Chain	Residue
A	LYS548
A	GLU579
A	TRP580
A	PHE581
A	VAL582
A	GLU583
A	LEU584

---

site_id	AD6
Number of Residues	4
Details	binding site for residue PEG A 817

Chain	Residue
A	PRO517
A	TYR518
A	THR520
A	HOH976

---

site_id	AD7
Number of Residues	7
Details	binding site for residue PEG A 818

Chain	Residue
A	LYS565
A	ASP592
A	ASN595
A	PHE597
A	ASP598
A	HOH924
A	HOH930

---

site_id	AD8
Number of Residues	3
Details	binding site for residue PEG A 819

Chain	Residue
A	CL803
A	LYS426
A	TYR488

---

site_id	AD9
Number of Residues	5
Details	binding site for residue PEG A 820

Chain	Residue
A	ASP661
A	ASN662
A	GLU664
A	P6G810
A	HOH913

---

site_id	AE1
Number of Residues	3
Details	binding site for residue PEG A 821

Chain	Residue
A	ASN439
A	GLN441
A	ASP444

---

site_id	AE2
Number of Residues	8
Details	binding site for residue GOL A 822

Chain	Residue
A	PHE456
A	ALA659
A	PRO660
A	ASP661
A	TYR684
A	GLY685
A	PEG814
A	HOH910

---

site_id	AE3
Number of Residues	3
Details	binding site for residue GOL A 823

Chain	Residue
A	SER425
A	LYS426
A	HOH901

---

site_id	AE4
Number of Residues	6
Details	binding site for residue GOL A 824

Chain	Residue
A	SER421
A	GLY429
A	GLN431
A	THR474
A	HIS476
A	HOH955

---

site_id	AE5
Number of Residues	6
Details	binding site for residue GOL A 825

Chain	Residue
A	VAL417
A	VAL418
A	ASN419
A	GLN494
A	GLY509
A	HOH917

---

site_id	AE6
Number of Residues	3
Details	binding site for residue GOL A 826

Chain	Residue
A	LYS683
A	P6G813
A	PEG814

---

site_id	AE7
Number of Residues	3
Details	binding site for residue GOL A 827

Chain	Residue
A	ILE650
A	ASP653
A	HOH961

---

site_id	AE8
Number of Residues	3
Details	binding site for residue PEG A 828

Chain	Residue
A	SER586
A	THR634
A	HOH986

---