Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 201 |
| Chain | Residue |
| B | LEU420 |
| C | GLN1 |
| C | SER27 |
| C | TYR109 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue EDO D 201 |
| Chain | Residue |
| D | GLU46 |
| D | ALA91 |
| D | ARG38 |
| D | GLN39 |
| D | THR40 |
| D | ASN43 |
| D | GLN44 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO D 202 |
| Chain | Residue |
| A | ARG484 |
| A | ASP526 |
| D | ARG30 |
| D | THR31 |
| D | SER53 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 601 |
| Chain | Residue |
| A | LEU272 |
| A | GLN273 |
| A | GLY274 |
| A | THR276 |
| A | HOH773 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 602 |
| Chain | Residue |
| A | ASN309 |
| A | LEU310 |
| A | ASN311 |
| A | LEU325 |
| A | HOH746 |
| A | HOH790 |
| A | HOH809 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 603 |
| Chain | Residue |
| A | PRO243 |
| A | PRO280 |
| A | THR281 |
| A | HOH780 |
| B | PRO243 |
| B | PRO280 |
| B | THR281 |
| B | HOH800 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 604 |
| Chain | Residue |
| A | PRO230 |
| A | GLU464 |
| A | HIS468 |
| A | HOH737 |
| B | GLN471 |
| B | EDO605 |
| B | EDO613 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 605 |
| Chain | Residue |
| A | GLY450 |
| A | GLY451 |
| A | HOH702 |
| B | ASN355 |
| B | ARG356 |
| B | HOH743 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 606 |
| Chain | Residue |
| A | ARG341 |
| B | PHE445 |
| B | EDO620 |
| site_id | AD1 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 607 |
| Chain | Residue |
| A | LEU279 |
| A | THR281 |
| A | GLY282 |
| A | LYS393 |
| A | HOH726 |
| A | HOH734 |
| A | HOH735 |
| B | PRO245 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 608 |
| Chain | Residue |
| A | ARG299 |
| A | SER379 |
| A | THR380 |
| A | TRP381 |
| A | HOH721 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 609 |
| Chain | Residue |
| A | GLU359 |
| A | TRP381 |
| A | LYS449 |
| B | HOH719 |
| site_id | AD4 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 610 |
| Chain | Residue |
| A | LEU352 |
| A | PRO514 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 611 |
| Chain | Residue |
| A | VAL259 |
| A | PHE441 |
| A | HOH708 |
| A | HOH715 |
| A | HOH743 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 612 |
| Chain | Residue |
| A | ARG509 |
| A | SER511 |
| A | VAL515 |
| A | VAL516 |
| A | MET538 |
| site_id | AD7 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 613 |
| Chain | Residue |
| A | LEU234 |
| A | ASP247 |
| A | VAL248 |
| A | LEU249 |
| A | VAL515 |
| A | ALA517 |
| A | THR519 |
| A | HOH709 |
| site_id | AD8 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 614 |
| Chain | Residue |
| A | LYS225 |
| A | GLN471 |
| A | GLU472 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 615 |
| Chain | Residue |
| A | ILE258 |
| A | GLN260 |
| A | TRP411 |
| A | LEU413 |
| site_id | AE1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 616 |
| Chain | Residue |
| A | HOH763 |
| B | GLY450 |
| B | GLY451 |
| A | ALA354 |
| A | ASN355 |
| A | HOH733 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 601 |
| Chain | Residue |
| B | ASN309 |
| B | LEU310 |
| B | ASN311 |
| B | HOH705 |
| B | HOH770 |
| site_id | AE3 |
| Number of Residues | 8 |
| Details | binding site for residue EDO B 602 |
| Chain | Residue |
| A | PRO245 |
| B | THR281 |
| B | GLY282 |
| B | ALA285 |
| B | LEU310 |
| B | LYS393 |
| B | HOH715 |
| B | HOH809 |
| site_id | AE4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 603 |
| Chain | Residue |
| B | LEU272 |
| B | GLN273 |
| B | GLY274 |
| B | THR276 |
| B | VAL321 |
| site_id | AE5 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 604 |
| Chain | Residue |
| A | LEU278 |
| B | GLU236 |
| B | HOH732 |
| site_id | AE6 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 605 |
| Chain | Residue |
| A | GLN471 |
| A | EDO604 |
| A | HOH737 |
| B | LEU232 |
| B | GLU464 |
| B | HIS468 |
| B | EDO613 |
| site_id | AE7 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 606 |
| Chain | Residue |
| B | ARG299 |
| B | SER379 |
| B | THR380 |
| site_id | AE8 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 607 |
| Chain | Residue |
| A | PHE445 |
| A | PRO447 |
| B | ARG341 |
| B | EDO614 |
| site_id | AE9 |
| Number of Residues | 1 |
| Details | binding site for residue EDO B 608 |
| site_id | AF1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 609 |
| Chain | Residue |
| B | GLU359 |
| B | TRP381 |
| B | LYS449 |
| site_id | AF2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 610 |
| Chain | Residue |
| A | LEU279 |
| A | HOH726 |
| B | PRO245 |
| B | ILE246 |
| B | HOH729 |
| B | HOH790 |
| site_id | AF3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 611 |
| Chain | Residue |
| B | ARG509 |
| B | SER511 |
| B | VAL516 |
| B | HOH769 |
| site_id | AF4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 612 |
| Chain | Residue |
| B | ARG484 |
| B | ASP526 |
| C | ARG30 |
| C | THR31 |
| C | SER53 |
| C | VAL54 |
| site_id | AF5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 613 |
| Chain | Residue |
| A | EDO604 |
| B | HIS468 |
| B | GLN471 |
| B | GLU472 |
| B | EDO605 |
| site_id | AF6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 614 |
| Chain | Residue |
| B | ARG287 |
| B | LYS393 |
| B | EDO607 |
| B | HOH738 |
| site_id | AF7 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 615 |
| Chain | Residue |
| A | ILE231 |
| B | TYR470 |
| B | HOH773 |
| site_id | AF8 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 616 |
| Chain | Residue |
| B | ASP296 |
| B | GLU297 |
| B | HIS298 |
| B | GLY300 |
| site_id | AF9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 617 |
| Chain | Residue |
| B | SER417 |
| B | HOH741 |
| B | HOH746 |
| B | HOH757 |
| C | ASP108 |
| site_id | AG1 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 618 |
| Chain | Residue |
| B | VAL515 |
| B | ALA517 |
| site_id | AG2 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 619 |
| Chain | Residue |
| B | THR493 |
| B | GLU496 |
| site_id | AG3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 620 |
| Chain | Residue |
| A | EDO606 |
| B | PRO245 |
| B | ASP247 |
| B | HOH712 |
