Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5NWL

Crystal structure of a human RAD51-ATP filament.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000150	molecular_function	DNA strand exchange activity
A	0000152	cellular_component	nuclear ubiquitin ligase complex
A	0000166	molecular_function	nucleotide binding
A	0000228	cellular_component	nuclear chromosome
A	0000722	biological_process	telomere maintenance via recombination
A	0000724	biological_process	double-strand break repair via homologous recombination
A	0000730	biological_process	DNA recombinase assembly
A	0000781	cellular_component	chromosome, telomeric region
A	0000785	cellular_component	chromatin
A	0000793	cellular_component	condensed chromosome
A	0000794	cellular_component	condensed nuclear chromosome
A	0000800	cellular_component	lateral element
A	0001673	cellular_component	male germ cell nucleus
A	0003677	molecular_function	DNA binding
A	0003682	molecular_function	chromatin binding
A	0003690	molecular_function	double-stranded DNA binding
A	0003697	molecular_function	single-stranded DNA binding
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005694	cellular_component	chromosome
A	0005730	cellular_component	nucleolus
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005759	cellular_component	mitochondrial matrix
A	0005813	cellular_component	centrosome
A	0005829	cellular_component	cytosol
A	0005856	cellular_component	cytoskeleton
A	0006259	biological_process	DNA metabolic process
A	0006281	biological_process	DNA repair
A	0006310	biological_process	DNA recombination
A	0006312	biological_process	mitotic recombination
A	0006974	biological_process	DNA damage response
A	0007127	biological_process	meiosis I
A	0007131	biological_process	reciprocal meiotic recombination
A	0008094	molecular_function	ATP-dependent activity, acting on DNA
A	0009410	biological_process	response to xenobiotic stimulus
A	0009636	biological_process	response to toxic substance
A	0010165	biological_process	response to X-ray
A	0010569	biological_process	regulation of double-strand break repair via homologous recombination
A	0010833	biological_process	telomere maintenance via telomere lengthening
A	0016605	cellular_component	PML body
A	0017116	molecular_function	single-stranded DNA helicase activity
A	0019899	molecular_function	enzyme binding
A	0031297	biological_process	replication fork processing
A	0032200	biological_process	telomere organization
A	0032991	cellular_component	protein-containing complex
A	0035861	cellular_component	site of double-strand break
A	0036297	biological_process	interstrand cross-link repair
A	0042148	biological_process	DNA strand invasion
A	0042802	molecular_function	identical protein binding
A	0048471	cellular_component	perinuclear region of cytoplasm
A	0051321	biological_process	meiotic cell cycle
A	0070182	molecular_function	DNA polymerase binding
A	0070192	biological_process	chromosome organization involved in meiotic cell cycle
A	0071312	biological_process	cellular response to alkaloid
A	0071479	biological_process	cellular response to ionizing radiation
A	0071480	biological_process	cellular response to gamma radiation
A	0072711	biological_process	cellular response to hydroxyurea
A	0072719	biological_process	cellular response to cisplatin
A	0072757	biological_process	cellular response to camptothecin
A	0099182	cellular_component	presynaptic intermediate filament cytoskeleton
A	0140664	molecular_function	ATP-dependent DNA damage sensor activity
A	1904631	biological_process	response to glucoside
A	1990414	biological_process	replication-born double-strand break repair via sister chromatid exchange
A	1990426	biological_process	mitotic recombination-dependent replication fork processing
A	1990918	biological_process	double-strand break repair involved in meiotic recombination
A	2000001	biological_process	regulation of DNA damage checkpoint
B	0000150	molecular_function	DNA strand exchange activity
B	0000152	cellular_component	nuclear ubiquitin ligase complex
B	0000166	molecular_function	nucleotide binding
B	0000228	cellular_component	nuclear chromosome
B	0000722	biological_process	telomere maintenance via recombination
B	0000724	biological_process	double-strand break repair via homologous recombination
B	0000730	biological_process	DNA recombinase assembly
B	0000781	cellular_component	chromosome, telomeric region
B	0000785	cellular_component	chromatin
B	0000793	cellular_component	condensed chromosome
B	0000794	cellular_component	condensed nuclear chromosome
B	0000800	cellular_component	lateral element
B	0001673	cellular_component	male germ cell nucleus
B	0003677	molecular_function	DNA binding
B	0003682	molecular_function	chromatin binding
B	0003690	molecular_function	double-stranded DNA binding
B	0003697	molecular_function	single-stranded DNA binding
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005694	cellular_component	chromosome
B	0005730	cellular_component	nucleolus
B	0005737	cellular_component	cytoplasm
B	0005739	cellular_component	mitochondrion
B	0005759	cellular_component	mitochondrial matrix
B	0005813	cellular_component	centrosome
B	0005829	cellular_component	cytosol
B	0005856	cellular_component	cytoskeleton
B	0006259	biological_process	DNA metabolic process
B	0006281	biological_process	DNA repair
B	0006310	biological_process	DNA recombination
B	0006312	biological_process	mitotic recombination
B	0006974	biological_process	DNA damage response
B	0007127	biological_process	meiosis I
B	0007131	biological_process	reciprocal meiotic recombination
B	0008094	molecular_function	ATP-dependent activity, acting on DNA
B	0009410	biological_process	response to xenobiotic stimulus
B	0009636	biological_process	response to toxic substance
B	0010165	biological_process	response to X-ray
B	0010569	biological_process	regulation of double-strand break repair via homologous recombination
B	0010833	biological_process	telomere maintenance via telomere lengthening
B	0016605	cellular_component	PML body
B	0017116	molecular_function	single-stranded DNA helicase activity
B	0019899	molecular_function	enzyme binding
B	0031297	biological_process	replication fork processing
B	0032200	biological_process	telomere organization
B	0032991	cellular_component	protein-containing complex
B	0035861	cellular_component	site of double-strand break
B	0036297	biological_process	interstrand cross-link repair
B	0042148	biological_process	DNA strand invasion
B	0042802	molecular_function	identical protein binding
B	0048471	cellular_component	perinuclear region of cytoplasm
B	0051321	biological_process	meiotic cell cycle
B	0070182	molecular_function	DNA polymerase binding
B	0070192	biological_process	chromosome organization involved in meiotic cell cycle
B	0071312	biological_process	cellular response to alkaloid
B	0071479	biological_process	cellular response to ionizing radiation
B	0071480	biological_process	cellular response to gamma radiation
B	0072711	biological_process	cellular response to hydroxyurea
B	0072719	biological_process	cellular response to cisplatin
B	0072757	biological_process	cellular response to camptothecin
B	0099182	cellular_component	presynaptic intermediate filament cytoskeleton
B	0140664	molecular_function	ATP-dependent DNA damage sensor activity
B	1904631	biological_process	response to glucoside
B	1990414	biological_process	replication-born double-strand break repair via sister chromatid exchange
B	1990426	biological_process	mitotic recombination-dependent replication fork processing
B	1990918	biological_process	double-strand break repair involved in meiotic recombination
B	2000001	biological_process	regulation of DNA damage checkpoint
C	0000150	molecular_function	DNA strand exchange activity
C	0000152	cellular_component	nuclear ubiquitin ligase complex
C	0000166	molecular_function	nucleotide binding
C	0000228	cellular_component	nuclear chromosome
C	0000722	biological_process	telomere maintenance via recombination
C	0000724	biological_process	double-strand break repair via homologous recombination
C	0000730	biological_process	DNA recombinase assembly
C	0000781	cellular_component	chromosome, telomeric region
C	0000785	cellular_component	chromatin
C	0000793	cellular_component	condensed chromosome
C	0000794	cellular_component	condensed nuclear chromosome
C	0000800	cellular_component	lateral element
C	0001673	cellular_component	male germ cell nucleus
C	0003677	molecular_function	DNA binding
C	0003682	molecular_function	chromatin binding
C	0003690	molecular_function	double-stranded DNA binding
C	0003697	molecular_function	single-stranded DNA binding
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005694	cellular_component	chromosome
C	0005730	cellular_component	nucleolus
C	0005737	cellular_component	cytoplasm
C	0005739	cellular_component	mitochondrion
C	0005759	cellular_component	mitochondrial matrix
C	0005813	cellular_component	centrosome
C	0005829	cellular_component	cytosol
C	0005856	cellular_component	cytoskeleton
C	0006259	biological_process	DNA metabolic process
C	0006281	biological_process	DNA repair
C	0006310	biological_process	DNA recombination
C	0006312	biological_process	mitotic recombination
C	0006974	biological_process	DNA damage response
C	0007127	biological_process	meiosis I
C	0007131	biological_process	reciprocal meiotic recombination
C	0008094	molecular_function	ATP-dependent activity, acting on DNA
C	0009410	biological_process	response to xenobiotic stimulus
C	0009636	biological_process	response to toxic substance
C	0010165	biological_process	response to X-ray
C	0010569	biological_process	regulation of double-strand break repair via homologous recombination
C	0010833	biological_process	telomere maintenance via telomere lengthening
C	0016605	cellular_component	PML body
C	0017116	molecular_function	single-stranded DNA helicase activity
C	0019899	molecular_function	enzyme binding
C	0031297	biological_process	replication fork processing
C	0032200	biological_process	telomere organization
C	0032991	cellular_component	protein-containing complex
C	0035861	cellular_component	site of double-strand break
C	0036297	biological_process	interstrand cross-link repair
C	0042148	biological_process	DNA strand invasion
C	0042802	molecular_function	identical protein binding
C	0048471	cellular_component	perinuclear region of cytoplasm
C	0051321	biological_process	meiotic cell cycle
C	0070182	molecular_function	DNA polymerase binding
C	0070192	biological_process	chromosome organization involved in meiotic cell cycle
C	0071312	biological_process	cellular response to alkaloid
C	0071479	biological_process	cellular response to ionizing radiation
C	0071480	biological_process	cellular response to gamma radiation
C	0072711	biological_process	cellular response to hydroxyurea
C	0072719	biological_process	cellular response to cisplatin
C	0072757	biological_process	cellular response to camptothecin
C	0099182	cellular_component	presynaptic intermediate filament cytoskeleton
C	0140664	molecular_function	ATP-dependent DNA damage sensor activity
C	1904631	biological_process	response to glucoside
C	1990414	biological_process	replication-born double-strand break repair via sister chromatid exchange
C	1990426	biological_process	mitotic recombination-dependent replication fork processing
C	1990918	biological_process	double-strand break repair involved in meiotic recombination
C	2000001	biological_process	regulation of DNA damage checkpoint
D	0000150	molecular_function	DNA strand exchange activity
D	0000152	cellular_component	nuclear ubiquitin ligase complex
D	0000166	molecular_function	nucleotide binding
D	0000228	cellular_component	nuclear chromosome
D	0000722	biological_process	telomere maintenance via recombination
D	0000724	biological_process	double-strand break repair via homologous recombination
D	0000730	biological_process	DNA recombinase assembly
D	0000781	cellular_component	chromosome, telomeric region
D	0000785	cellular_component	chromatin
D	0000793	cellular_component	condensed chromosome
D	0000794	cellular_component	condensed nuclear chromosome
D	0000800	cellular_component	lateral element
D	0001673	cellular_component	male germ cell nucleus
D	0003677	molecular_function	DNA binding
D	0003682	molecular_function	chromatin binding
D	0003690	molecular_function	double-stranded DNA binding
D	0003697	molecular_function	single-stranded DNA binding
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005694	cellular_component	chromosome
D	0005730	cellular_component	nucleolus
D	0005737	cellular_component	cytoplasm
D	0005739	cellular_component	mitochondrion
D	0005759	cellular_component	mitochondrial matrix
D	0005813	cellular_component	centrosome
D	0005829	cellular_component	cytosol
D	0005856	cellular_component	cytoskeleton
D	0006259	biological_process	DNA metabolic process
D	0006281	biological_process	DNA repair
D	0006310	biological_process	DNA recombination
D	0006312	biological_process	mitotic recombination
D	0006974	biological_process	DNA damage response
D	0007127	biological_process	meiosis I
D	0007131	biological_process	reciprocal meiotic recombination
D	0008094	molecular_function	ATP-dependent activity, acting on DNA
D	0009410	biological_process	response to xenobiotic stimulus
D	0009636	biological_process	response to toxic substance
D	0010165	biological_process	response to X-ray
D	0010569	biological_process	regulation of double-strand break repair via homologous recombination
D	0010833	biological_process	telomere maintenance via telomere lengthening
D	0016605	cellular_component	PML body
D	0017116	molecular_function	single-stranded DNA helicase activity
D	0019899	molecular_function	enzyme binding
D	0031297	biological_process	replication fork processing
D	0032200	biological_process	telomere organization
D	0032991	cellular_component	protein-containing complex
D	0035861	cellular_component	site of double-strand break
D	0036297	biological_process	interstrand cross-link repair
D	0042148	biological_process	DNA strand invasion
D	0042802	molecular_function	identical protein binding
D	0048471	cellular_component	perinuclear region of cytoplasm
D	0051321	biological_process	meiotic cell cycle
D	0070182	molecular_function	DNA polymerase binding
D	0070192	biological_process	chromosome organization involved in meiotic cell cycle
D	0071312	biological_process	cellular response to alkaloid
D	0071479	biological_process	cellular response to ionizing radiation
D	0071480	biological_process	cellular response to gamma radiation
D	0072711	biological_process	cellular response to hydroxyurea
D	0072719	biological_process	cellular response to cisplatin
D	0072757	biological_process	cellular response to camptothecin
D	0099182	cellular_component	presynaptic intermediate filament cytoskeleton
D	0140664	molecular_function	ATP-dependent DNA damage sensor activity
D	1904631	biological_process	response to glucoside
D	1990414	biological_process	replication-born double-strand break repair via sister chromatid exchange
D	1990426	biological_process	mitotic recombination-dependent replication fork processing
D	1990918	biological_process	double-strand break repair involved in meiotic recombination
D	2000001	biological_process	regulation of DNA damage checkpoint
E	0000150	molecular_function	DNA strand exchange activity
E	0000152	cellular_component	nuclear ubiquitin ligase complex
E	0000166	molecular_function	nucleotide binding
E	0000228	cellular_component	nuclear chromosome
E	0000722	biological_process	telomere maintenance via recombination
E	0000724	biological_process	double-strand break repair via homologous recombination
E	0000730	biological_process	DNA recombinase assembly
E	0000781	cellular_component	chromosome, telomeric region
E	0000785	cellular_component	chromatin
E	0000793	cellular_component	condensed chromosome
E	0000794	cellular_component	condensed nuclear chromosome
E	0000800	cellular_component	lateral element
E	0001673	cellular_component	male germ cell nucleus
E	0003677	molecular_function	DNA binding
E	0003682	molecular_function	chromatin binding
E	0003690	molecular_function	double-stranded DNA binding
E	0003697	molecular_function	single-stranded DNA binding
E	0005515	molecular_function	protein binding
E	0005524	molecular_function	ATP binding
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005694	cellular_component	chromosome
E	0005730	cellular_component	nucleolus
E	0005737	cellular_component	cytoplasm
E	0005739	cellular_component	mitochondrion
E	0005759	cellular_component	mitochondrial matrix
E	0005813	cellular_component	centrosome
E	0005829	cellular_component	cytosol
E	0005856	cellular_component	cytoskeleton
E	0006259	biological_process	DNA metabolic process
E	0006281	biological_process	DNA repair
E	0006310	biological_process	DNA recombination
E	0006312	biological_process	mitotic recombination
E	0006974	biological_process	DNA damage response
E	0007127	biological_process	meiosis I
E	0007131	biological_process	reciprocal meiotic recombination
E	0008094	molecular_function	ATP-dependent activity, acting on DNA
E	0009410	biological_process	response to xenobiotic stimulus
E	0009636	biological_process	response to toxic substance
E	0010165	biological_process	response to X-ray
E	0010569	biological_process	regulation of double-strand break repair via homologous recombination
E	0010833	biological_process	telomere maintenance via telomere lengthening
E	0016605	cellular_component	PML body
E	0017116	molecular_function	single-stranded DNA helicase activity
E	0019899	molecular_function	enzyme binding
E	0031297	biological_process	replication fork processing
E	0032200	biological_process	telomere organization
E	0032991	cellular_component	protein-containing complex
E	0035861	cellular_component	site of double-strand break
E	0036297	biological_process	interstrand cross-link repair
E	0042148	biological_process	DNA strand invasion
E	0042802	molecular_function	identical protein binding
E	0048471	cellular_component	perinuclear region of cytoplasm
E	0051321	biological_process	meiotic cell cycle
E	0070182	molecular_function	DNA polymerase binding
E	0070192	biological_process	chromosome organization involved in meiotic cell cycle
E	0071312	biological_process	cellular response to alkaloid
E	0071479	biological_process	cellular response to ionizing radiation
E	0071480	biological_process	cellular response to gamma radiation
E	0072711	biological_process	cellular response to hydroxyurea
E	0072719	biological_process	cellular response to cisplatin
E	0072757	biological_process	cellular response to camptothecin
E	0099182	cellular_component	presynaptic intermediate filament cytoskeleton
E	0140664	molecular_function	ATP-dependent DNA damage sensor activity
E	1904631	biological_process	response to glucoside
E	1990414	biological_process	replication-born double-strand break repair via sister chromatid exchange
E	1990426	biological_process	mitotic recombination-dependent replication fork processing
E	1990918	biological_process	double-strand break repair involved in meiotic recombination
E	2000001	biological_process	regulation of DNA damage checkpoint
F	0000150	molecular_function	DNA strand exchange activity
F	0000152	cellular_component	nuclear ubiquitin ligase complex
F	0000166	molecular_function	nucleotide binding
F	0000228	cellular_component	nuclear chromosome
F	0000722	biological_process	telomere maintenance via recombination
F	0000724	biological_process	double-strand break repair via homologous recombination
F	0000730	biological_process	DNA recombinase assembly
F	0000781	cellular_component	chromosome, telomeric region
F	0000785	cellular_component	chromatin
F	0000793	cellular_component	condensed chromosome
F	0000794	cellular_component	condensed nuclear chromosome
F	0000800	cellular_component	lateral element
F	0001673	cellular_component	male germ cell nucleus
F	0003677	molecular_function	DNA binding
F	0003682	molecular_function	chromatin binding
F	0003690	molecular_function	double-stranded DNA binding
F	0003697	molecular_function	single-stranded DNA binding
F	0005515	molecular_function	protein binding
F	0005524	molecular_function	ATP binding
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005694	cellular_component	chromosome
F	0005730	cellular_component	nucleolus
F	0005737	cellular_component	cytoplasm
F	0005739	cellular_component	mitochondrion
F	0005759	cellular_component	mitochondrial matrix
F	0005813	cellular_component	centrosome
F	0005829	cellular_component	cytosol
F	0005856	cellular_component	cytoskeleton
F	0006259	biological_process	DNA metabolic process
F	0006281	biological_process	DNA repair
F	0006310	biological_process	DNA recombination
F	0006312	biological_process	mitotic recombination
F	0006974	biological_process	DNA damage response
F	0007127	biological_process	meiosis I
F	0007131	biological_process	reciprocal meiotic recombination
F	0008094	molecular_function	ATP-dependent activity, acting on DNA
F	0009410	biological_process	response to xenobiotic stimulus
F	0009636	biological_process	response to toxic substance
F	0010165	biological_process	response to X-ray
F	0010569	biological_process	regulation of double-strand break repair via homologous recombination
F	0010833	biological_process	telomere maintenance via telomere lengthening
F	0016605	cellular_component	PML body
F	0017116	molecular_function	single-stranded DNA helicase activity
F	0019899	molecular_function	enzyme binding
F	0031297	biological_process	replication fork processing
F	0032200	biological_process	telomere organization
F	0032991	cellular_component	protein-containing complex
F	0035861	cellular_component	site of double-strand break
F	0036297	biological_process	interstrand cross-link repair
F	0042148	biological_process	DNA strand invasion
F	0042802	molecular_function	identical protein binding
F	0048471	cellular_component	perinuclear region of cytoplasm
F	0051321	biological_process	meiotic cell cycle
F	0070182	molecular_function	DNA polymerase binding
F	0070192	biological_process	chromosome organization involved in meiotic cell cycle
F	0071312	biological_process	cellular response to alkaloid
F	0071479	biological_process	cellular response to ionizing radiation
F	0071480	biological_process	cellular response to gamma radiation
F	0072711	biological_process	cellular response to hydroxyurea
F	0072719	biological_process	cellular response to cisplatin
F	0072757	biological_process	cellular response to camptothecin
F	0099182	cellular_component	presynaptic intermediate filament cytoskeleton
F	0140664	molecular_function	ATP-dependent DNA damage sensor activity
F	1904631	biological_process	response to glucoside
F	1990414	biological_process	replication-born double-strand break repair via sister chromatid exchange
F	1990426	biological_process	mitotic recombination-dependent replication fork processing
F	1990918	biological_process	double-strand break repair involved in meiotic recombination
F	2000001	biological_process	regulation of DNA damage checkpoint
G	0000150	molecular_function	DNA strand exchange activity
G	0000152	cellular_component	nuclear ubiquitin ligase complex
G	0000166	molecular_function	nucleotide binding
G	0000228	cellular_component	nuclear chromosome
G	0000722	biological_process	telomere maintenance via recombination
G	0000724	biological_process	double-strand break repair via homologous recombination
G	0000730	biological_process	DNA recombinase assembly
G	0000781	cellular_component	chromosome, telomeric region
G	0000785	cellular_component	chromatin
G	0000793	cellular_component	condensed chromosome
G	0000794	cellular_component	condensed nuclear chromosome
G	0000800	cellular_component	lateral element
G	0001673	cellular_component	male germ cell nucleus
G	0003677	molecular_function	DNA binding
G	0003682	molecular_function	chromatin binding
G	0003690	molecular_function	double-stranded DNA binding
G	0003697	molecular_function	single-stranded DNA binding
G	0005515	molecular_function	protein binding
G	0005524	molecular_function	ATP binding
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005694	cellular_component	chromosome
G	0005730	cellular_component	nucleolus
G	0005737	cellular_component	cytoplasm
G	0005739	cellular_component	mitochondrion
G	0005759	cellular_component	mitochondrial matrix
G	0005813	cellular_component	centrosome
G	0005829	cellular_component	cytosol
G	0005856	cellular_component	cytoskeleton
G	0006259	biological_process	DNA metabolic process
G	0006281	biological_process	DNA repair
G	0006310	biological_process	DNA recombination
G	0006312	biological_process	mitotic recombination
G	0006974	biological_process	DNA damage response
G	0007127	biological_process	meiosis I
G	0007131	biological_process	reciprocal meiotic recombination
G	0008094	molecular_function	ATP-dependent activity, acting on DNA
G	0009410	biological_process	response to xenobiotic stimulus
G	0009636	biological_process	response to toxic substance
G	0010165	biological_process	response to X-ray
G	0010569	biological_process	regulation of double-strand break repair via homologous recombination
G	0010833	biological_process	telomere maintenance via telomere lengthening
G	0016605	cellular_component	PML body
G	0017116	molecular_function	single-stranded DNA helicase activity
G	0019899	molecular_function	enzyme binding
G	0031297	biological_process	replication fork processing
G	0032200	biological_process	telomere organization
G	0032991	cellular_component	protein-containing complex
G	0035861	cellular_component	site of double-strand break
G	0036297	biological_process	interstrand cross-link repair
G	0042148	biological_process	DNA strand invasion
G	0042802	molecular_function	identical protein binding
G	0048471	cellular_component	perinuclear region of cytoplasm
G	0051321	biological_process	meiotic cell cycle
G	0070182	molecular_function	DNA polymerase binding
G	0070192	biological_process	chromosome organization involved in meiotic cell cycle
G	0071312	biological_process	cellular response to alkaloid
G	0071479	biological_process	cellular response to ionizing radiation
G	0071480	biological_process	cellular response to gamma radiation
G	0072711	biological_process	cellular response to hydroxyurea
G	0072719	biological_process	cellular response to cisplatin
G	0072757	biological_process	cellular response to camptothecin
G	0099182	cellular_component	presynaptic intermediate filament cytoskeleton
G	0140664	molecular_function	ATP-dependent DNA damage sensor activity
G	1904631	biological_process	response to glucoside
G	1990414	biological_process	replication-born double-strand break repair via sister chromatid exchange
G	1990426	biological_process	mitotic recombination-dependent replication fork processing
G	1990918	biological_process	double-strand break repair involved in meiotic recombination
G	2000001	biological_process	regulation of DNA damage checkpoint
H	0000150	molecular_function	DNA strand exchange activity
H	0000152	cellular_component	nuclear ubiquitin ligase complex
H	0000166	molecular_function	nucleotide binding
H	0000228	cellular_component	nuclear chromosome
H	0000722	biological_process	telomere maintenance via recombination
H	0000724	biological_process	double-strand break repair via homologous recombination
H	0000730	biological_process	DNA recombinase assembly
H	0000781	cellular_component	chromosome, telomeric region
H	0000785	cellular_component	chromatin
H	0000793	cellular_component	condensed chromosome
H	0000794	cellular_component	condensed nuclear chromosome
H	0000800	cellular_component	lateral element
H	0001673	cellular_component	male germ cell nucleus
H	0003677	molecular_function	DNA binding
H	0003682	molecular_function	chromatin binding
H	0003690	molecular_function	double-stranded DNA binding
H	0003697	molecular_function	single-stranded DNA binding
H	0005515	molecular_function	protein binding
H	0005524	molecular_function	ATP binding
H	0005634	cellular_component	nucleus
H	0005654	cellular_component	nucleoplasm
H	0005694	cellular_component	chromosome
H	0005730	cellular_component	nucleolus
H	0005737	cellular_component	cytoplasm
H	0005739	cellular_component	mitochondrion
H	0005759	cellular_component	mitochondrial matrix
H	0005813	cellular_component	centrosome
H	0005829	cellular_component	cytosol
H	0005856	cellular_component	cytoskeleton
H	0006259	biological_process	DNA metabolic process
H	0006281	biological_process	DNA repair
H	0006310	biological_process	DNA recombination
H	0006312	biological_process	mitotic recombination
H	0006974	biological_process	DNA damage response
H	0007127	biological_process	meiosis I
H	0007131	biological_process	reciprocal meiotic recombination
H	0008094	molecular_function	ATP-dependent activity, acting on DNA
H	0009410	biological_process	response to xenobiotic stimulus
H	0009636	biological_process	response to toxic substance
H	0010165	biological_process	response to X-ray
H	0010569	biological_process	regulation of double-strand break repair via homologous recombination
H	0010833	biological_process	telomere maintenance via telomere lengthening
H	0016605	cellular_component	PML body
H	0017116	molecular_function	single-stranded DNA helicase activity
H	0019899	molecular_function	enzyme binding
H	0031297	biological_process	replication fork processing
H	0032200	biological_process	telomere organization
H	0032991	cellular_component	protein-containing complex
H	0035861	cellular_component	site of double-strand break
H	0036297	biological_process	interstrand cross-link repair
H	0042148	biological_process	DNA strand invasion
H	0042802	molecular_function	identical protein binding
H	0048471	cellular_component	perinuclear region of cytoplasm
H	0051321	biological_process	meiotic cell cycle
H	0070182	molecular_function	DNA polymerase binding
H	0070192	biological_process	chromosome organization involved in meiotic cell cycle
H	0071312	biological_process	cellular response to alkaloid
H	0071479	biological_process	cellular response to ionizing radiation
H	0071480	biological_process	cellular response to gamma radiation
H	0072711	biological_process	cellular response to hydroxyurea
H	0072719	biological_process	cellular response to cisplatin
H	0072757	biological_process	cellular response to camptothecin
H	0099182	cellular_component	presynaptic intermediate filament cytoskeleton
H	0140664	molecular_function	ATP-dependent DNA damage sensor activity
H	1904631	biological_process	response to glucoside
H	1990414	biological_process	replication-born double-strand break repair via sister chromatid exchange
H	1990426	biological_process	mitotic recombination-dependent replication fork processing
H	1990918	biological_process	double-strand break repair involved in meiotic recombination
H	2000001	biological_process	regulation of DNA damage checkpoint
I	0000150	molecular_function	DNA strand exchange activity
I	0000152	cellular_component	nuclear ubiquitin ligase complex
I	0000166	molecular_function	nucleotide binding
I	0000228	cellular_component	nuclear chromosome
I	0000722	biological_process	telomere maintenance via recombination
I	0000724	biological_process	double-strand break repair via homologous recombination
I	0000730	biological_process	DNA recombinase assembly
I	0000781	cellular_component	chromosome, telomeric region
I	0000785	cellular_component	chromatin
I	0000793	cellular_component	condensed chromosome
I	0000794	cellular_component	condensed nuclear chromosome
I	0000800	cellular_component	lateral element
I	0001673	cellular_component	male germ cell nucleus
I	0003677	molecular_function	DNA binding
I	0003682	molecular_function	chromatin binding
I	0003690	molecular_function	double-stranded DNA binding
I	0003697	molecular_function	single-stranded DNA binding
I	0005515	molecular_function	protein binding
I	0005524	molecular_function	ATP binding
I	0005634	cellular_component	nucleus
I	0005654	cellular_component	nucleoplasm
I	0005694	cellular_component	chromosome
I	0005730	cellular_component	nucleolus
I	0005737	cellular_component	cytoplasm
I	0005739	cellular_component	mitochondrion
I	0005759	cellular_component	mitochondrial matrix
I	0005813	cellular_component	centrosome
I	0005829	cellular_component	cytosol
I	0005856	cellular_component	cytoskeleton
I	0006259	biological_process	DNA metabolic process
I	0006281	biological_process	DNA repair
I	0006310	biological_process	DNA recombination
I	0006312	biological_process	mitotic recombination
I	0006974	biological_process	DNA damage response
I	0007127	biological_process	meiosis I
I	0007131	biological_process	reciprocal meiotic recombination
I	0008094	molecular_function	ATP-dependent activity, acting on DNA
I	0009410	biological_process	response to xenobiotic stimulus
I	0009636	biological_process	response to toxic substance
I	0010165	biological_process	response to X-ray
I	0010569	biological_process	regulation of double-strand break repair via homologous recombination
I	0010833	biological_process	telomere maintenance via telomere lengthening
I	0016605	cellular_component	PML body
I	0017116	molecular_function	single-stranded DNA helicase activity
I	0019899	molecular_function	enzyme binding
I	0031297	biological_process	replication fork processing
I	0032200	biological_process	telomere organization
I	0032991	cellular_component	protein-containing complex
I	0035861	cellular_component	site of double-strand break
I	0036297	biological_process	interstrand cross-link repair
I	0042148	biological_process	DNA strand invasion
I	0042802	molecular_function	identical protein binding
I	0048471	cellular_component	perinuclear region of cytoplasm
I	0051321	biological_process	meiotic cell cycle
I	0070182	molecular_function	DNA polymerase binding
I	0070192	biological_process	chromosome organization involved in meiotic cell cycle
I	0071312	biological_process	cellular response to alkaloid
I	0071479	biological_process	cellular response to ionizing radiation
I	0071480	biological_process	cellular response to gamma radiation
I	0072711	biological_process	cellular response to hydroxyurea
I	0072719	biological_process	cellular response to cisplatin
I	0072757	biological_process	cellular response to camptothecin
I	0099182	cellular_component	presynaptic intermediate filament cytoskeleton
I	0140664	molecular_function	ATP-dependent DNA damage sensor activity
I	1904631	biological_process	response to glucoside
I	1990414	biological_process	replication-born double-strand break repair via sister chromatid exchange
I	1990426	biological_process	mitotic recombination-dependent replication fork processing
I	1990918	biological_process	double-strand break repair involved in meiotic recombination
I	2000001	biological_process	regulation of DNA damage checkpoint
J	0000150	molecular_function	DNA strand exchange activity
J	0000152	cellular_component	nuclear ubiquitin ligase complex
J	0000166	molecular_function	nucleotide binding
J	0000228	cellular_component	nuclear chromosome
J	0000722	biological_process	telomere maintenance via recombination
J	0000724	biological_process	double-strand break repair via homologous recombination
J	0000730	biological_process	DNA recombinase assembly
J	0000781	cellular_component	chromosome, telomeric region
J	0000785	cellular_component	chromatin
J	0000793	cellular_component	condensed chromosome
J	0000794	cellular_component	condensed nuclear chromosome
J	0000800	cellular_component	lateral element
J	0001673	cellular_component	male germ cell nucleus
J	0003677	molecular_function	DNA binding
J	0003682	molecular_function	chromatin binding
J	0003690	molecular_function	double-stranded DNA binding
J	0003697	molecular_function	single-stranded DNA binding
J	0005515	molecular_function	protein binding
J	0005524	molecular_function	ATP binding
J	0005634	cellular_component	nucleus
J	0005654	cellular_component	nucleoplasm
J	0005694	cellular_component	chromosome
J	0005730	cellular_component	nucleolus
J	0005737	cellular_component	cytoplasm
J	0005739	cellular_component	mitochondrion
J	0005759	cellular_component	mitochondrial matrix
J	0005813	cellular_component	centrosome
J	0005829	cellular_component	cytosol
J	0005856	cellular_component	cytoskeleton
J	0006259	biological_process	DNA metabolic process
J	0006281	biological_process	DNA repair
J	0006310	biological_process	DNA recombination
J	0006312	biological_process	mitotic recombination
J	0006974	biological_process	DNA damage response
J	0007127	biological_process	meiosis I
J	0007131	biological_process	reciprocal meiotic recombination
J	0008094	molecular_function	ATP-dependent activity, acting on DNA
J	0009410	biological_process	response to xenobiotic stimulus
J	0009636	biological_process	response to toxic substance
J	0010165	biological_process	response to X-ray
J	0010569	biological_process	regulation of double-strand break repair via homologous recombination
J	0010833	biological_process	telomere maintenance via telomere lengthening
J	0016605	cellular_component	PML body
J	0017116	molecular_function	single-stranded DNA helicase activity
J	0019899	molecular_function	enzyme binding
J	0031297	biological_process	replication fork processing
J	0032200	biological_process	telomere organization
J	0032991	cellular_component	protein-containing complex
J	0035861	cellular_component	site of double-strand break
J	0036297	biological_process	interstrand cross-link repair
J	0042148	biological_process	DNA strand invasion
J	0042802	molecular_function	identical protein binding
J	0048471	cellular_component	perinuclear region of cytoplasm
J	0051321	biological_process	meiotic cell cycle
J	0070182	molecular_function	DNA polymerase binding
J	0070192	biological_process	chromosome organization involved in meiotic cell cycle
J	0071312	biological_process	cellular response to alkaloid
J	0071479	biological_process	cellular response to ionizing radiation
J	0071480	biological_process	cellular response to gamma radiation
J	0072711	biological_process	cellular response to hydroxyurea
J	0072719	biological_process	cellular response to cisplatin
J	0072757	biological_process	cellular response to camptothecin
J	0099182	cellular_component	presynaptic intermediate filament cytoskeleton
J	0140664	molecular_function	ATP-dependent DNA damage sensor activity
J	1904631	biological_process	response to glucoside
J	1990414	biological_process	replication-born double-strand break repair via sister chromatid exchange
J	1990426	biological_process	mitotic recombination-dependent replication fork processing
J	1990918	biological_process	double-strand break repair involved in meiotic recombination
J	2000001	biological_process	regulation of DNA damage checkpoint
K	0000150	molecular_function	DNA strand exchange activity
K	0000152	cellular_component	nuclear ubiquitin ligase complex
K	0000166	molecular_function	nucleotide binding
K	0000228	cellular_component	nuclear chromosome
K	0000722	biological_process	telomere maintenance via recombination
K	0000724	biological_process	double-strand break repair via homologous recombination
K	0000730	biological_process	DNA recombinase assembly
K	0000781	cellular_component	chromosome, telomeric region
K	0000785	cellular_component	chromatin
K	0000793	cellular_component	condensed chromosome
K	0000794	cellular_component	condensed nuclear chromosome
K	0000800	cellular_component	lateral element
K	0001673	cellular_component	male germ cell nucleus
K	0003677	molecular_function	DNA binding
K	0003682	molecular_function	chromatin binding
K	0003690	molecular_function	double-stranded DNA binding
K	0003697	molecular_function	single-stranded DNA binding
K	0005515	molecular_function	protein binding
K	0005524	molecular_function	ATP binding
K	0005634	cellular_component	nucleus
K	0005654	cellular_component	nucleoplasm
K	0005694	cellular_component	chromosome
K	0005730	cellular_component	nucleolus
K	0005737	cellular_component	cytoplasm
K	0005739	cellular_component	mitochondrion
K	0005759	cellular_component	mitochondrial matrix
K	0005813	cellular_component	centrosome
K	0005829	cellular_component	cytosol
K	0005856	cellular_component	cytoskeleton
K	0006259	biological_process	DNA metabolic process
K	0006281	biological_process	DNA repair
K	0006310	biological_process	DNA recombination
K	0006312	biological_process	mitotic recombination
K	0006974	biological_process	DNA damage response
K	0007127	biological_process	meiosis I
K	0007131	biological_process	reciprocal meiotic recombination
K	0008094	molecular_function	ATP-dependent activity, acting on DNA
K	0009410	biological_process	response to xenobiotic stimulus
K	0009636	biological_process	response to toxic substance
K	0010165	biological_process	response to X-ray
K	0010569	biological_process	regulation of double-strand break repair via homologous recombination
K	0010833	biological_process	telomere maintenance via telomere lengthening
K	0016605	cellular_component	PML body
K	0017116	molecular_function	single-stranded DNA helicase activity
K	0019899	molecular_function	enzyme binding
K	0031297	biological_process	replication fork processing
K	0032200	biological_process	telomere organization
K	0032991	cellular_component	protein-containing complex
K	0035861	cellular_component	site of double-strand break
K	0036297	biological_process	interstrand cross-link repair
K	0042148	biological_process	DNA strand invasion
K	0042802	molecular_function	identical protein binding
K	0048471	cellular_component	perinuclear region of cytoplasm
K	0051321	biological_process	meiotic cell cycle
K	0070182	molecular_function	DNA polymerase binding
K	0070192	biological_process	chromosome organization involved in meiotic cell cycle
K	0071312	biological_process	cellular response to alkaloid
K	0071479	biological_process	cellular response to ionizing radiation
K	0071480	biological_process	cellular response to gamma radiation
K	0072711	biological_process	cellular response to hydroxyurea
K	0072719	biological_process	cellular response to cisplatin
K	0072757	biological_process	cellular response to camptothecin
K	0099182	cellular_component	presynaptic intermediate filament cytoskeleton
K	0140664	molecular_function	ATP-dependent DNA damage sensor activity
K	1904631	biological_process	response to glucoside
K	1990414	biological_process	replication-born double-strand break repair via sister chromatid exchange
K	1990426	biological_process	mitotic recombination-dependent replication fork processing
K	1990918	biological_process	double-strand break repair involved in meiotic recombination
K	2000001	biological_process	regulation of DNA damage checkpoint
L	0000150	molecular_function	DNA strand exchange activity
L	0000152	cellular_component	nuclear ubiquitin ligase complex
L	0000166	molecular_function	nucleotide binding
L	0000228	cellular_component	nuclear chromosome
L	0000722	biological_process	telomere maintenance via recombination
L	0000724	biological_process	double-strand break repair via homologous recombination
L	0000730	biological_process	DNA recombinase assembly
L	0000781	cellular_component	chromosome, telomeric region
L	0000785	cellular_component	chromatin
L	0000793	cellular_component	condensed chromosome
L	0000794	cellular_component	condensed nuclear chromosome
L	0000800	cellular_component	lateral element
L	0001673	cellular_component	male germ cell nucleus
L	0003677	molecular_function	DNA binding
L	0003682	molecular_function	chromatin binding
L	0003690	molecular_function	double-stranded DNA binding
L	0003697	molecular_function	single-stranded DNA binding
L	0005515	molecular_function	protein binding
L	0005524	molecular_function	ATP binding
L	0005634	cellular_component	nucleus
L	0005654	cellular_component	nucleoplasm
L	0005694	cellular_component	chromosome
L	0005730	cellular_component	nucleolus
L	0005737	cellular_component	cytoplasm
L	0005739	cellular_component	mitochondrion
L	0005759	cellular_component	mitochondrial matrix
L	0005813	cellular_component	centrosome
L	0005829	cellular_component	cytosol
L	0005856	cellular_component	cytoskeleton
L	0006259	biological_process	DNA metabolic process
L	0006281	biological_process	DNA repair
L	0006310	biological_process	DNA recombination
L	0006312	biological_process	mitotic recombination
L	0006974	biological_process	DNA damage response
L	0007127	biological_process	meiosis I
L	0007131	biological_process	reciprocal meiotic recombination
L	0008094	molecular_function	ATP-dependent activity, acting on DNA
L	0009410	biological_process	response to xenobiotic stimulus
L	0009636	biological_process	response to toxic substance
L	0010165	biological_process	response to X-ray
L	0010569	biological_process	regulation of double-strand break repair via homologous recombination
L	0010833	biological_process	telomere maintenance via telomere lengthening
L	0016605	cellular_component	PML body
L	0017116	molecular_function	single-stranded DNA helicase activity
L	0019899	molecular_function	enzyme binding
L	0031297	biological_process	replication fork processing
L	0032200	biological_process	telomere organization
L	0032991	cellular_component	protein-containing complex
L	0035861	cellular_component	site of double-strand break
L	0036297	biological_process	interstrand cross-link repair
L	0042148	biological_process	DNA strand invasion
L	0042802	molecular_function	identical protein binding
L	0048471	cellular_component	perinuclear region of cytoplasm
L	0051321	biological_process	meiotic cell cycle
L	0070182	molecular_function	DNA polymerase binding
L	0070192	biological_process	chromosome organization involved in meiotic cell cycle
L	0071312	biological_process	cellular response to alkaloid
L	0071479	biological_process	cellular response to ionizing radiation
L	0071480	biological_process	cellular response to gamma radiation
L	0072711	biological_process	cellular response to hydroxyurea
L	0072719	biological_process	cellular response to cisplatin
L	0072757	biological_process	cellular response to camptothecin
L	0099182	cellular_component	presynaptic intermediate filament cytoskeleton
L	0140664	molecular_function	ATP-dependent DNA damage sensor activity
L	1904631	biological_process	response to glucoside
L	1990414	biological_process	replication-born double-strand break repair via sister chromatid exchange
L	1990426	biological_process	mitotic recombination-dependent replication fork processing
L	1990918	biological_process	double-strand break repair involved in meiotic recombination
L	2000001	biological_process	regulation of DNA damage checkpoint
M	0000150	molecular_function	DNA strand exchange activity
M	0000152	cellular_component	nuclear ubiquitin ligase complex
M	0000166	molecular_function	nucleotide binding
M	0000228	cellular_component	nuclear chromosome
M	0000722	biological_process	telomere maintenance via recombination
M	0000724	biological_process	double-strand break repair via homologous recombination
M	0000730	biological_process	DNA recombinase assembly
M	0000781	cellular_component	chromosome, telomeric region
M	0000785	cellular_component	chromatin
M	0000793	cellular_component	condensed chromosome
M	0000794	cellular_component	condensed nuclear chromosome
M	0000800	cellular_component	lateral element
M	0001673	cellular_component	male germ cell nucleus
M	0003677	molecular_function	DNA binding
M	0003682	molecular_function	chromatin binding
M	0003690	molecular_function	double-stranded DNA binding
M	0003697	molecular_function	single-stranded DNA binding
M	0005515	molecular_function	protein binding
M	0005524	molecular_function	ATP binding
M	0005634	cellular_component	nucleus
M	0005654	cellular_component	nucleoplasm
M	0005694	cellular_component	chromosome
M	0005730	cellular_component	nucleolus
M	0005737	cellular_component	cytoplasm
M	0005739	cellular_component	mitochondrion
M	0005759	cellular_component	mitochondrial matrix
M	0005813	cellular_component	centrosome
M	0005829	cellular_component	cytosol
M	0005856	cellular_component	cytoskeleton
M	0006259	biological_process	DNA metabolic process
M	0006281	biological_process	DNA repair
M	0006310	biological_process	DNA recombination
M	0006312	biological_process	mitotic recombination
M	0006974	biological_process	DNA damage response
M	0007127	biological_process	meiosis I
M	0007131	biological_process	reciprocal meiotic recombination
M	0008094	molecular_function	ATP-dependent activity, acting on DNA
M	0009410	biological_process	response to xenobiotic stimulus
M	0009636	biological_process	response to toxic substance
M	0010165	biological_process	response to X-ray
M	0010569	biological_process	regulation of double-strand break repair via homologous recombination
M	0010833	biological_process	telomere maintenance via telomere lengthening
M	0016605	cellular_component	PML body
M	0017116	molecular_function	single-stranded DNA helicase activity
M	0019899	molecular_function	enzyme binding
M	0031297	biological_process	replication fork processing
M	0032200	biological_process	telomere organization
M	0032991	cellular_component	protein-containing complex
M	0035861	cellular_component	site of double-strand break
M	0036297	biological_process	interstrand cross-link repair
M	0042148	biological_process	DNA strand invasion
M	0042802	molecular_function	identical protein binding
M	0048471	cellular_component	perinuclear region of cytoplasm
M	0051321	biological_process	meiotic cell cycle
M	0070182	molecular_function	DNA polymerase binding
M	0070192	biological_process	chromosome organization involved in meiotic cell cycle
M	0071312	biological_process	cellular response to alkaloid
M	0071479	biological_process	cellular response to ionizing radiation
M	0071480	biological_process	cellular response to gamma radiation
M	0072711	biological_process	cellular response to hydroxyurea
M	0072719	biological_process	cellular response to cisplatin
M	0072757	biological_process	cellular response to camptothecin
M	0099182	cellular_component	presynaptic intermediate filament cytoskeleton
M	0140664	molecular_function	ATP-dependent DNA damage sensor activity
M	1904631	biological_process	response to glucoside
M	1990414	biological_process	replication-born double-strand break repair via sister chromatid exchange
M	1990426	biological_process	mitotic recombination-dependent replication fork processing
M	1990918	biological_process	double-strand break repair involved in meiotic recombination
M	2000001	biological_process	regulation of DNA damage checkpoint
N	0000150	molecular_function	DNA strand exchange activity
N	0000152	cellular_component	nuclear ubiquitin ligase complex
N	0000166	molecular_function	nucleotide binding
N	0000228	cellular_component	nuclear chromosome
N	0000722	biological_process	telomere maintenance via recombination
N	0000724	biological_process	double-strand break repair via homologous recombination
N	0000730	biological_process	DNA recombinase assembly
N	0000781	cellular_component	chromosome, telomeric region
N	0000785	cellular_component	chromatin
N	0000793	cellular_component	condensed chromosome
N	0000794	cellular_component	condensed nuclear chromosome
N	0000800	cellular_component	lateral element
N	0001673	cellular_component	male germ cell nucleus
N	0003677	molecular_function	DNA binding
N	0003682	molecular_function	chromatin binding
N	0003690	molecular_function	double-stranded DNA binding
N	0003697	molecular_function	single-stranded DNA binding
N	0005515	molecular_function	protein binding
N	0005524	molecular_function	ATP binding
N	0005634	cellular_component	nucleus
N	0005654	cellular_component	nucleoplasm
N	0005694	cellular_component	chromosome
N	0005730	cellular_component	nucleolus
N	0005737	cellular_component	cytoplasm
N	0005739	cellular_component	mitochondrion
N	0005759	cellular_component	mitochondrial matrix
N	0005813	cellular_component	centrosome
N	0005829	cellular_component	cytosol
N	0005856	cellular_component	cytoskeleton
N	0006259	biological_process	DNA metabolic process
N	0006281	biological_process	DNA repair
N	0006310	biological_process	DNA recombination
N	0006312	biological_process	mitotic recombination
N	0006974	biological_process	DNA damage response
N	0007127	biological_process	meiosis I
N	0007131	biological_process	reciprocal meiotic recombination
N	0008094	molecular_function	ATP-dependent activity, acting on DNA
N	0009410	biological_process	response to xenobiotic stimulus
N	0009636	biological_process	response to toxic substance
N	0010165	biological_process	response to X-ray
N	0010569	biological_process	regulation of double-strand break repair via homologous recombination
N	0010833	biological_process	telomere maintenance via telomere lengthening
N	0016605	cellular_component	PML body
N	0017116	molecular_function	single-stranded DNA helicase activity
N	0019899	molecular_function	enzyme binding
N	0031297	biological_process	replication fork processing
N	0032200	biological_process	telomere organization
N	0032991	cellular_component	protein-containing complex
N	0035861	cellular_component	site of double-strand break
N	0036297	biological_process	interstrand cross-link repair
N	0042148	biological_process	DNA strand invasion
N	0042802	molecular_function	identical protein binding
N	0048471	cellular_component	perinuclear region of cytoplasm
N	0051321	biological_process	meiotic cell cycle
N	0070182	molecular_function	DNA polymerase binding
N	0070192	biological_process	chromosome organization involved in meiotic cell cycle
N	0071312	biological_process	cellular response to alkaloid
N	0071479	biological_process	cellular response to ionizing radiation
N	0071480	biological_process	cellular response to gamma radiation
N	0072711	biological_process	cellular response to hydroxyurea
N	0072719	biological_process	cellular response to cisplatin
N	0072757	biological_process	cellular response to camptothecin
N	0099182	cellular_component	presynaptic intermediate filament cytoskeleton
N	0140664	molecular_function	ATP-dependent DNA damage sensor activity
N	1904631	biological_process	response to glucoside
N	1990414	biological_process	replication-born double-strand break repair via sister chromatid exchange
N	1990426	biological_process	mitotic recombination-dependent replication fork processing
N	1990918	biological_process	double-strand break repair involved in meiotic recombination
N	2000001	biological_process	regulation of DNA damage checkpoint

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue MG A 401

Chain	Residue
A	THR134
A	THR165
A	ASP222
A	ATP402

site_id	AC2
Number of Residues	15
Details	binding site for residue ATP A 402

Chain	Residue
A	THR134
A	GLN135
A	ARG170
A	GLN268
A	ARG310
A	ILE329
A	ASN330
A	ALA331
A	MG401
G	PRO318
A	PHE129
A	ARG130
A	THR131
A	GLY132
A	LYS133

site_id	AC3
Number of Residues	4
Details	binding site for residue MG B 401

Chain	Residue
B	THR134
B	THR165
B	ASP222
B	ATP402

site_id	AC4
Number of Residues	18
Details	binding site for residue ATP B 402

Chain	Residue
A	SER317
A	CYS319
A	LEU320
A	PRO321
A	GLU322
B	PHE129
B	ARG130
B	GLY132
B	LYS133
B	THR134
B	GLN135
B	ARG170
B	GLN268
B	ARG310
B	ILE329
B	ASN330
B	ALA331
B	MG401

site_id	AC5
Number of Residues	4
Details	binding site for residue MG C 401

Chain	Residue
C	THR134
C	THR165
C	ASP222
C	ATP402

site_id	AC6
Number of Residues	16
Details	binding site for residue ATP C 402

Chain	Residue
B	SER317
B	CYS319
B	LEU320
B	PRO321
B	GLU322
C	ARG130
C	GLY132
C	LYS133
C	THR134
C	GLN135
C	ARG170
C	GLN268
C	ARG310
C	ILE329
C	ASN330
C	MG401

site_id	AC7
Number of Residues	3
Details	binding site for residue MG D 401

Chain	Residue
D	THR134
D	ASP222
D	ATP402

site_id	AC8
Number of Residues	15
Details	binding site for residue ATP D 402

Chain	Residue
C	SER317
C	LEU320
C	PRO321
C	GLU322
D	PHE129
D	ARG130
D	GLY132
D	LYS133
D	THR134
D	GLN135
D	ARG170
D	GLN268
D	ARG310
D	ILE329
D	MG401

site_id	AC9
Number of Residues	3
Details	binding site for residue MG E 401

Chain	Residue
E	THR134
E	THR165
E	ATP402

site_id	AD1
Number of Residues	14
Details	binding site for residue ATP E 402

Chain	Residue
D	SER317
D	CYS319
D	LEU320
D	PRO321
D	GLU322
E	ARG130
E	GLY132
E	LYS133
E	THR134
E	GLN135
E	ARG170
E	GLN268
E	ARG310
E	MG401

site_id	AD2
Number of Residues	4
Details	binding site for residue MG F 401

Chain	Residue
F	ATP402
F	THR134
F	THR165
F	ASP222

site_id	AD3
Number of Residues	16
Details	binding site for residue ATP F 402

Chain	Residue
E	SER317
E	CYS319
E	LEU320
E	PRO321
E	GLU322
F	PHE129
F	ARG130
F	GLY132
F	LYS133
F	THR134
F	GLN135
F	ARG170
F	GLN268
F	ARG310
F	ILE329
F	MG401

site_id	AD4
Number of Residues	4
Details	binding site for residue MG G 401

Chain	Residue
G	THR134
G	THR165
G	ASP222
G	ATP402

site_id	AD5
Number of Residues	16
Details	binding site for residue ATP G 402

Chain	Residue
F	SER317
F	CYS319
F	LEU320
F	PRO321
F	GLU322
G	PHE129
G	ARG130
G	GLY132
G	LYS133
G	THR134
G	GLN135
G	ARG170
G	GLN268
G	ARG310
G	ILE329
G	MG401

site_id	AD6
Number of Residues	3
Details	binding site for residue MG H 401

Chain	Residue
H	THR134
H	THR165
H	ATP402

site_id	AD7
Number of Residues	13
Details	binding site for residue ATP H 402

Chain	Residue
H	PHE129
H	ARG130
H	THR131
H	GLY132
H	LYS133
H	THR134
H	GLN135
H	ARG170
H	GLN268
H	ARG310
H	ILE329
H	MG401
N	SER317

site_id	AD8
Number of Residues	4
Details	binding site for residue MG I 401

Chain	Residue
I	THR134
I	THR165
I	ASP222
I	ATP402

site_id	AD9
Number of Residues	14
Details	binding site for residue ATP I 402

Chain	Residue
H	SER317
H	CYS319
H	LEU320
H	PRO321
H	GLU322
I	ARG130
I	GLY132
I	LYS133
I	THR134
I	GLN135
I	ARG170
I	GLN268
I	ARG310
I	MG401

site_id	AE1
Number of Residues	3
Details	binding site for residue MG J 401

Chain	Residue
J	THR134
J	THR165
J	ATP402

site_id	AE2
Number of Residues	18
Details	binding site for residue ATP J 402

Chain	Residue
I	TYR315
I	SER317
I	CYS319
I	LEU320
I	PRO321
I	GLU322
J	ARG130
J	THR131
J	GLY132
J	LYS133
J	THR134
J	GLN135
J	ARG170
J	GLN268
J	ARG310
J	ASN330
J	ALA331
J	MG401

site_id	AE3
Number of Residues	3
Details	binding site for residue MG K 401

Chain	Residue
K	THR134
K	THR165
K	ATP402

site_id	AE4
Number of Residues	15
Details	binding site for residue ATP K 402

Chain	Residue
J	SER317
J	LEU320
J	PRO321
J	GLU322
K	PHE129
K	ARG130
K	GLY132
K	LYS133
K	THR134
K	GLN135
K	ARG170
K	GLN268
K	ARG310
K	ILE329
K	MG401

site_id	AE5
Number of Residues	4
Details	binding site for residue MG L 401

Chain	Residue
L	THR134
L	THR165
L	ASP222
L	ATP402

site_id	AE6
Number of Residues	16
Details	binding site for residue ATP L 402

Chain	Residue
K	CYS319
K	LEU320
K	PRO321
K	GLU322
L	ARG130
L	GLY132
L	LYS133
L	THR134
L	GLN135
L	ARG170
L	GLN268
L	ARG310
L	ILE329
L	ASN330
L	ALA331
L	MG401

site_id	AE7
Number of Residues	4
Details	binding site for residue MG M 401

Chain	Residue
M	THR134
M	THR165
M	ASP222
M	ATP402

site_id	AE8
Number of Residues	14
Details	binding site for residue ATP M 402

Chain	Residue
L	SER317
L	CYS319
L	LEU320
L	PRO321
L	GLU322
M	ARG130
M	GLY132
M	LYS133
M	THR134
M	GLN135
M	ARG170
M	GLN268
M	ARG310
M	MG401

site_id	AE9
Number of Residues	4
Details	binding site for residue MG N 401

Chain	Residue
N	THR134
N	THR165
N	ASP222
N	ATP402

site_id	AF1
Number of Residues	16
Details	binding site for residue ATP N 402

Chain	Residue
M	SER317
M	CYS319
M	LEU320
M	PRO321
M	GLU322
N	ARG130
N	GLY132
N	LYS133
N	THR134
N	GLN135
N	ARG170
N	GLN268
N	ARG310
N	ILE329
N	ASN330
N	MG401

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	406
Details	Domain: {"description":"HhH"}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	1022
Details	Region: {"description":"Interaction with PALB2"}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	210
Details	Motif: {"description":"Nuclear export signal; masked by the interaction with BRCA2","evidences":[{"source":"PubMed","id":"24013206","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	98
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	14
Details	Modified residue: {"description":"Phosphotyrosine; by ABL1","evidences":[{"source":"PubMed","id":"9461559","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	14
Details	Modified residue: {"description":"Phosphothreonine; by CHEK1","evidences":[{"source":"PubMed","id":"15665856","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	42
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"23393192","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)