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5NU1

Structural states of RORgt: X-ray elucidation of molecular mechanisms and binding interactions for natural and synthetic compounds

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0004879molecular_functionnuclear receptor activity
A0005634cellular_componentnucleus
A0006355biological_processregulation of DNA-templated transcription
B0003677molecular_functionDNA binding
B0004879molecular_functionnuclear receptor activity
B0005634cellular_componentnucleus
B0006355biological_processregulation of DNA-templated transcription
Functional Information from PDB Data
site_idAC1
Number of Residues18
Detailsbinding site for residue 8YB A 601
ChainResidue
ACYS285
AALA368
AVAL376
APHE377
APHE378
APHE388
AILE400
APHE401
ASER404
AHOH725
AGLN286
ALEU287
ACYS320
AHIS323
ALEU324
AARG364
AMET365
AARG367

site_idAC2
Number of Residues18
Detailsbinding site for residue 8YB B 601
ChainResidue
BCYS285
BGLN286
BLEU287
BCYS320
BHIS323
BLEU324
BARG364
BMET365
BARG367
BALA368
BVAL376
BPHE377
BPHE378
BPHE388
BILE400
BPHE401
BSER404
BHOH709

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733
ChainResidueDetails
QLYS508
PLYS508

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PDB entries from 2024-06-12

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