Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0004879 | molecular_function | nuclear receptor activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0003677 | molecular_function | DNA binding |
| B | 0004879 | molecular_function | nuclear receptor activity |
| B | 0005634 | cellular_component | nucleus |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| C | 0003677 | molecular_function | DNA binding |
| C | 0004879 | molecular_function | nuclear receptor activity |
| C | 0005634 | cellular_component | nucleus |
| C | 0006355 | biological_process | regulation of DNA-templated transcription |
| D | 0003677 | molecular_function | DNA binding |
| D | 0004879 | molecular_function | nuclear receptor activity |
| D | 0005634 | cellular_component | nucleus |
| D | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | binding site for residue 98N A 601 |
| Chain | Residue |
| A | CYS285 |
| A | ALA368 |
| A | PHE377 |
| A | LEU391 |
| A | CYS393 |
| A | LEU396 |
| A | ILE400 |
| A | HIS479 |
| A | ARG482 |
| A | HOH770 |
| A | HOH815 |
| A | GLN286 |
| A | LEU287 |
| A | TRP317 |
| A | CYS320 |
| A | HIS323 |
| A | ARG364 |
| A | MET365 |
| A | ARG367 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | binding site for residue 98N B 601 |
| Chain | Residue |
| B | CYS285 |
| B | GLN286 |
| B | LEU287 |
| B | HIS323 |
| B | ARG364 |
| B | MET365 |
| B | ARG367 |
| B | ALA368 |
| B | PHE377 |
| B | PHE378 |
| B | PHE388 |
| B | LEU391 |
| B | CYS393 |
| B | LEU396 |
| B | HIS479 |
| B | HOH770 |
| B | HOH795 |
| site_id | AC3 |
| Number of Residues | 17 |
| Details | binding site for residue 98N C 601 |
| Chain | Residue |
| C | CYS285 |
| C | GLN286 |
| C | LEU287 |
| C | TRP317 |
| C | HIS323 |
| C | ARG364 |
| C | MET365 |
| C | ARG367 |
| C | ALA368 |
| C | PHE377 |
| C | LEU391 |
| C | CYS393 |
| C | LEU396 |
| C | HIS479 |
| C | ARG482 |
| C | HOH763 |
| C | HOH849 |
| site_id | AC4 |
| Number of Residues | 18 |
| Details | binding site for residue 98N D 601 |
| Chain | Residue |
| D | CYS285 |
| D | GLN286 |
| D | LEU287 |
| D | TRP317 |
| D | CYS320 |
| D | HIS323 |
| D | ARG364 |
| D | MET365 |
| D | ARG367 |
| D | ALA368 |
| D | PHE377 |
| D | LEU391 |
| D | CYS393 |
| D | LEU396 |
| D | HIS479 |
| D | ARG482 |
| D | HOH765 |
| D | HOH808 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 956 |
| Details | Domain: {"description":"NR LBD","evidences":[{"source":"PROSITE-ProRule","id":"PRU01189","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | Motif: {"description":"AF-2"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 16 |
| Details | Motif: {"description":"LXXLL motif 6"} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]} |
