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5NPV

Structure of human ATG5-ATG16L1(ATG5BD) complex (I4)

Functional Information from GO Data
ChainGOidnamespacecontents
A0000045biological_processautophagosome assembly
A0000422biological_processautophagy of mitochondrion
A0000423biological_processmitophagy
A0001974biological_processblood vessel remodeling
A0002376biological_processimmune system process
A0002718biological_processregulation of cytokine production involved in immune response
A0005515molecular_functionprotein binding
A0005737cellular_componentcytoplasm
A0005776cellular_componentautophagosome
A0005829cellular_componentcytosol
A0005930cellular_componentaxoneme
A0006325biological_processchromatin organization
A0006914biological_processautophagy
A0006915biological_processapoptotic process
A0006995biological_processcellular response to nitrogen starvation
A0009267biological_processcellular response to starvation
A0009410biological_processresponse to xenobiotic stimulus
A0009620biological_processresponse to fungus
A0010040biological_processresponse to iron(II) ion
A0010659biological_processcardiac muscle cell apoptotic process
A0010667biological_processnegative regulation of cardiac muscle cell apoptotic process
A0016020cellular_componentmembrane
A0016236biological_processmacroautophagy
A0016567biological_processprotein ubiquitination
A0019776molecular_functionAtg8-family ligase activity
A0019883biological_processantigen processing and presentation of endogenous antigen
A0030424cellular_componentaxon
A0030670cellular_componentphagocytic vesicle membrane
A0031397biological_processnegative regulation of protein ubiquitination
A0032480biological_processnegative regulation of type I interferon production
A0032991cellular_componentprotein-containing complex
A0034045cellular_componentphagophore assembly site membrane
A0034274cellular_componentAtg12-Atg5-Atg16 complex
A0034727biological_processpiecemeal microautophagy of the nucleus
A0035973biological_processaggrephagy
A0039689biological_processnegative stranded viral RNA replication
A0042311biological_processvasodilation
A0043066biological_processnegative regulation of apoptotic process
A0043687biological_processpost-translational protein modification
A0044233cellular_componentmitochondria-associated endoplasmic reticulum membrane contact site
A0045060biological_processnegative thymic T cell selection
A0045824biological_processnegative regulation of innate immune response
A0048840biological_processotolith development
A0050687biological_processnegative regulation of defense response to virus
A0050765biological_processnegative regulation of phagocytosis
A0051279biological_processregulation of release of sequestered calcium ion into cytosol
A0051649biological_processestablishment of localization in cell
A0055015biological_processventricular cardiac muscle cell development
A0060047biological_processheart contraction
A0061684biological_processchaperone-mediated autophagy
A0061908cellular_componentphagophore
A0062029biological_processpositive regulation of stress granule assembly
A0070254biological_processmucus secretion
A0070257biological_processpositive regulation of mucus secretion
A0071500biological_processcellular response to nitrosative stress
A1901096biological_processregulation of autophagosome maturation
A1902017biological_processregulation of cilium assembly
A1902617biological_processresponse to fluoride
A1904093biological_processnegative regulation of autophagic cell death
A1904973biological_processpositive regulation of viral translation
A1990234cellular_componenttransferase complex
A2000377biological_processregulation of reactive oxygen species metabolic process
A2000378biological_processnegative regulation of reactive oxygen species metabolic process
B0000045biological_processautophagosome assembly
C0000045biological_processautophagosome assembly
C0000422biological_processautophagy of mitochondrion
C0000423biological_processmitophagy
C0001974biological_processblood vessel remodeling
C0002376biological_processimmune system process
C0002718biological_processregulation of cytokine production involved in immune response
C0005515molecular_functionprotein binding
C0005737cellular_componentcytoplasm
C0005776cellular_componentautophagosome
C0005829cellular_componentcytosol
C0005930cellular_componentaxoneme
C0006325biological_processchromatin organization
C0006914biological_processautophagy
C0006915biological_processapoptotic process
C0006995biological_processcellular response to nitrogen starvation
C0009267biological_processcellular response to starvation
C0009410biological_processresponse to xenobiotic stimulus
C0009620biological_processresponse to fungus
C0010040biological_processresponse to iron(II) ion
C0010659biological_processcardiac muscle cell apoptotic process
C0010667biological_processnegative regulation of cardiac muscle cell apoptotic process
C0016020cellular_componentmembrane
C0016236biological_processmacroautophagy
C0016567biological_processprotein ubiquitination
C0019776molecular_functionAtg8-family ligase activity
C0019883biological_processantigen processing and presentation of endogenous antigen
C0030424cellular_componentaxon
C0030670cellular_componentphagocytic vesicle membrane
C0031397biological_processnegative regulation of protein ubiquitination
C0032480biological_processnegative regulation of type I interferon production
C0032991cellular_componentprotein-containing complex
C0034045cellular_componentphagophore assembly site membrane
C0034274cellular_componentAtg12-Atg5-Atg16 complex
C0034727biological_processpiecemeal microautophagy of the nucleus
C0035973biological_processaggrephagy
C0039689biological_processnegative stranded viral RNA replication
C0042311biological_processvasodilation
C0043066biological_processnegative regulation of apoptotic process
C0043687biological_processpost-translational protein modification
C0044233cellular_componentmitochondria-associated endoplasmic reticulum membrane contact site
C0045060biological_processnegative thymic T cell selection
C0045824biological_processnegative regulation of innate immune response
C0048840biological_processotolith development
C0050687biological_processnegative regulation of defense response to virus
C0050765biological_processnegative regulation of phagocytosis
C0051279biological_processregulation of release of sequestered calcium ion into cytosol
C0051649biological_processestablishment of localization in cell
C0055015biological_processventricular cardiac muscle cell development
C0060047biological_processheart contraction
C0061684biological_processchaperone-mediated autophagy
C0061908cellular_componentphagophore
C0062029biological_processpositive regulation of stress granule assembly
C0070254biological_processmucus secretion
C0070257biological_processpositive regulation of mucus secretion
C0071500biological_processcellular response to nitrosative stress
C1901096biological_processregulation of autophagosome maturation
C1902017biological_processregulation of cilium assembly
C1902617biological_processresponse to fluoride
C1904093biological_processnegative regulation of autophagic cell death
C1904973biological_processpositive regulation of viral translation
C1990234cellular_componenttransferase complex
C2000377biological_processregulation of reactive oxygen species metabolic process
C2000378biological_processnegative regulation of reactive oxygen species metabolic process
D0000045biological_processautophagosome assembly
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsMOD_RES: Phosphoserine; by CK2 => ECO:0000269|PubMed:26083323
ChainResidueDetails
BSER139
DSER139

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231
ChainResidueDetails
BSER269
DSER269
CLYS130

site_idSWS_FT_FI3
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163
ChainResidueDetails
BSER287
DSER287

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PDB entries from 2024-07-10

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