Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0016831 | molecular_function | carboxy-lyase activity |
| A | 0030976 | molecular_function | thiamine pyrophosphate binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0016831 | molecular_function | carboxy-lyase activity |
| B | 0030976 | molecular_function | thiamine pyrophosphate binding |
| C | 0000287 | molecular_function | magnesium ion binding |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0016831 | molecular_function | carboxy-lyase activity |
| C | 0030976 | molecular_function | thiamine pyrophosphate binding |
| D | 0000287 | molecular_function | magnesium ion binding |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0016831 | molecular_function | carboxy-lyase activity |
| D | 0030976 | molecular_function | thiamine pyrophosphate binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 601 |
| Chain | Residue |
| A | ASP441 |
| A | ILE466 |
| A | ASN468 |
| A | GLY470 |
| A | TPP602 |
| site_id | AC2 |
| Number of Residues | 20 |
| Details | binding site for residue TPP A 602 |
| Chain | Residue |
| A | ASP391 |
| A | GLY414 |
| A | HIS415 |
| A | ILE416 |
| A | GLY440 |
| A | ASP441 |
| A | GLY442 |
| A | SER443 |
| A | LEU446 |
| A | ASN468 |
| A | GLY470 |
| A | TYR471 |
| A | THR472 |
| A | ILE473 |
| A | GLU474 |
| A | MG601 |
| A | ALA25 |
| A | GLU50 |
| A | VAL75 |
| A | HIS114 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue MG B 601 |
| Chain | Residue |
| B | ASP441 |
| B | ASN468 |
| B | GLY470 |
| B | TPP602 |
| site_id | AC4 |
| Number of Residues | 22 |
| Details | binding site for residue TPP B 602 |
| Chain | Residue |
| B | ALA25 |
| B | GLY26 |
| B | GLU50 |
| B | VAL75 |
| B | HIS114 |
| B | THR389 |
| B | ASP391 |
| B | GLY414 |
| B | HIS415 |
| B | ILE416 |
| B | GLY440 |
| B | ASP441 |
| B | GLY442 |
| B | SER443 |
| B | LEU446 |
| B | ASN468 |
| B | GLY470 |
| B | TYR471 |
| B | THR472 |
| B | ILE473 |
| B | GLU474 |
| B | MG601 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue MG C 601 |
| Chain | Residue |
| C | ASP441 |
| C | ASN468 |
| C | GLY470 |
| C | THR472 |
| C | TPP602 |
| site_id | AC6 |
| Number of Residues | 22 |
| Details | binding site for residue TPP C 602 |
| Chain | Residue |
| C | ALA25 |
| C | GLU50 |
| C | VAL75 |
| C | HIS114 |
| C | THR389 |
| C | GLY390 |
| C | ASP391 |
| C | GLY414 |
| C | HIS415 |
| C | ILE416 |
| C | GLY440 |
| C | ASP441 |
| C | GLY442 |
| C | SER443 |
| C | LEU446 |
| C | ASN468 |
| C | GLY470 |
| C | TYR471 |
| C | THR472 |
| C | ILE473 |
| C | GLU474 |
| C | MG601 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue PEG C 603 |
| Chain | Residue |
| C | HIS150 |
| C | ARG153 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue MG D 601 |
| Chain | Residue |
| D | ASP441 |
| D | ASN468 |
| D | GLY470 |
| D | THR472 |
| D | TPP602 |
| site_id | AC9 |
| Number of Residues | 23 |
| Details | binding site for residue TPP D 602 |
| Chain | Residue |
| D | SER443 |
| D | LEU446 |
| D | ASN468 |
| D | GLY470 |
| D | TYR471 |
| D | THR472 |
| D | ILE473 |
| D | GLU474 |
| D | MG601 |
| D | ALA25 |
| D | GLY26 |
| D | GLU50 |
| D | VAL75 |
| D | HIS114 |
| D | GLY390 |
| D | ASP391 |
| D | SER392 |
| D | GLY414 |
| D | HIS415 |
| D | ILE416 |
| D | GLY440 |
| D | ASP441 |
| D | GLY442 |
Functional Information from PROSITE/UniProt
| site_id | PS00187 |
| Number of Residues | 20 |
| Details | TPP_ENZYMES Thiamine pyrophosphate enzymes signature. FGyavaePerrnVlMvGDGS |
| Chain | Residue | Details |
| A | PHE424-SER443 | |
