5NPF

Crystal structure of txGH116 (beta-glucosidase from Thermoanaerobacterium xylolyticum) in complex with beta Cyclophellitol Cyclosulfate probe ME594

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004348	molecular_function	glucosylceramidase activity
A	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
A	0005975	biological_process	carbohydrate metabolic process
A	0006680	biological_process	glucosylceramide catabolic process
A	0008422	molecular_function	beta-glucosidase activity
A	0016020	cellular_component	membrane
A	0016787	molecular_function	hydrolase activity
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue EDO A 901

Chain	Residue
A	THR45
A	GLU50
A	TYR764
A	LYS766

---

site_id	AC2
Number of Residues	5
Details	binding site for residue EDO A 902

Chain	Residue
A	GLY362
A	LYS363
A	ASN364
A	HOH1020
A	HOH1122

---

site_id	AC3
Number of Residues	7
Details	binding site for residue EDO A 903

Chain	Residue
A	VAL124
A	GLN126
A	LYS142
A	PRO146
A	ASN165
A	ASP167
A	HOH1348

---

site_id	AC4
Number of Residues	7
Details	binding site for residue EDO A 904

Chain	Residue
A	TRP595
A	SER596
A	PHE654
A	SER658
A	HIS660
A	ASP722
A	SER724

---

site_id	AC5
Number of Residues	4
Details	binding site for residue EDO A 905

Chain	Residue
A	LYS397
A	LYS708
A	TYR757
A	LYS761

---

site_id	AC6
Number of Residues	4
Details	binding site for residue EDO A 906

Chain	Residue
A	GLU245
A	ILE277
A	TYR279
A	ASN304

---

site_id	AC7
Number of Residues	6
Details	binding site for residue EDO A 907

Chain	Residue
A	PHE443
A	ASP444
A	TYR513
A	HOH1051
A	HOH1296
A	HOH1339

---

site_id	AC8
Number of Residues	7
Details	binding site for residue EDO A 908

Chain	Residue
A	MET218
A	GLY220
A	PHE221
A	PHE222
A	TRP261
A	TYR265
A	LEU342

---

site_id	AC9
Number of Residues	4
Details	binding site for residue EDO A 909

Chain	Residue
A	ARG432
A	THR433
A	ASN434
A	HOH1285

---

site_id	AD1
Number of Residues	7
Details	binding site for residue EDO A 910

Chain	Residue
A	GLN225
A	LYS235
A	GLU264
A	LYS366
A	SER368
A	PHE369
A	HOH1355

---

site_id	AD2
Number of Residues	3
Details	binding site for residue EDO A 911

Chain	Residue
A	TRP647
A	HIS688
A	HOH1166

---

site_id	AD3
Number of Residues	4
Details	binding site for residue EDO A 912

Chain	Residue
A	ASP676
A	TYR745
A	ARG746
A	HOH1031

---

site_id	AD4
Number of Residues	4
Details	binding site for residue EDO A 913

Chain	Residue
A	ILE518
A	LYS519
A	ILE520
A	HOH1067

---

site_id	AD5
Number of Residues	7
Details	binding site for residue CA A 914

Chain	Residue
A	ASP575
A	ASP577
A	ASP579
A	ILE581
A	ASP583
A	HOH1047
A	HOH1077

---

site_id	AD6
Number of Residues	14
Details	binding site for residue 945 A 915

Chain	Residue
A	GLU441
A	TYR445
A	THR450
A	ASP452
A	HIS507
A	TYR523
A	TRP531
A	THR591
A	ASP593
A	GLU777
A	ARG786
A	TYR790
A	ARG792
A	HOH1337

---