5NKM
SMG8-SMG9 complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000184 | biological_process | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |
| B | 0000184 | biological_process | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |
| C | 0000184 | biological_process | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |
| D | 0000184 | biological_process | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |
| E | 0000184 | biological_process | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |
| F | 0000184 | biological_process | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 501 |
| Chain | Residue |
| A | ILE232 |
| A | ASP233 |
| A | SER238 |
| A | CYS240 |
| A | GLN241 |
| A | LEU242 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 502 |
| Chain | Residue |
| A | LEU228 |
| B | ASP172 |
| B | ASP173 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 501 |
| Chain | Residue |
| C | GLU106 |
| C | GLU135 |
| C | PHE139 |
| C | LYS142 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue EDO C 502 |
| Chain | Residue |
| B | HOH401 |
| C | LYS21 |
| C | VAL166 |
| C | GLU305 |
| C | ILE306 |
| C | SER307 |
| C | ASN310 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue TRS C 503 |
| Chain | Residue |
| C | ASP31 |
| C | ASP81 |
| D | TYR202 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue PEG C 504 |
| Chain | Residue |
| C | TYR44 |
| C | ASP70 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue PEG C 505 |
| Chain | Residue |
| C | LYS141 |
| C | ASN144 |
| C | ILE148 |
| C | ASP230 |
| C | SER237 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue EDO D 401 |
| Chain | Residue |
| C | ILE342 |
| C | GLN343 |
| C | HIS346 |
| C | VAL398 |
| C | GLY400 |
| D | GLN215 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO D 402 |
| Chain | Residue |
| D | ALA185 |
| D | LEU188 |
| D | TYR189 |
| D | GLU214 |
| D | ARG217 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO E 501 |
| Chain | Residue |
| E | LYS23 |
| E | ASP70 |
| E | GLU296 |
| E | PHE299 |
| site_id | AD2 |
| Number of Residues | 1 |
| Details | binding site for residue EDO E 502 |
| Chain | Residue |
| E | ALA160 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO E 503 |
| Chain | Residue |
| E | ARG171 |
| E | LEU173 |
| E | VAL184 |
| E | GLN241 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO E 504 |
| Chain | Residue |
| E | GLU177 |
| E | VAL184 |
| E | GLY235 |
| E | SER238 |
| E | GLN241 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO E 505 |
| Chain | Residue |
| E | GLU305 |
| E | ILE306 |
| E | SER307 |
| E | ASN310 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue TRS E 506 |
| Chain | Residue |
| E | LYS30 |
| E | ASP31 |
| E | ASP81 |
| F | TYR202 |
| F | HOH403 |
