5NKJ

X-ray structure of the N239C mutant of GLIC

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004888	molecular_function	transmembrane signaling receptor activity
A	0005216	molecular_function	monoatomic ion channel activity
A	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
A	0006811	biological_process	monoatomic ion transport
A	0016020	cellular_component	membrane
A	0034220	biological_process	monoatomic ion transmembrane transport
B	0004888	molecular_function	transmembrane signaling receptor activity
B	0005216	molecular_function	monoatomic ion channel activity
B	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
B	0006811	biological_process	monoatomic ion transport
B	0016020	cellular_component	membrane
B	0034220	biological_process	monoatomic ion transmembrane transport
C	0004888	molecular_function	transmembrane signaling receptor activity
C	0005216	molecular_function	monoatomic ion channel activity
C	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
C	0006811	biological_process	monoatomic ion transport
C	0016020	cellular_component	membrane
C	0034220	biological_process	monoatomic ion transmembrane transport
D	0004888	molecular_function	transmembrane signaling receptor activity
D	0005216	molecular_function	monoatomic ion channel activity
D	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
D	0006811	biological_process	monoatomic ion transport
D	0016020	cellular_component	membrane
D	0034220	biological_process	monoatomic ion transmembrane transport
E	0004888	molecular_function	transmembrane signaling receptor activity
E	0005216	molecular_function	monoatomic ion channel activity
E	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
E	0006811	biological_process	monoatomic ion transport
E	0016020	cellular_component	membrane
E	0034220	biological_process	monoatomic ion transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 318

Chain	Residue
A	PHE78
A	ARG85

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site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL B 318

Chain	Residue
B	PHE78
B	ARG85

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site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL C 318

Chain	Residue
C	PHE78
C	ARG85

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site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL D 318

Chain	Residue
D	PHE78
D	ARG85

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site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE LMT E 318

Chain	Residue
B	ILE233
B	ILE240
D	ILE240
A	ILE233

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site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL E 319

Chain	Residue
E	PHE78
E	ARG85

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	990
Details	TOPO_DOM: Periplasmic => ECO:0000255

Chain	Residue	Details
A	GLN2-GLN193
E	ASN245-MET252
A	ASN245-MET252
B	GLN2-GLN193
B	ASN245-MET252
C	GLN2-GLN193
C	ASN245-MET252
D	GLN2-GLN193
D	ASN245-MET252
E	GLN2-GLN193

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site_id	SWS_FT_FI2
Number of Residues	530
Details	TRANSMEM: Helical

Chain	Residue	Details
A	TYR194-PHE216
C	SER220-THR244
C	THR253-VAL281
C	PRO285-PHE317
D	TYR194-PHE216
D	SER220-THR244
D	THR253-VAL281
D	PRO285-PHE317
E	TYR194-PHE216
E	SER220-THR244
E	THR253-VAL281
A	SER220-THR244
E	PRO285-PHE317
A	THR253-VAL281
A	PRO285-PHE317
B	TYR194-PHE216
B	SER220-THR244
B	THR253-VAL281
B	PRO285-PHE317
C	TYR194-PHE216

---

site_id	SWS_FT_FI3
Number of Residues	20
Details	TOPO_DOM: Cytoplasmic => ECO:0000255

Chain	Residue	Details
A	TRP217-THR219
E	GLU282-GLN284
A	GLU282-GLN284
B	TRP217-THR219
B	GLU282-GLN284
C	TRP217-THR219
C	GLU282-GLN284
D	TRP217-THR219
D	GLU282-GLN284
E	TRP217-THR219

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