5NJD

Structure of Interleukin 23 in complex with Briakinumab FAb

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004896	molecular_function	cytokine receptor activity
A	0016020	cellular_component	membrane
B	0005125	molecular_function	cytokine activity
B	0005576	cellular_component	extracellular region
B	0006955	biological_process	immune response
C	0004896	molecular_function	cytokine receptor activity
C	0016020	cellular_component	membrane
D	0005125	molecular_function	cytokine activity
D	0005576	cellular_component	extracellular region
D	0006955	biological_process	immune response
E	0004896	molecular_function	cytokine receptor activity
E	0016020	cellular_component	membrane
F	0005125	molecular_function	cytokine activity
F	0005576	cellular_component	extracellular region
F	0006955	biological_process	immune response
G	0004896	molecular_function	cytokine receptor activity
G	0016020	cellular_component	membrane
H	0005125	molecular_function	cytokine activity
H	0005576	cellular_component	extracellular region
H	0006955	biological_process	immune response
I	0004896	molecular_function	cytokine receptor activity
I	0016020	cellular_component	membrane
J	0005125	molecular_function	cytokine activity
J	0005576	cellular_component	extracellular region
J	0006955	biological_process	immune response
K	0004896	molecular_function	cytokine receptor activity
K	0016020	cellular_component	membrane
L	0005125	molecular_function	cytokine activity
L	0005576	cellular_component	extracellular region
L	0006955	biological_process	immune response

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YSCQVTH

Chain	Residue	Details
M	TYR196-HIS202
N	TYR196-HIS202

---

site_id	PS01354
Number of Residues	43
Details	HEMATOPO_REC_L_F3 Long hematopoietin receptor, soluble alpha chains family signature. IkPDPPknLqlkplknsrq.VevsWeyPdTWstphsyFsLtFcV

Chain	Residue	Details
A	ILE233-VAL275

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	498
Details	Domain: {"description":"Ig-like C2-type"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	6
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"10899108","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	6
Details	Glycosylation: {"description":"C-linked (Man) tryptophan","featureId":"CAR_000187","evidences":[{"source":"PubMed","id":"10207176","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---