5NIS

Neutral trehalase Nth1 from Saccharomyces cerevisiae

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004555	molecular_function	alpha,alpha-trehalase activity
A	0005509	molecular_function	calcium ion binding
A	0005737	cellular_component	cytoplasm
A	0005975	biological_process	carbohydrate metabolic process
A	0005991	biological_process	trehalose metabolic process
A	0005993	biological_process	trehalose catabolic process

Functional Information from PROSITE/UniProt

site_id	PS00927
Number of Residues	14
Details	TREHALASE_1 Trehalase signature 1. PGGRFnElYgWDsY

Chain	Residue	Details
A	PRO299-TYR312

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site_id	PS00928
Number of Residues	10
Details	TREHALASE_2 Trehalase signature 2. QWDyPfGWAP

Chain	Residue	Details
A	GLN623-PRO632

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Proton donor/acceptor => ECO:0000305|PubMed:29087344, ECO:0007744|PDB:5M4A

Chain	Residue	Details
A	ASP478
A	GLU674

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site_id	SWS_FT_FI2
Number of Residues	5
Details	BINDING: BINDING => ECO:0000269|PubMed:29087344, ECO:0007744|PDB:5N6N

Chain	Residue	Details
A	ASP114
A	ASP116
A	ASN118
A	GLN120
A	ASP125

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site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P13482

Chain	Residue	Details
A	ARG302

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site_id	SWS_FT_FI4
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269|PubMed:29087344, ECO:0007744|PDB:5M4A, ECO:0007744|PDB:5N6N

Chain	Residue	Details
A	TRP309
A	ASN346
A	ARG355
A	GLU424
A	ARG473
A	GLY476

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