5NGZ
Ube2T in complex with fragment EM04
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000209 | biological_process | protein polyubiquitination |
| A | 0003682 | molecular_function | chromatin binding |
| A | 0004842 | molecular_function | ubiquitin-protein transferase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005654 | cellular_component | nucleoplasm |
| A | 0005730 | cellular_component | nucleolus |
| A | 0006281 | biological_process | DNA repair |
| A | 0006513 | biological_process | protein monoubiquitination |
| A | 0006974 | biological_process | DNA damage response |
| A | 0016567 | biological_process | protein ubiquitination |
| A | 0016740 | molecular_function | transferase activity |
| A | 0019787 | molecular_function | ubiquitin-like protein transferase activity |
| A | 0031625 | molecular_function | ubiquitin protein ligase binding |
| A | 0032446 | biological_process | protein modification by small protein conjugation |
| A | 0035519 | biological_process | protein K29-linked ubiquitination |
| A | 0044314 | biological_process | protein K27-linked ubiquitination |
| A | 0051865 | biological_process | protein autoubiquitination |
| A | 0061631 | molecular_function | ubiquitin conjugating enzyme activity |
| A | 0070534 | biological_process | protein K63-linked ubiquitination |
| A | 0070936 | biological_process | protein K48-linked ubiquitination |
| A | 0070979 | biological_process | protein K11-linked ubiquitination |
| A | 0085020 | biological_process | protein K6-linked ubiquitination |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue 2BG A 201 |
| Chain | Residue |
| A | PHE70 |
| A | LEU71 |
| A | PRO73 |
| A | ILE74 |
| A | ASP80 |
| A | SER81 |
| A | TRP146 |
Functional Information from PROSITE/UniProt
| site_id | PS00183 |
| Number of Residues | 16 |
| Details | UBC_1 Ubiquitin-conjugating (UBC) active site signature. YHPNIdsa.GrICLdvL |
| Chain | Residue | Details |
| A | TYR75-LEU90 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Glycyl thioester intermediate => ECO:0000255|PROSITE-ProRule:PRU00388 |
| Chain | Residue | Details |
| A | CYS86 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER184 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16916645, ECO:0000269|PubMed:19111657 |
| Chain | Residue | Details |
| A | LYS91 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733 |
| Chain | Residue | Details |
| A | LYS191 | |
| A | LYS192 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:19111657 |
| Chain | Residue | Details |
| A | LYS182 |
