Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | binding site for residue SAM A 501 |
| Chain | Residue |
| A | LEU290 |
| A | SER322 |
| A | LEU336 |
| A | LEU338 |
| A | LYS349 |
| A | ASN350 |
| A | LEU351 |
| A | MET356 |
| A | HOH607 |
| A | HOH613 |
| A | HOH616 |
| A | THR291 |
| A | ALA292 |
| A | ILE309 |
| A | GLY310 |
| A | PHE312 |
| A | ASP314 |
| A | GLN318 |
| A | THR321 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 502 |
| Chain | Residue |
| A | THR299 |
| A | PHE301 |
| A | ASN368 |
| A | TRP369 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 503 |
| Chain | Residue |
| A | MET298 |
| A | THR299 |
| A | THR300 |
| A | ARG302 |
| A | GLU334 |
| A | HOH622 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 504 |
| Chain | Residue |
| A | ARG236 |
| C | MET215 |
| C | LYS216 |
| C | LEU220 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 505 |
| Chain | Residue |
| A | GLN226 |
| A | THR352 |
| A | ASP354 |
| A | GLN355 |
| A | HOH608 |
| A | HOH623 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | binding site for residue EDO A 506 |
| site_id | AC7 |
| Number of Residues | 20 |
| Details | binding site for residue SAM B 501 |
| Chain | Residue |
| B | LEU290 |
| B | THR291 |
| B | ALA292 |
| B | ILE309 |
| B | GLY310 |
| B | PHE312 |
| B | ASP314 |
| B | GLN318 |
| B | THR321 |
| B | SER322 |
| B | CYS335 |
| B | LEU336 |
| B | LYS349 |
| B | ASN350 |
| B | LEU351 |
| B | MET356 |
| B | HOH609 |
| B | HOH620 |
| B | HOH644 |
| B | HOH660 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue GOL B 502 |
| Chain | Residue |
| B | VAL279 |
| B | ASP280 |
| B | PRO283 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 503 |
| Chain | Residue |
| A | VAL238 |
| A | PRO240 |
| B | ASN213 |
| B | MET215 |
| C | ARG217 |
| C | GLN221 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 504 |
| Chain | Residue |
| B | THR299 |
| B | THR300 |
| B | PHE301 |
| B | GLY367 |
| B | TRP369 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 505 |
| Chain | Residue |
| B | ILE250 |
| B | HIS255 |
| B | TRP266 |
| B | SER273 |
| B | HOH625 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 506 |
| Chain | Residue |
| B | CYS362 |
| B | ASN366 |
| B | GLU371 |
| site_id | AD4 |
| Number of Residues | 20 |
| Details | binding site for residue SAM C 501 |
| Chain | Residue |
| C | HOH615 |
| C | HOH625 |
| C | HOH629 |
| C | LEU290 |
| C | THR291 |
| C | ALA292 |
| C | ILE309 |
| C | GLY310 |
| C | PHE312 |
| C | ASP314 |
| C | GLN318 |
| C | THR321 |
| C | SER322 |
| C | CYS335 |
| C | LEU336 |
| C | LYS349 |
| C | ASN350 |
| C | LEU351 |
| C | MET356 |
| C | HOH610 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue GOL C 502 |
| Chain | Residue |
| C | THR300 |
| C | PHE301 |
| C | GLY367 |
| C | TRP369 |
