5NEZ

crystal structure of variants

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000107	molecular_function	imidazoleglycerol-phosphate synthase activity
A	0000287	molecular_function	magnesium ion binding
A	0005737	cellular_component	cytoplasm
A	0006650	biological_process	glycerophospholipid metabolic process
A	0008654	biological_process	phospholipid biosynthetic process
A	0016740	molecular_function	transferase activity
A	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
A	0046474	biological_process	glycerophospholipid biosynthetic process
A	0046872	molecular_function	metal ion binding
A	0047294	molecular_function	phosphoglycerol geranylgeranyltransferase activity
B	0000107	molecular_function	imidazoleglycerol-phosphate synthase activity
B	0000287	molecular_function	magnesium ion binding
B	0005737	cellular_component	cytoplasm
B	0006650	biological_process	glycerophospholipid metabolic process
B	0008654	biological_process	phospholipid biosynthetic process
B	0016740	molecular_function	transferase activity
B	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
B	0046474	biological_process	glycerophospholipid biosynthetic process
B	0046872	molecular_function	metal ion binding
B	0047294	molecular_function	phosphoglycerol geranylgeranyltransferase activity
C	0000107	molecular_function	imidazoleglycerol-phosphate synthase activity
C	0000287	molecular_function	magnesium ion binding
C	0005737	cellular_component	cytoplasm
C	0006650	biological_process	glycerophospholipid metabolic process
C	0008654	biological_process	phospholipid biosynthetic process
C	0016740	molecular_function	transferase activity
C	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
C	0046474	biological_process	glycerophospholipid biosynthetic process
C	0046872	molecular_function	metal ion binding
C	0047294	molecular_function	phosphoglycerol geranylgeranyltransferase activity
D	0000107	molecular_function	imidazoleglycerol-phosphate synthase activity
D	0000287	molecular_function	magnesium ion binding
D	0005737	cellular_component	cytoplasm
D	0006650	biological_process	glycerophospholipid metabolic process
D	0008654	biological_process	phospholipid biosynthetic process
D	0016740	molecular_function	transferase activity
D	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
D	0046474	biological_process	glycerophospholipid biosynthetic process
D	0046872	molecular_function	metal ion binding
D	0047294	molecular_function	phosphoglycerol geranylgeranyltransferase activity
E	0000107	molecular_function	imidazoleglycerol-phosphate synthase activity
E	0000287	molecular_function	magnesium ion binding
E	0005737	cellular_component	cytoplasm
E	0006650	biological_process	glycerophospholipid metabolic process
E	0008654	biological_process	phospholipid biosynthetic process
E	0016740	molecular_function	transferase activity
E	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
E	0046474	biological_process	glycerophospholipid biosynthetic process
E	0046872	molecular_function	metal ion binding
E	0047294	molecular_function	phosphoglycerol geranylgeranyltransferase activity
F	0000107	molecular_function	imidazoleglycerol-phosphate synthase activity
F	0000287	molecular_function	magnesium ion binding
F	0005737	cellular_component	cytoplasm
F	0006650	biological_process	glycerophospholipid metabolic process
F	0008654	biological_process	phospholipid biosynthetic process
F	0016740	molecular_function	transferase activity
F	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
F	0046474	biological_process	glycerophospholipid biosynthetic process
F	0046872	molecular_function	metal ion binding
F	0047294	molecular_function	phosphoglycerol geranylgeranyltransferase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00112

Chain	Residue	Details
A	ASP25
E	SER54
F	ASP25
F	SER54
A	SER54
B	ASP25
B	SER54
C	ASP25
C	SER54
D	ASP25
D	SER54
E	ASP25

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site_id	SWS_FT_FI2
Number of Residues	18
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00112, ECO:0000269|PubMed:24684232, ECO:0007744|PDB:4MM1

Chain	Residue	Details
A	TYR172
D	TYR172
D	GLY203
D	GLY225
E	TYR172
E	GLY203
E	GLY225
F	TYR172
F	GLY203
F	GLY225
A	GLY203
A	GLY225
B	TYR172
B	GLY203
B	GLY225
C	TYR172
C	GLY203
C	GLY225

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