5N77

Crystal structure of the cytosolic domain of the CorA magnesium channel from Escherichia coli in complex with magnesium

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006824	biological_process	cobalt ion transport
A	0015087	molecular_function	cobalt ion transmembrane transporter activity
A	0015095	molecular_function	magnesium ion transmembrane transporter activity
A	0015693	biological_process	magnesium ion transport
A	0016020	cellular_component	membrane
A	0030001	biological_process	metal ion transport
A	0046873	molecular_function	metal ion transmembrane transporter activity
A	0055085	biological_process	transmembrane transport
B	0006824	biological_process	cobalt ion transport
B	0015087	molecular_function	cobalt ion transmembrane transporter activity
B	0015095	molecular_function	magnesium ion transmembrane transporter activity
B	0015693	biological_process	magnesium ion transport
B	0016020	cellular_component	membrane
B	0030001	biological_process	metal ion transport
B	0046873	molecular_function	metal ion transmembrane transporter activity
B	0055085	biological_process	transmembrane transport
C	0006824	biological_process	cobalt ion transport
C	0015087	molecular_function	cobalt ion transmembrane transporter activity
C	0015095	molecular_function	magnesium ion transmembrane transporter activity
C	0015693	biological_process	magnesium ion transport
C	0016020	cellular_component	membrane
C	0030001	biological_process	metal ion transport
C	0046873	molecular_function	metal ion transmembrane transporter activity
C	0055085	biological_process	transmembrane transport
D	0006824	biological_process	cobalt ion transport
D	0015087	molecular_function	cobalt ion transmembrane transporter activity
D	0015095	molecular_function	magnesium ion transmembrane transporter activity
D	0015693	biological_process	magnesium ion transport
D	0016020	cellular_component	membrane
D	0030001	biological_process	metal ion transport
D	0046873	molecular_function	metal ion transmembrane transporter activity
D	0055085	biological_process	transmembrane transport
E	0006824	biological_process	cobalt ion transport
E	0015087	molecular_function	cobalt ion transmembrane transporter activity
E	0015095	molecular_function	magnesium ion transmembrane transporter activity
E	0015693	biological_process	magnesium ion transport
E	0016020	cellular_component	membrane
E	0030001	biological_process	metal ion transport
E	0046873	molecular_function	metal ion transmembrane transporter activity
E	0055085	biological_process	transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue MG A 301

Chain	Residue
A	ASP58
A	GLU60
A	HOH401
A	HOH405
B	ASP146
B	GLU149

---

site_id	AC2
Number of Residues	5
Details	binding site for residue MG B 301

Chain	Residue
D	GLN252
E	GLN252
A	GLN252
B	GLN252
C	GLN252

---

site_id	AC3
Number of Residues	4
Details	binding site for residue MG B 302

Chain	Residue
B	ASP58
B	GLU60
B	HOH404
B	HOH406

---

site_id	AC4
Number of Residues	5
Details	binding site for residue MG C 301

Chain	Residue
A	GLU142
C	ASP58
C	GLU60
C	HOH401
C	HOH403

---

site_id	AC5
Number of Residues	4
Details	binding site for residue PG0 C 302

Chain	Residue
A	PRO228
C	ARG189
C	LEU190
C	MET193

---

site_id	AC6
Number of Residues	4
Details	binding site for residue MG D 301

Chain	Residue
D	ASP58
D	GLU60
D	HOH403
D	HOH405

---

site_id	AC7
Number of Residues	7
Details	binding site for residue PG0 D 302

Chain	Residue
C	SER225
C	PRO228
C	HIS229
D	ILE59
D	MET193
D	ASP194
D	ARG197

---

site_id	AC8
Number of Residues	4
Details	binding site for residue MG E 301

Chain	Residue
D	HOH407
E	ASP58
E	GLU60
E	HOH403

---

site_id	AC9
Number of Residues	6
Details	binding site for residue PG0 E 302

Chain	Residue
D	PRO228
D	HIS229
D	SER232
E	ARG189
E	MET193
E	HOH410

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	759
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	5
Details	Site: {"description":"Essential for ion permeation","evidences":[{"source":"UniProtKB","id":"Q9WZ31","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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