5N6H
Structure of the membrane integral lipoprotein N-acyltransferase Lnt from E. coli
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0016020 | cellular_component | membrane |
| A | 0016410 | molecular_function | N-acyltransferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| A | 0042158 | biological_process | lipoprotein biosynthetic process |
| B | 0005515 | molecular_function | protein binding |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0016020 | cellular_component | membrane |
| B | 0016410 | molecular_function | N-acyltransferase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016746 | molecular_function | acyltransferase activity |
| B | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| B | 0042158 | biological_process | lipoprotein biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue OLC A 601 |
| Chain | Residue |
| A | ALA22 |
| A | THR25 |
| A | LEU26 |
| A | TYR31 |
| A | SER70 |
| A | ASN73 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue OLC A 602 |
| Chain | Residue |
| A | PHE49 |
| A | ASN50 |
| A | VAL188 |
| A | ARG13 |
| A | ALA46 |
| A | LEU47 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue OLC A 603 |
| Chain | Residue |
| A | TRP121 |
| A | ALA171 |
| A | MET178 |
| A | ASN191 |
| A | VAL197 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue OLC A 604 |
| Chain | Residue |
| A | GLN10 |
| A | ARG52 |
| A | GLN55 |
| A | ALA58 |
| A | PHE61 |
| A | OLC606 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue OLC A 605 |
| Chain | Residue |
| A | LEU131 |
| A | VAL134 |
| A | ASN488 |
| A | TRP489 |
| A | TRP492 |
| A | GLY499 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue OLC A 606 |
| Chain | Residue |
| A | ARG52 |
| A | LEU54 |
| A | LEU107 |
| A | ARG114 |
| A | OLC604 |
| B | ILE211 |
| B | GLN212 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue OLC A 607 |
| Chain | Residue |
| A | LEU18 |
| A | CYS62 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue OLC A 608 |
| Chain | Residue |
| A | VAL134 |
| A | PHE137 |
| A | GLU170 |
| A | ASN488 |
| A | TRP492 |
| A | GOL614 |
| site_id | AC9 |
| Number of Residues | 1 |
| Details | binding site for residue OLC A 609 |
| Chain | Residue |
| A | ARG485 |
| site_id | AD1 |
| Number of Residues | 2 |
| Details | binding site for residue OLC A 610 |
| Chain | Residue |
| A | PHE341 |
| B | TRP192 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue OLC A 611 |
| Chain | Residue |
| A | ALA22 |
| A | GLY69 |
| A | ASN73 |
| A | TYR76 |
| A | VAL94 |
| A | VAL95 |
| site_id | AD3 |
| Number of Residues | 2 |
| Details | binding site for residue OLC A 612 |
| Chain | Residue |
| A | ARG190 |
| A | TRP192 |
| site_id | AD4 |
| Number of Residues | 1 |
| Details | binding site for residue GOL A 613 |
| Chain | Residue |
| A | LEU143 |
| site_id | AD5 |
| Number of Residues | 2 |
| Details | binding site for residue GOL A 614 |
| Chain | Residue |
| A | TRP141 |
| A | OLC608 |
| site_id | AD6 |
| Number of Residues | 2 |
| Details | binding site for residue GOL A 615 |
| Chain | Residue |
| A | ALA203 |
| A | PHE206 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 616 |
| Chain | Residue |
| A | GLU239 |
| A | LEU243 |
| A | GLN277 |
| A | PRO279 |
| A | PHE280 |
| site_id | AD8 |
| Number of Residues | 2 |
| Details | binding site for residue GOL A 617 |
| Chain | Residue |
| A | GLN10 |
| A | ARG11 |
| site_id | AD9 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 618 |
| Chain | Residue |
| A | GLY258 |
| A | LYS259 |
| A | SER261 |
| A | LYS291 |
| A | GLY292 |
| A | SER293 |
| site_id | AE1 |
| Number of Residues | 4 |
| Details | binding site for residue OLC B 601 |
| Chain | Residue |
| B | ALA22 |
| B | LEU26 |
| B | TYR31 |
| B | SER70 |
| site_id | AE2 |
| Number of Residues | 8 |
| Details | binding site for residue OLC B 602 |
| Chain | Residue |
| A | PRO86 |
| A | PRO88 |
| A | VAL89 |
| B | THR120 |
| B | TRP121 |
| B | LEU122 |
| B | ALA125 |
| B | GOL610 |
| site_id | AE3 |
| Number of Residues | 7 |
| Details | binding site for residue OLC B 603 |
| Chain | Residue |
| B | ILE7 |
| B | ARG13 |
| B | PHE20 |
| B | ALA46 |
| B | LEU47 |
| B | PHE49 |
| B | ASN50 |
| site_id | AE4 |
| Number of Residues | 6 |
| Details | binding site for residue OLC B 604 |
| Chain | Residue |
| B | GLU394 |
| B | ASP398 |
| B | TRP489 |
| B | TRP492 |
| B | ALA496 |
| B | GLY499 |
| site_id | AE5 |
| Number of Residues | 4 |
| Details | binding site for residue OLC B 605 |
| Chain | Residue |
| B | TYR210 |
| B | ILE211 |
| B | GLN212 |
| A | LEU54 |
| site_id | AE6 |
| Number of Residues | 4 |
| Details | binding site for residue OLC B 606 |
| Chain | Residue |
| B | ASP32 |
| B | VAL33 |
| B | TRP34 |
| B | PRO35 |
| site_id | AE7 |
| Number of Residues | 2 |
| Details | binding site for residue GOL B 607 |
| Chain | Residue |
| B | PHE137 |
| B | TRP141 |
| site_id | AE8 |
| Number of Residues | 3 |
| Details | binding site for residue GOL B 608 |
| Chain | Residue |
| B | TRP141 |
| B | LEU143 |
| B | GOL609 |
| site_id | AE9 |
| Number of Residues | 3 |
| Details | binding site for residue GOL B 609 |
| Chain | Residue |
| B | LEU143 |
| B | PRO346 |
| B | GOL608 |
| site_id | AF1 |
| Number of Residues | 3 |
| Details | binding site for residue GOL B 610 |
| Chain | Residue |
| B | THR120 |
| B | TRP121 |
| B | OLC602 |
| site_id | AF2 |
| Number of Residues | 2 |
| Details | binding site for residue GOL B 611 |
| Chain | Residue |
| B | ARG114 |
| B | LEU354 |
| site_id | AF3 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 612 |
| Chain | Residue |
| B | GLY258 |
| B | LYS259 |
| B | GLY292 |
| B | ASN378 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 306 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"28675161","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 372 |
| Details | Topological domain: {"description":"Periplasmic","evidences":[{"source":"PubMed","id":"28675161","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28885614","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 14 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"28675161","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28885614","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 249 |
| Details | Domain: {"description":"CN hydrolase","evidences":[{"source":"HAMAP-Rule","id":"MF_01148","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_01148","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"28675161","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01148","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"28675161","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"HAMAP-Rule","id":"MF_01148","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"28675161","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
