5N4B
Prolyl oligopeptidase B from Galerina marginata bound to 25mer macrocyclization substrate - S577A mutant
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006508 | biological_process | proteolysis |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| A | 0070012 | molecular_function | oligopeptidase activity |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006508 | biological_process | proteolysis |
| B | 0008236 | molecular_function | serine-type peptidase activity |
| B | 0070012 | molecular_function | oligopeptidase activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | MOD_RES: (3R,4S)-4-hydroxyisoleucine; in form gamma-amanitin => ECO:0000250|UniProtKB:P85421 |
| Chain | Residue | Details |
| D | ILE1 | |
| C | ILE1 | |
| A | HIS698 | |
| B | ALA577 | |
| B | ASP661 | |
| B | HIS698 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: 4-hydroxyproline => ECO:0000250|UniProtKB:P85421 |
| Chain | Residue | Details |
| D | PRO8 | |
| C | PRO8 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | CROSSLNK: Cyclopeptide (Ile-Pro) => ECO:0000250|UniProtKB:P85421 |
| Chain | Residue | Details |
| D | ILE1 | |
| D | PRO8 | |
| C | ILE1 | |
| C | PRO8 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | CROSSLNK: 2'-cysteinyl-6'-hydroxytryptophan sulfoxide (Trp-Cys) => ECO:0000250|UniProtKB:P85421 |
| Chain | Residue | Details |
| D | TRP2 | |
| D | CYS6 | |
| C | TRP2 | |
| C | CYS6 |
