5MQ4
Crystal Structure of the leucine zipper of human PRKCBP1
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 1201 |
| Chain | Residue |
| A | ARG1011 |
| A | ARG1014 |
| F | ARG1012 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 1202 |
| Chain | Residue |
| A | CYS1089 |
| A | CYS1090 |
| A | HIS1108 |
| A | CYS1112 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 1203 |
| Chain | Residue |
| A | CYS1096 |
| A | CYS1100 |
| A | CYS1078 |
| A | CYS1081 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 1201 |
| Chain | Residue |
| B | ARG1011 |
| B | ARG1014 |
| D | ARG1012 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 1202 |
| Chain | Residue |
| B | CYS1078 |
| B | CYS1081 |
| B | CYS1096 |
| B | CYS1100 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 1203 |
| Chain | Residue |
| B | CYS1089 |
| B | CYS1090 |
| B | HIS1108 |
| B | CYS1112 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue ZN C 1201 |
| Chain | Residue |
| C | CYS1089 |
| C | CYS1090 |
| C | HIS1108 |
| C | CYS1112 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue ZN C 1202 |
| Chain | Residue |
| C | CYS1078 |
| C | CYS1081 |
| C | CYS1096 |
| C | CYS1100 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 D 1201 |
| Chain | Residue |
| A | GLN1076 |
| A | TYR1088 |
| A | ASN1092 |
| A | SER1094 |
| D | GLN1076 |
| D | ASN1092 |
| D | SER1094 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN D 1202 |
| Chain | Residue |
| D | CYS1089 |
| D | CYS1090 |
| D | HIS1108 |
| D | CYS1112 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN D 1203 |
| Chain | Residue |
| D | CYS1078 |
| D | CYS1081 |
| D | CYS1096 |
| D | CYS1100 |
| site_id | AD3 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 E 1201 |
| Chain | Residue |
| C | GLN1076 |
| C | CYS1090 |
| C | ASN1092 |
| E | GLN1076 |
| E | TYR1088 |
| E | ASN1092 |
| E | SER1094 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue ZN E 1202 |
| Chain | Residue |
| E | CYS1089 |
| E | CYS1090 |
| E | HIS1108 |
| E | CYS1112 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue ZN E 1203 |
| Chain | Residue |
| E | CYS1078 |
| E | CYS1081 |
| E | CYS1096 |
| E | CYS1100 |
| site_id | AD6 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 F 1201 |
| Chain | Residue |
| B | GLN1076 |
| B | CYS1090 |
| B | ASN1092 |
| B | SER1094 |
| F | GLN1076 |
| F | ASN1092 |
| F | SER1094 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue ZN F 1202 |
| Chain | Residue |
| F | CYS1089 |
| F | CYS1090 |
| F | HIS1108 |
| F | CYS1112 |
| F | THR1113 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue ZN F 1203 |
| Chain | Residue |
| F | CYS1078 |
| F | CYS1081 |
| F | CYS1096 |
| F | CYS1100 |
Functional Information from PROSITE/UniProt
| site_id | PS01360 |
| Number of Residues | 35 |
| Details | ZF_MYND_1 Zinc finger MYND-type signature. Can..Ckkeaify..........C..CwntsYCdypCqqahwpe..Hmks.C |
| Chain | Residue | Details |
| A | CYS1078-CYS1112 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 204 |
| Details | Zinc finger: {"description":"MYND-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00134","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 204 |
| Details | Region: {"description":"Required for recruitment to DNA damage sites and for interaction with the NuRD complex, CHD4, HDAC1, HDAC2 and KDM1A","evidences":[{"source":"PubMed","id":"25593309","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27732854","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 48 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00134","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
