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5MPD

26S proteasome in presence of ATP (s1)

Functional Information from GO Data
ChainGOidnamespacecontents
N0000502cellular_componentproteasome complex
N0004175molecular_functionendopeptidase activity
N0005515molecular_functionprotein binding
N0005634cellular_componentnucleus
N0006511biological_processubiquitin-dependent protein catabolic process
N0008540cellular_componentproteasome regulatory particle, base subcomplex
N0030234molecular_functionenzyme regulator activity
N0031625molecular_functionubiquitin protein ligase binding
N0034515cellular_componentproteasome storage granule
N0042176biological_processregulation of protein catabolic process
N0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
N0043248biological_processproteasome assembly
O0000502cellular_componentproteasome complex
O0005198molecular_functionstructural molecule activity
O0005515molecular_functionprotein binding
O0005634cellular_componentnucleus
O0005829cellular_componentcytosol
O0006511biological_processubiquitin-dependent protein catabolic process
O0008541cellular_componentproteasome regulatory particle, lid subcomplex
O0034515cellular_componentproteasome storage granule
O0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
O0043248biological_processproteasome assembly
P0000338biological_processprotein deneddylation
P0000502cellular_componentproteasome complex
P0005515molecular_functionprotein binding
P0005737cellular_componentcytoplasm
P0008180cellular_componentCOP9 signalosome
P0008541cellular_componentproteasome regulatory particle, lid subcomplex
P0034515cellular_componentproteasome storage granule
P0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
Q0000502cellular_componentproteasome complex
Q0005198molecular_functionstructural molecule activity
Q0005515molecular_functionprotein binding
Q0006511biological_processubiquitin-dependent protein catabolic process
Q0008541cellular_componentproteasome regulatory particle, lid subcomplex
Q0034515cellular_componentproteasome storage granule
Q0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
Q0043248biological_processproteasome assembly
R0000502cellular_componentproteasome complex
R0005198molecular_functionstructural molecule activity
R0005515molecular_functionprotein binding
R0005634cellular_componentnucleus
R0005838cellular_componentproteasome regulatory particle
R0006511biological_processubiquitin-dependent protein catabolic process
R0008541cellular_componentproteasome regulatory particle, lid subcomplex
R0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
S0000502cellular_componentproteasome complex
S0003674molecular_functionmolecular_function
S0005515molecular_functionprotein binding
S0006511biological_processubiquitin-dependent protein catabolic process
S0008541cellular_componentproteasome regulatory particle, lid subcomplex
S0030234molecular_functionenzyme regulator activity
S0042176biological_processregulation of protein catabolic process
S0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
T0000502cellular_componentproteasome complex
T0003674molecular_functionmolecular_function
T0005515molecular_functionprotein binding
T0005634cellular_componentnucleus
T0005829cellular_componentcytosol
T0005838cellular_componentproteasome regulatory particle
T0006508biological_processproteolysis
T0006511biological_processubiquitin-dependent protein catabolic process
T0008541cellular_componentproteasome regulatory particle, lid subcomplex
T0034515cellular_componentproteasome storage granule
T0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
U0000502cellular_componentproteasome complex
U0005515molecular_functionprotein binding
U0005838cellular_componentproteasome regulatory particle
U0006511biological_processubiquitin-dependent protein catabolic process
U0008233molecular_functionpeptidase activity
U0008237molecular_functionmetallopeptidase activity
U0008541cellular_componentproteasome regulatory particle, lid subcomplex
U0034515cellular_componentproteasome storage granule
U0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
V0000266biological_processmitochondrial fission
V0000502cellular_componentproteasome complex
V0004843molecular_functioncysteine-type deubiquitinase activity
V0005515molecular_functionprotein binding
V0005634cellular_componentnucleus
V0005739cellular_componentmitochondrion
V0005829cellular_componentcytosol
V0006508biological_processproteolysis
V0008233molecular_functionpeptidase activity
V0008234molecular_functioncysteine-type peptidase activity
V0008237molecular_functionmetallopeptidase activity
V0008270molecular_functionzinc ion binding
V0008541cellular_componentproteasome regulatory particle, lid subcomplex
V0016559biological_processperoxisome fission
V0016579biological_processprotein deubiquitination
V0016787molecular_functionhydrolase activity
V0034515cellular_componentproteasome storage granule
V0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
V0043248biological_processproteasome assembly
V0046872molecular_functionmetal ion binding
V0070628molecular_functionproteasome binding
V0140492molecular_functionmetal-dependent deubiquitinase activity
V1902906biological_processproteasome storage granule assembly
W0000502cellular_componentproteasome complex
W0005515molecular_functionprotein binding
W0005634cellular_componentnucleus
W0005829cellular_componentcytosol
W0006511biological_processubiquitin-dependent protein catabolic process
W0008540cellular_componentproteasome regulatory particle, base subcomplex
W0031593molecular_functionpolyubiquitin modification-dependent protein binding
W0036435molecular_functionK48-linked polyubiquitin modification-dependent protein binding
W0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
W0043248biological_processproteasome assembly
X0000502cellular_componentproteasome complex
X0005515molecular_functionprotein binding
X0005634cellular_componentnucleus
X0005737cellular_componentcytoplasm
X0006511biological_processubiquitin-dependent protein catabolic process
X0008541cellular_componentproteasome regulatory particle, lid subcomplex
X0034515cellular_componentproteasome storage granule
X0043130molecular_functionubiquitin binding
X0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
X0061133molecular_functionendopeptidase activator activity
X0070628molecular_functionproteasome binding
Y0000502cellular_componentproteasome complex
Y0000724biological_processdouble-strand break repair via homologous recombination
Y0003674molecular_functionmolecular_function
Y0005515molecular_functionprotein binding
Y0005829cellular_componentcytosol
Y0006406biological_processmRNA export from nucleus
Y0006457biological_processprotein folding
Y0006511biological_processubiquitin-dependent protein catabolic process
Y0008541cellular_componentproteasome regulatory particle, lid subcomplex
Y0030447biological_processfilamentous growth
Y0034515cellular_componentproteasome storage granule
Y0035753biological_processmaintenance of DNA trinucleotide repeats
Y0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
Y0043248biological_processproteasome assembly
Y0044183molecular_functionprotein folding chaperone
Y0045944biological_processpositive regulation of transcription by RNA polymerase II
Y0051726biological_processregulation of cell cycle
Y0060090molecular_functionmolecular adaptor activity
Y0070390cellular_componenttranscription export complex 2
Y0072742biological_processSAGA complex localization to transcription regulatory region
Z0000502cellular_componentproteasome complex
Z0004175molecular_functionendopeptidase activity
Z0005515molecular_functionprotein binding
Z0005634cellular_componentnucleus
Z0005737cellular_componentcytoplasm
Z0005783cellular_componentendoplasmic reticulum
Z0006511biological_processubiquitin-dependent protein catabolic process
Z0008540cellular_componentproteasome regulatory particle, base subcomplex
Z0030234molecular_functionenzyme regulator activity
Z0030674molecular_functionprotein-macromolecule adaptor activity
Z0034515cellular_componentproteasome storage granule
Z0042176biological_processregulation of protein catabolic process
Z0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
Functional Information from PROSITE/UniProt
site_idPS00387
Number of Residues7
DetailsPPASE Inorganic pyrophosphatase signature. DDDEIDV
ChainResidueDetails
UASP243-VAL249

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: N-acetylserine => ECO:0000269|PubMed:12504901
ChainResidueDetails
USER2
RSER77
VASP122

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:19779198
ChainResidueDetails
USER314
USER317

site_idSWS_FT_FI3
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:15665377, ECO:0007744|PubMed:17330950, ECO:0007744|PubMed:19779198
ChainResidueDetails
USER319
XSER140

site_idSWS_FT_FI4
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:19779198
ChainResidueDetails
UTHR327
ZSER695

217705

PDB entries from 2024-03-27

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