Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004713 | molecular_function | protein tyrosine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0004713 | molecular_function | protein tyrosine kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue 7O3 A 901 |
| Chain | Residue |
| A | ALA649 |
| A | SER761 |
| A | ASP762 |
| A | HOH1047 |
| A | HOH1088 |
| A | LYS651 |
| A | GLU668 |
| A | THR697 |
| A | GLU698 |
| A | PHE699 |
| A | MET700 |
| A | CYS703 |
| A | LEU751 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 902 |
| Chain | Residue |
| A | ARG678 |
| A | ARG682 |
| A | LYS759 |
| A | HOH1013 |
| A | HOH1045 |
| A | HOH1076 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 903 |
| Chain | Residue |
| A | SER707 |
| A | ARG710 |
| A | GLN711 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 904 |
| Chain | Residue |
| A | ARG748 |
| A | TRP790 |
| A | ARG823 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 902 |
| Chain | Residue |
| A | ARG678 |
| B | ARG678 |
| B | ASN753 |
| B | VAL757 |
| B | LYS759 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 903 |
| Chain | Residue |
| B | TRP790 |
| B | ARG823 |
| B | HOH1009 |
| B | HOH1088 |
| site_id | AC7 |
| Number of Residues | 14 |
| Details | binding site for Di-peptide 7O3 B 901 and CYS B 703 |
| Chain | Residue |
| B | ALA649 |
| B | LYS651 |
| B | GLU668 |
| B | THR697 |
| B | GLU698 |
| B | MET700 |
| B | GLU701 |
| B | ASN702 |
| B | ALA704 |
| B | LEU751 |
| B | VAL752 |
| B | ASP762 |
| B | HOH1048 |
| B | HOH1080 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 27 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGAGEFGEVYkGrlklpgkreiy.......VAIK |
| Chain | Residue | Details |
| A | ILE625-LYS651 | |
| site_id | PS00109 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. YVHrDLAARNILV |
| Chain | Residue | Details |
| A | TYR740-VAL752 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10028","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]} |
