5MIU
G307E variant of Murine Apoptosis Inducing Factor (oxidized state)
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 27 |
| Details | binding site for residue FAD A 701 |
| Chain | Residue |
| A | GLY137 |
| A | PRO172 |
| A | LYS176 |
| A | LYS231 |
| A | VAL232 |
| A | THR259 |
| A | GLY260 |
| A | ARG284 |
| A | LYS285 |
| A | LEU310 |
| A | ASN402 |
| A | GLY138 |
| A | LEU405 |
| A | GLY436 |
| A | ASP437 |
| A | HIS453 |
| A | HIS454 |
| A | ALA457 |
| A | PHE481 |
| A | TRP482 |
| A | GLY139 |
| A | THR140 |
| A | ALA141 |
| A | VAL161 |
| A | GLU163 |
| A | ASP164 |
| A | ARG171 |
| site_id | AC2 |
| Number of Residues | 28 |
| Details | binding site for residue FAD B 701 |
| Chain | Residue |
| B | GLY137 |
| B | GLY138 |
| B | GLY139 |
| B | THR140 |
| B | ALA141 |
| B | VAL161 |
| B | GLU163 |
| B | ASP164 |
| B | ARG171 |
| B | PRO172 |
| B | LYS176 |
| B | LYS231 |
| B | VAL232 |
| B | ALA258 |
| B | THR259 |
| B | GLY260 |
| B | ARG284 |
| B | LEU310 |
| B | ASN402 |
| B | LEU405 |
| B | GLY436 |
| B | ASP437 |
| B | GLU452 |
| B | HIS453 |
| B | HIS454 |
| B | ALA457 |
| B | PHE481 |
| B | TRP482 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:11967568, ECO:0000269|PubMed:19447115, ECO:0007744|PDB:3GD3, ECO:0007744|PDB:3GD4 |
| Chain | Residue | Details |
| A | GLY137 | |
| A | ARG171 | |
| A | VAL232 | |
| A | ARG284 | |
| B | GLY137 | |
| B | ARG171 | |
| B | VAL232 | |
| B | ARG284 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:11967568, ECO:0000269|PubMed:19447115, ECO:0007744|PDB:3GD4 |
| Chain | Residue | Details |
| A | GLU163 | |
| A | HIS453 | |
| B | GLU163 | |
| B | HIS453 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:11967568, ECO:0000269|PubMed:19447115, ECO:0007744|PDB:3GD3 |
| Chain | Residue | Details |
| A | LYS176 | |
| B | LYS176 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:O95831 |
| Chain | Residue | Details |
| A | TRP195 | |
| A | GLU492 | |
| A | ASN582 | |
| B | TRP195 | |
| B | GLU492 | |
| B | ASN582 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:19447115, ECO:0007744|PDB:3GD4 |
| Chain | Residue | Details |
| A | GLU307 | |
| B | GLY398 | |
| B | GLU452 | |
| B | TRP482 | |
| A | GLU335 | |
| A | LYS341 | |
| A | GLY398 | |
| A | GLU452 | |
| A | TRP482 | |
| B | GLU307 | |
| B | GLU335 | |
| B | LYS341 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:19447115, ECO:0007744|PDB:3GD3, ECO:0007744|PDB:3GD4 |
| Chain | Residue | Details |
| A | ASP437 | |
| B | ASP437 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-succinyllysine => ECO:0007744|PubMed:23806337 |
| Chain | Residue | Details |
| A | LYS108 | |
| B | LYS108 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 10 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:O95831 |
| Chain | Residue | Details |
| A | SER115 | |
| B | SER529 | |
| A | SER267 | |
| A | SER370 | |
| A | SER523 | |
| A | SER529 | |
| B | SER115 | |
| B | SER267 | |
| B | SER370 | |
| B | SER523 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 4 |
| Details | MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:23576753 |
| Chain | Residue | Details |
| A | LYS387 | |
| A | LYS592 | |
| B | LYS387 | |
| B | LYS592 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:O95831 |
| Chain | Residue | Details |
| A | THR520 | |
| B | THR520 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 4 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:O95831 |
| Chain | Residue | Details |
| A | LYS254 | |
| B | LYS254 |
