Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 301 |
| Chain | Residue |
| A | SER148 |
| A | PRO149 |
| A | HOH407 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 302 |
| Chain | Residue |
| A | GLU86 |
| C | ARG33 |
| C | GLN37 |
| C | GLU72 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 303 |
| Chain | Residue |
| A | HOH402 |
| A | GLU67 |
| A | SER106 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue CA A 304 |
| Chain | Residue |
| A | PRO65 |
| A | GLU67 |
| A | HOH418 |
| B | PRO191 |
| B | GLU193 |
| B | HOH407 |
| D | HOH486 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue CA A 305 |
| Chain | Residue |
| A | GLU282 |
| A | GLU285 |
| A | HOH482 |
| D | GLU128 |
| D | HOH437 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue CA A 306 |
| Chain | Residue |
| A | PRO149 |
| A | GLU151 |
| A | HOH440 |
| A | HOH505 |
| B | PRO107 |
| B | GLU109 |
| B | HOH412 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue CA A 307 |
| Chain | Residue |
| A | PRO191 |
| A | GLU193 |
| A | HOH438 |
| A | HOH504 |
| B | PRO65 |
| B | GLU67 |
| B | HOH449 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue CA A 308 |
| Chain | Residue |
| A | PRO233 |
| A | GLU235 |
| A | EDO309 |
| A | HOH494 |
| B | PRO23 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 309 |
| Chain | Residue |
| A | PRO233 |
| A | ASN234 |
| A | GLU235 |
| A | CA308 |
| B | PRO23 |
| B | ASP24 |
| B | GLN25 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 310 |
| Chain | Residue |
| A | PRO107 |
| A | GLU109 |
| A | HOH436 |
| B | PRO149 |
| B | GLU151 |
| B | HOH436 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue CA A 311 |
| Chain | Residue |
| A | PRO23 |
| A | GLN25 |
| B | PRO233 |
| B | GLU235 |
| B | HOH422 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 301 |
| Chain | Residue |
| B | TRP117 |
| B | ASN121 |
| B | HOH466 |
| site_id | AD4 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 302 |
| Chain | Residue |
| B | SER106 |
| B | HOH438 |
| site_id | AD5 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 303 |
| Chain | Residue |
| B | SER147 |
| B | GLN186 |
| B | HOH432 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue CA B 304 |
| Chain | Residue |
| A | ASP219 |
| B | GLU285 |
| B | GLU288 |
| B | HOH411 |
| B | HOH464 |
| site_id | AD7 |
| Number of Residues | 2 |
| Details | binding site for residue EDO C 301 |
| Chain | Residue |
| C | SER148 |
| C | PRO149 |
| site_id | AD8 |
| Number of Residues | 5 |
| Details | binding site for residue EDO C 302 |
| Chain | Residue |
| A | SER30 |
| A | ARG33 |
| C | GLU261 |
| C | HOH409 |
| E | ARG7 |
| site_id | AD9 |
| Number of Residues | 6 |
| Details | binding site for residue CA C 303 |
| Chain | Residue |
| B | HOH444 |
| B | HOH468 |
| C | PRO65 |
| C | GLU67 |
| D | PRO191 |
| D | GLU193 |
| site_id | AE1 |
| Number of Residues | 5 |
| Details | binding site for residue CA C 304 |
| Chain | Residue |
| C | PRO107 |
| C | GLU109 |
| D | PRO149 |
| D | GLU151 |
| D | HOH430 |
| site_id | AE2 |
| Number of Residues | 6 |
| Details | binding site for residue CA C 305 |
| Chain | Residue |
| C | PRO149 |
| C | GLU151 |
| C | HOH479 |
| D | PRO107 |
| D | GLU109 |
| D | HOH406 |
| site_id | AE3 |
| Number of Residues | 7 |
| Details | binding site for residue CA C 306 |
| Chain | Residue |
| C | HOH413 |
| D | PRO65 |
| D | GLU67 |
| D | HOH413 |
| A | HOH485 |
| C | PRO191 |
| C | GLU193 |
| site_id | AE4 |
| Number of Residues | 5 |
| Details | binding site for residue CA C 307 |
| Chain | Residue |
| C | PRO233 |
| C | GLU235 |
| C | HOH497 |
| D | PRO23 |
| D | GLN25 |
| site_id | AE5 |
| Number of Residues | 5 |
| Details | binding site for residue CA C 308 |
| Chain | Residue |
| B | SER124 |
| B | GLY125 |
| B | HOH418 |
| B | HOH474 |
| C | SER292 |
| site_id | AE6 |
| Number of Residues | 2 |
| Details | binding site for residue CA C 309 |
| site_id | AE7 |
| Number of Residues | 5 |
| Details | binding site for residue CA C 310 |
| Chain | Residue |
| B | SER166 |
| B | GLY167 |
| B | SER208 |
| B | HOH403 |
| C | GLU288 |
| site_id | AE8 |
| Number of Residues | 5 |
| Details | binding site for residue CA C 311 |
| Chain | Residue |
| B | HOH446 |
| C | PRO23 |
| C | GLN25 |
| D | PRO233 |
| D | GLU235 |
| site_id | AE9 |
| Number of Residues | 1 |
| Details | binding site for residue EDO D 301 |
| site_id | AF1 |
| Number of Residues | 7 |
| Details | binding site for residue EDO D 302 |
| Chain | Residue |
| A | ASN127 |
| A | SER166 |
| A | HOH478 |
| D | ASN127 |
| D | SER166 |
| D | HOH420 |
| D | HOH465 |
| site_id | AF2 |
| Number of Residues | 10 |
| Details | binding site for residue EDO D 303 |
| Chain | Residue |
| A | GLU128 |
| A | GLN131 |
| A | ASP135 |
| A | GLU170 |
| A | HOH417 |
| D | SER246 |
| D | GLU282 |
| D | GLU285 |
| D | HOH460 |
| D | HOH467 |
| site_id | AF3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO D 304 |
| Chain | Residue |
| D | SER82 |
| D | GLY83 |
| D | ASN121 |
| D | SER124 |
| site_id | AF4 |
| Number of Residues | 2 |
| Details | binding site for residue EDO D 305 |
| Chain | Residue |
| D | HOH432 |
| D | HOH436 |
| site_id | AF5 |
| Number of Residues | 4 |
| Details | binding site for residue CA D 306 |
| Chain | Residue |
| D | GLN18 |
| D | ASN21 |
| D | GLU288 |
| D | HOH474 |
