Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0016491 | molecular_function | oxidoreductase activity |
A | 0016702 | molecular_function | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen |
A | 0034440 | biological_process | lipid oxidation |
A | 0046872 | molecular_function | metal ion binding |
A | 0050473 | molecular_function | arachidonate 15-lipoxygenase activity |
B | 0016491 | molecular_function | oxidoreductase activity |
B | 0016702 | molecular_function | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen |
B | 0034440 | biological_process | lipid oxidation |
B | 0046872 | molecular_function | metal ion binding |
B | 0050473 | molecular_function | arachidonate 15-lipoxygenase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | binding site for residue FE A 1001 |
Chain | Residue |
A | HIS257 |
A | HIS262 |
A | HIS449 |
A | ASN453 |
A | ILE569 |
A | HOH1225 |
site_id | AC2 |
Number of Residues | 9 |
Details | binding site for residue GOL A 1002 |
Chain | Residue |
A | ILE73 |
B | THR68 |
B | LEU69 |
B | SER71 |
B | ILE73 |
B | GOL1003 |
A | THR68 |
A | LEU69 |
A | SER71 |
site_id | AC3 |
Number of Residues | 7 |
Details | binding site for residue GOL A 1003 |
Chain | Residue |
A | GLY172 |
A | ARG173 |
A | ASP312 |
A | THR318 |
A | LEU319 |
A | HOH1117 |
A | HOH1157 |
site_id | AC4 |
Number of Residues | 5 |
Details | binding site for residue IMD A 1004 |
Chain | Residue |
A | ARG57 |
A | GLN303 |
A | TYR310 |
A | HOH1122 |
A | HOH1141 |
site_id | AC5 |
Number of Residues | 3 |
Details | binding site for residue IMD A 1005 |
Chain | Residue |
A | TYR510 |
A | SER561 |
A | ASN562 |
site_id | AC6 |
Number of Residues | 2 |
Details | binding site for residue CL A 1006 |
Chain | Residue |
A | LYS141 |
A | THR230 |
site_id | AC7 |
Number of Residues | 6 |
Details | binding site for residue FE B 1001 |
Chain | Residue |
B | HIS257 |
B | HIS262 |
B | HIS449 |
B | ASN453 |
B | ILE569 |
B | HOH1174 |
site_id | AC8 |
Number of Residues | 7 |
Details | binding site for residue GOL B 1002 |
Chain | Residue |
B | GLY172 |
B | ARG173 |
B | ASP312 |
B | THR318 |
B | LEU319 |
B | HOH1135 |
B | HOH1209 |
site_id | AC9 |
Number of Residues | 4 |
Details | binding site for residue GOL B 1003 |
Chain | Residue |
A | GLU74 |
A | GOL1002 |
B | ASN72 |
B | GLU74 |
site_id | AD1 |
Number of Residues | 3 |
Details | binding site for residue IMD B 1004 |
Chain | Residue |
B | TYR510 |
B | SER561 |
B | ASN562 |
site_id | AD2 |
Number of Residues | 5 |
Details | binding site for residue IMD B 1005 |
Chain | Residue |
B | ARG57 |
B | GLN303 |
B | TYR310 |
B | HOH1101 |
B | HOH1179 |
site_id | AD3 |
Number of Residues | 4 |
Details | binding site for residue IMD B 1006 |
Chain | Residue |
A | THR420 |
A | GLY421 |
A | VAL423 |
A | SER424 |
Functional Information from PROSITE/UniProt
site_id | PS00711 |
Number of Residues | 15 |
Details | LIPOXYGENASE_1 Lipoxygenases iron-binding region signature 1. HEaisHlARTHLIlE |
Chain | Residue | Details |
A | HIS252-GLU266 | |