5M3B
Structure of cobinamide-bound BtuF mutant W66L, the periplasmic vitamin B12 binding protein in E.coli
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue CYN A 301 |
| Chain | Residue |
| A | GLU245 |
| A | CBY302 |
| A | CYN303 |
| A | HOH414 |
| A | HOH553 |
| site_id | AC2 |
| Number of Residues | 24 |
| Details | binding site for residue CBY A 302 |
| Chain | Residue |
| A | TRP85 |
| A | GLY87 |
| A | PHE162 |
| A | PHE168 |
| A | TRP196 |
| A | ASP242 |
| A | GLU245 |
| A | ARG246 |
| A | CYN301 |
| A | CYN303 |
| A | GOL304 |
| A | HOH402 |
| A | HOH417 |
| A | HOH427 |
| A | HOH434 |
| A | HOH454 |
| A | HOH506 |
| A | HOH548 |
| A | HOH561 |
| A | HOH571 |
| A | PRO31 |
| A | ALA32 |
| A | TYR50 |
| A | LEU66 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue CYN A 303 |
| Chain | Residue |
| A | TRP85 |
| A | CYN301 |
| A | CBY302 |
| A | GOL304 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 304 |
| Chain | Residue |
| A | SER49 |
| A | LEU66 |
| A | CBY302 |
| A | CYN303 |
| site_id | AC5 |
| Number of Residues | 24 |
| Details | binding site for residue CBY B 301 |
| Chain | Residue |
| B | PRO31 |
| B | ALA32 |
| B | TYR50 |
| B | LEU66 |
| B | TRP85 |
| B | GLY87 |
| B | PHE162 |
| B | PHE168 |
| B | TRP196 |
| B | ASP242 |
| B | GLU245 |
| B | ARG246 |
| B | CYN302 |
| B | GOL303 |
| B | HOH408 |
| B | HOH412 |
| B | HOH423 |
| B | HOH430 |
| B | HOH441 |
| B | HOH484 |
| B | HOH494 |
| B | HOH531 |
| B | HOH575 |
| B | HOH576 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue CYN B 302 |
| Chain | Residue |
| B | GLU245 |
| B | CBY301 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | binding site for residue GOL B 303 |
| Chain | Residue |
| B | LEU29 |
| B | SER48 |
| B | SER49 |
| B | TYR50 |
| B | LEU66 |
| B | TRP85 |
| B | CBY301 |
| B | HOH406 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 304 |
| Chain | Residue |
| B | SER49 |
| B | TYR50 |
| B | GLN62 |
| B | HOH415 |
| B | HOH422 |
| B | HOH486 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01000","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"12468528","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1N4A","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01000","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"12468528","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12475936","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1N2Z","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N4A","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Site: {"description":"Important for BtuC binding","evidences":[{"source":"HAMAP-Rule","id":"MF_01000","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"12475936","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
